SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qhf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7W_A_MTXA301_1
(PTERIDINE REDUCTASE)		 3qhf HUMAN MONOCLONAL
ANTIBODY DEL2D1,
FAB HEAVY CHAIN
(Homo
sapiens) 		5 / 12 ARG H  66
PRO H  41
LEU H  20
LEU H  18
ASP H  86
 None
 1.36A 1e7wA-3qhfH:
undetectable		 1e7wA-3qhfH:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB927_0
(FERROCHELATASE)		 3qhf HUMAN MONOCLONAL
ANTIBODY DEL2D1,
FAB HEAVY CHAIN
(Homo
sapiens) 		3 / 3 LEU H 140
PRO H 126
ARG H 222
 None
 0.60A 2qd4B-3qhfH:
undetectable		 2qd4B-3qhfH:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LDO_A_ALEA1402_1
(LYSOZYME, BETA-2
ADRENERGIC RECEPTOR)		 3qhf HUMAN MONOCLONAL
ANTIBODY DEL2D1,
FAB HEAVY CHAIN
(Homo
sapiens) 		5 / 10 VAL H 171
VAL H 191
SER H 189
ASN H 209
ASN H 162
 None
 1.45A 4ldoA-3qhfH:
undetectable		 4ldoA-3qhfH:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 3qhf HUMAN MONOCLONAL
ANTIBODY DEL2D1,
FAB HEAVY CHAIN
(Homo
sapiens) 		5 / 11 SER H 197
GLY H 136
THR H 137
ALA H 138
THR H 133
 None
 0.99A 4qvyH-3qhfH:
undetectable		 4qvyH-3qhfH:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3qhf HUMAN MONOCLONAL
ANTIBODY DEL2D1,
FAB HEAVY CHAIN
(Homo
sapiens) 		5 / 12 SER H 197
GLY H 136
THR H 137
ALA H 138
THR H 133
 None
 0.99A 4qvyV-3qhfH:
undetectable
4qvyW-3qhfH:
undetectable		 4qvyV-3qhfH:
19.69
4qvyW-3qhfH:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3qhf HUMAN MONOCLONAL
ANTIBODY DEL2D1,
FAB HEAVY CHAIN
(Homo
sapiens) 		5 / 11 SER H 197
GLY H 136
THR H 137
ALA H 138
THR H 133
 None
 0.98A 5bxnH-3qhfH:
undetectable
5bxnI-3qhfH:
undetectable		 5bxnH-3qhfH:
20.95
5bxnI-3qhfH:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 3qhf HUMAN MONOCLONAL
ANTIBODY DEL2D1,
FAB HEAVY CHAIN
(Homo
sapiens) 		5 / 11 SER H 197
GLY H 136
THR H 137
ALA H 138
THR H 133
 None
 0.97A 5d0xV-3qhfH:
undetectable		 5d0xV-3qhfH:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3qhf HUMAN MONOCLONAL
ANTIBODY DEL2D1,
FAB HEAVY CHAIN
(Homo
sapiens) 		5 / 12 SER H 197
GLY H 136
THR H 137
ALA H 138
THR H 133
 None
 0.94A 5l5fH-3qhfH:
undetectable
5l5fI-3qhfH:
undetectable		 5l5fH-3qhfH:
19.69
5l5fI-3qhfH:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3qhf HUMAN MONOCLONAL
ANTIBODY DEL2D1,
FAB HEAVY CHAIN
(Homo
sapiens) 		5 / 12 SER H 197
GLY H 136
THR H 137
ALA H 138
THR H 133
 None
 0.94A 5l5fV-3qhfH:
undetectable
5l5fW-3qhfH:
undetectable		 5l5fV-3qhfH:
19.69
5l5fW-3qhfH:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRZ_A_H8JA1206_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 3qhf HUMAN MONOCLONAL
ANTIBODY DEL2D1,
FAB HEAVY CHAIN
(Homo
sapiens) 		5 / 12 VAL H 219
THR H 217
VAL H 223
GLY H 118
VAL H 154
 None
 1.07A 6drzA-3qhfH:
undetectable		 6drzA-3qhfH:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_B_68HB405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3qhf HUMAN MONOCLONAL
ANTIBODY DEL2D1,
FAB HEAVY CHAIN
(Homo
sapiens) 		5 / 12 VAL H 171
VAL H 191
SER H 189
ASN H 209
ASN H 162
 None
 1.41A 6h7mB-3qhfH:
undetectable		 6h7mB-3qhfH:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_H_BO2H301_0
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3qhf HUMAN MONOCLONAL
ANTIBODY DEL2D1,
FAB HEAVY CHAIN
(Homo
sapiens) 		5 / 12 SER H 197
GLY H 136
THR H 137
ALA H 138
THR H 133
 None
 1.07A 6hwdH-3qhfH:
undetectable
6hwdI-3qhfH:
undetectable		 6hwdH-3qhfH:
15.42
6hwdI-3qhfH:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_V_BO2V301_0
(PROTEASOME SUBUNIT
BETA TYPE-2)		 3qhf HUMAN MONOCLONAL
ANTIBODY DEL2D1,
FAB HEAVY CHAIN
(Homo
sapiens) 		5 / 11 SER H 197
GLY H 136
THR H 137
ALA H 138
THR H 133
 None
 1.07A 6hwdV-3qhfH:
undetectable		 6hwdV-3qhfH:
15.42