SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qi7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KLM_A_SPPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 3qi7 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Clostridioides
difficile) 		5 / 11 LEU A 341
VAL A 116
PRO A 144
LEU A 160
PRO A 335
 None
 1.13A 1klmA-3qi7A:
undetectable		 1klmA-3qi7A:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 3qi7 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Clostridioides
difficile) 		4 / 7 MET A  55
ILE A 339
PHE A 369
GLU A  58
 None
 1.48A 2nsiA-3qi7A:
undetectable
2nsiB-3qi7A:
undetectable		 2nsiA-3qi7A:
20.54
2nsiB-3qi7A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFB_A_ACTA501_0
(METHYL-ACCEPTING
CHEMOTAXIS
TRANSDUCER)		 3qi7 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Clostridioides
difficile) 		4 / 7 MET A 330
VAL A 162
ARG A 167
ILE A 389
 None
 1.09A 2yfbA-3qi7A:
undetectable		 2yfbA-3qi7A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3qi7 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Clostridioides
difficile) 		4 / 8 ILE A 204
ASN A 219
VAL A 256
GLY A 255
 None
 0.94A 3em0B-3qi7A:
undetectable		 3em0B-3qi7A:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_B_017B200_2
(FIV PROTEASE)		 3qi7 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Clostridioides
difficile) 		5 / 9 GLY A 179
ALA A 180
ASP A 250
ILE A 251
ILE A 394
 None
 1.01A 3ogpB-3qi7A:
undetectable		 3ogpB-3qi7A:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_0
(WBDD)		 3qi7 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Clostridioides
difficile) 		5 / 12 ILE A 100
ILE A 103
SER A 118
VAL A 117
ILE A 115
 None
 0.87A 4ax8A-3qi7A:
2.5		 4ax8A-3qi7A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZV_A_SAMA1474_0
(WBDD)		 3qi7 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Clostridioides
difficile) 		5 / 12 ILE A 100
ILE A 103
SER A 118
VAL A 117
ILE A 115
 None
 0.86A 4azvA-3qi7A:
3.0		 4azvA-3qi7A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQB_B_017B101_2
(ASPARTYL PROTEASE)		 3qi7 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Clostridioides
difficile) 		5 / 10 LEU A 152
ASP A 147
GLY A 123
ILE A 103
VAL A 156
 None
 0.92A 4dqbB-3qi7A:
undetectable		 4dqbB-3qi7A:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQH_B_017B101_2
(WILD-TYPE HIV-1
PROTEASE DIMER)		 3qi7 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Clostridioides
difficile) 		5 / 10 LEU A 152
ASP A 147
GLY A 123
ILE A 103
VAL A 156
 None
 0.94A 4dqhB-3qi7A:
undetectable		 4dqhB-3qi7A:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_E_SPME202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3qi7 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Clostridioides
difficile) 		4 / 5 GLU A  65
GLU A  66
TYR A  63
GLU A  64
 None
 1.47A 4r87E-3qi7A:
undetectable		 4r87E-3qi7A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 3qi7 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Clostridioides
difficile) 		3 / 3 LYS A  38
ASP A  36
ILE A 339
 None
 0.91A 5kc4E-3qi7A:
undetectable		 5kc4E-3qi7A:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3qi7 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Clostridioides
difficile) 		5 / 10 ILE A 389
MET A  55
ILE A 141
ALA A 143
LEU A 334
 None
 1.45A 5zjiB-3qi7A:
undetectable		 5zjiB-3qi7A:
11.38