SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qha'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBS_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE II)		 3qha PUTATIVE
OXIDOREDUCTASE
(Mycobacterium
avium) 		5 / 12 PHE A 157
LEU A  69
ILE A  72
ALA A  98
ALA A 125
 None
 1.06A 1cbsA-3qhaA:
undetectable		 1cbsA-3qhaA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3qha PUTATIVE
OXIDOREDUCTASE
(Mycobacterium
avium) 		4 / 7 SER A 128
ARG A 180
LEU A 178
THR A 184
 None
 1.15A 2f78A-3qhaA:
undetectable		 2f78A-3qhaA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FR3_A_REAA300_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
2)		 3qha PUTATIVE
OXIDOREDUCTASE
(Mycobacterium
avium) 		5 / 12 PHE A 157
LEU A  69
ILE A  72
ALA A  98
ALA A 125
 None
 1.04A 2fr3A-3qhaA:
undetectable		 2fr3A-3qhaA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_A_SAMA301_0
(YCGJ)		 3qha PUTATIVE
OXIDOREDUCTASE
(Mycobacterium
avium) 		5 / 12 GLY A 173
GLY A 171
ASP A 124
ALA A 125
HIS A 166
 None
 0.91A 2gluA-3qhaA:
6.7		 2gluA-3qhaA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_B_SAMB302_0
(YCGJ)		 3qha PUTATIVE
OXIDOREDUCTASE
(Mycobacterium
avium) 		5 / 12 GLY A 173
GLY A 171
ALA A 125
ALA A 167
HIS A 166
 None
 0.81A 2gluB-3qhaA:
5.0		 2gluB-3qhaA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC47_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 3qha PUTATIVE
OXIDOREDUCTASE
(Mycobacterium
avium) 		4 / 4 GLY A 171
GLY A 144
GLY A 168
GLY A 173
 None
 0.54A 3bogC-3qhaA:
undetectable		 3bogC-3qhaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DVAD47_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 3qha PUTATIVE
OXIDOREDUCTASE
(Mycobacterium
avium) 		4 / 4 GLY A 171
GLY A 144
GLY A 168
GLY A 173
 None
 0.53A 3bogD-3qhaA:
undetectable		 3bogD-3qhaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PRS_A_RITA1001_1
(ENDOTHIAPEPSIN)		 3qha PUTATIVE
OXIDOREDUCTASE
(Mycobacterium
avium) 		5 / 10 ALA A  88
ILE A 103
LEU A 111
THR A 174
ILE A 153
 None
 1.24A 3prsA-3qhaA:
undetectable		 3prsA-3qhaA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AT0_A_ACTA1490_0
(3-KETOSTEROID-DELTA4
-5ALPHA-DEHYDROGENAS
E)		 3qha PUTATIVE
OXIDOREDUCTASE
(Mycobacterium
avium) 		3 / 3 GLU A 252
TYR A 276
SER A 256
 None
 1.01A 4at0A-3qhaA:
1.9		 4at0A-3qhaA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F84_A_SAMA501_0
(GERANYL DIPHOSPHATE
2-C-METHYLTRANSFERAS
E)		 3qha PUTATIVE
OXIDOREDUCTASE
(Mycobacterium
avium) 		5 / 12 GLY A  18
GLY A  23
VAL A  74
THR A  73
VAL A  61
 None
 1.02A 4f84A-3qhaA:
5.1		 4f84A-3qhaA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F84_A_SAMA501_0
(GERANYL DIPHOSPHATE
2-C-METHYLTRANSFERAS
E)		 3qha PUTATIVE
OXIDOREDUCTASE
(Mycobacterium
avium) 		5 / 12 GLY A  18
GLY A  23
VAL A  74
THR A  73
VAL A  64
 None
 0.92A 4f84A-3qhaA:
5.1		 4f84A-3qhaA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KT0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 3qha PUTATIVE
OXIDOREDUCTASE
(Mycobacterium
avium) 		5 / 11 GLY A  54
ALA A  27
GLY A  36
ILE A 122
LEU A 115
 None
 1.03A 4kt0A-3qhaA:
undetectable
4kt0J-3qhaA:
undetectable		 4kt0A-3qhaA:
18.41
4kt0J-3qhaA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_C_FUAC1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3qha PUTATIVE
OXIDOREDUCTASE
(Mycobacterium
avium) 		3 / 3 VAL A 143
HIS A 121
VAL A  96
 None
 0.69A 5jmnC-3qhaA:
undetectable		 5jmnC-3qhaA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OTR_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3qha PUTATIVE
OXIDOREDUCTASE
(Mycobacterium
avium) 		4 / 5 TYR A 150
VAL A 143
PRO A 170
ALA A 167
 None
 1.12A 5otrA-3qhaA:
undetectable		 5otrA-3qhaA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_B_ACTB804_0
(UNCHARACTERIZED
PROTEIN)		 3qha PUTATIVE
OXIDOREDUCTASE
(Mycobacterium
avium) 		4 / 4 HIS A  71
VAL A  96
LEU A  69
ALA A  98
 None
 1.20A 6d8pB-3qhaA:
2.2		 6d8pB-3qhaA:
18.62