SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qhb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_A_DAHA208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 3qhb SYMERYTHRIN
(Cyanophora
paradoxa) 		5 / 11 GLU A  71
HIS A  74
GLU A 128
ILE A 158
GLU A 162
 FE  A 182 ( 2.5A)
None
FE  A 182 (-1.9A)
None
FE  A 182 ( 2.6A)
 0.92A 1rnrA-3qhbA:
9.6		 1rnrA-3qhbA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_A_DAHA208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 3qhb SYMERYTHRIN
(Cyanophora
paradoxa) 		5 / 11 GLU A 162
HIS A 165
GLU A  37
ILE A  67
GLU A  71
 FE  A 182 ( 2.6A)
FE  A 182 (-3.3A)
FE  A 181 (-2.4A)
None
FE  A 182 ( 2.5A)
 0.81A 1rnrA-3qhbA:
9.6		 1rnrA-3qhbA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_B_DAHB208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 3qhb SYMERYTHRIN
(Cyanophora
paradoxa) 		5 / 12 GLU A  71
HIS A  74
GLU A 128
ILE A 158
GLU A 162
 FE  A 182 ( 2.5A)
None
FE  A 182 (-1.9A)
None
FE  A 182 ( 2.6A)
 0.90A 1rnrB-3qhbA:
9.6		 1rnrB-3qhbA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_B_DAHB208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 3qhb SYMERYTHRIN
(Cyanophora
paradoxa) 		5 / 12 GLU A 162
HIS A 165
GLU A  37
ILE A  67
GLU A  71
 FE  A 182 ( 2.6A)
FE  A 182 (-3.3A)
FE  A 181 (-2.4A)
None
FE  A 182 ( 2.5A)
 0.82A 1rnrB-3qhbA:
9.6		 1rnrB-3qhbA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_A_SAMA302_0
(HYPOTHETICAL PROTEIN
PH0226)		 3qhb SYMERYTHRIN
(Cyanophora
paradoxa) 		5 / 12 ALA A 120
GLY A 116
ALA A 124
ILE A 103
PHE A  64
 None
 1.14A 1ve3A-3qhbA:
undetectable		 1ve3A-3qhbA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_B_SAMB301_0
(HYPOTHETICAL PROTEIN
PH0226)		 3qhb SYMERYTHRIN
(Cyanophora
paradoxa) 		5 / 12 ALA A 120
GLY A 116
ALA A 124
ILE A 103
PHE A  64
 None
 1.13A 1ve3B-3qhbA:
undetectable		 1ve3B-3qhbA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ROX_B_T44B128_1
(TRANSTHYRETIN)		 3qhb SYMERYTHRIN
(Cyanophora
paradoxa) 		4 / 6 GLU A  37
ALA A  30
LEU A  81
THR A  26
 FE  A 181 (-2.4A)
None
None
None
 0.99A 2roxB-3qhbA:
undetectable		 2roxB-3qhbA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM7_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3qhb SYMERYTHRIN
(Cyanophora
paradoxa) 		4 / 7 ALA A  75
TYR A 136
ILE A 158
HIS A 165
 None
None
None
FE  A 182 (-3.3A)
 0.98A 2zm7A-3qhbA:
undetectable		 2zm7A-3qhbA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_2
(CYTOCHROME P450 3A4)		 3qhb SYMERYTHRIN
(Cyanophora
paradoxa) 		5 / 9 ILE A 130
ARG A 119
LEU A 121
GLU A 122
GLY A  12
 None
 1.28A 3nxuB-3qhbA:
undetectable		 3nxuB-3qhbA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HQA_A_ACRA705_1
(ALPHA-GLUCOSIDASE)		 3qhb SYMERYTHRIN
(Cyanophora
paradoxa) 		5 / 12 GLU A 162
VAL A 127
GLU A 131
GLU A  37
GLU A  71
 FE  A 182 ( 2.6A)
None
FE  A 181 (-2.5A)
FE  A 181 (-2.4A)
FE  A 182 ( 2.5A)
 1.10A 5hqaA-3qhbA:
0.6		 5hqaA-3qhbA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PAH_A_LDPA600_1
(PHENYLALANINE
4-MONOOXYGENASE)		 3qhb SYMERYTHRIN
(Cyanophora
paradoxa) 		4 / 4 HIS A  74
HIS A 165
TYR A  45
GLU A  71
 None
FE  A 182 (-3.3A)
None
FE  A 182 ( 2.5A)
 1.37A 5pahA-3qhbA:
undetectable		 5pahA-3qhbA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3qhb SYMERYTHRIN
(Cyanophora
paradoxa) 		4 / 6 MET A  63
ALA A 120
LEU A 117
ALA A  52
 None
 1.05A 6fosB-3qhbA:
undetectable		 6fosB-3qhbA:
22.36