SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qh6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_0
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 3qh6 CT296
(Chlamydia
trachomatis) 		5 / 12 LEU A 113
ALA A 143
ILE A 102
SER A 116
ALA A  25
 None
 1.21A 2ejtA-3qh6A:
undetectable		 2ejtA-3qh6A:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXT_A_SAMA397_0
(PROBABLE
N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE
TRM1)		 3qh6 CT296
(Chlamydia
trachomatis) 		5 / 12 LEU A 113
ALA A 143
ILE A 102
SER A 116
ALA A  25
 None
 1.08A 3axtA-3qh6A:
undetectable		 3axtA-3qh6A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA277_0
(UNIVERSAL STRESS
PROTEIN)		 3qh6 CT296
(Chlamydia
trachomatis) 		3 / 3 ASP A  29
SER A  28
ARG A   0
 None
 1.02A 3loqA-3qh6A:
undetectable		 3loqA-3qh6A:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_2
(CYTOCHROME P450 3A5)		 3qh6 CT296
(Chlamydia
trachomatis) 		4 / 5 PHE A 125
PHE A 126
LEU A 124
LEU A  90
 None
 1.11A 5veuH-3qh6A:
undetectable		 5veuH-3qh6A:
17.95