SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qhq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA801_1
(TRANSPORTER)		 3qhq SAG0897 FAMILY
CRISPR-ASSOCIATED
PROTEIN
(Streptococcus
agalactiae) 		5 / 11 LEU A  21
LEU A 196
ILE A   4
PHE A  36
LEU A  47
 None
 1.18A 2q6hA-3qhqA:
undetectable		 2q6hA-3qhqA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QJU_A_DSMA801_1
(TRANSPORTER)		 3qhq SAG0897 FAMILY
CRISPR-ASSOCIATED
PROTEIN
(Streptococcus
agalactiae) 		5 / 11 LEU A  21
LEU A 196
ILE A   4
PHE A  36
LEU A  47
 None
 1.17A 2qjuA-3qhqA:
2.6		 2qjuA-3qhqA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_B_TOPB200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 3qhq SAG0897 FAMILY
CRISPR-ASSOCIATED
PROTEIN
(Streptococcus
agalactiae) 		5 / 12 LEU A  32
LEU A 196
VAL A 166
ILE A   4
LEU A  15
 None
 1.04A 3fl9B-3qhqA:
undetectable		 3fl9B-3qhqA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_G_TOPG200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 3qhq SAG0897 FAMILY
CRISPR-ASSOCIATED
PROTEIN
(Streptococcus
agalactiae) 		5 / 12 LEU A  32
LEU A 196
VAL A 166
ILE A   4
LEU A  15
 None
 0.94A 3fl9G-3qhqA:
undetectable		 3fl9G-3qhqA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7A_B_RGZB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3qhq SAG0897 FAMILY
CRISPR-ASSOCIATED
PROTEIN
(Streptococcus
agalactiae) 		5 / 12 LEU A  45
LEU A  47
LEU A 164
ILE A   4
TYR A 156
 None
 0.90A 4a7aB-3qhqA:
undetectable		 4a7aB-3qhqA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 3qhq SAG0897 FAMILY
CRISPR-ASSOCIATED
PROTEIN
(Streptococcus
agalactiae) 		5 / 12 LEU A   9
LEU A 194
ILE A  23
LEU A  32
PHE A   6
 None
 0.96A 4odrA-3qhqA:
undetectable
4odrB-3qhqA:
undetectable		 4odrA-3qhqA:
19.92
4odrB-3qhqA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3qhq SAG0897 FAMILY
CRISPR-ASSOCIATED
PROTEIN
(Streptococcus
agalactiae) 		4 / 4 LEU A 194
TYR A 202
PRO A 198
ILE A  23
 None
 1.12A 5esgA-3qhqA:
undetectable		 5esgA-3qhqA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_A_TLFA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3qhq SAG0897 FAMILY
CRISPR-ASSOCIATED
PROTEIN
(Streptococcus
agalactiae) 		3 / 3 LEU A 159
TYR A  69
SER A  73
 None
 0.86A 5iktA-3qhqA:
undetectable		 5iktA-3qhqA:
19.10