SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qil'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MXG_A_ACRA443_1 (ALPHA AMYLASE)	3qil	CLATHRIN HEAVY CHAIN 1 (Bos taurus)	4 / 8	SER A1502 LEU A1549 ASP A1546 GLU A1552	None	1.13A	1mxgA-3qilA: undetectable	1mxgA-3qilA: 13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BR4_A_SAMA301_1 (CEPHALOSPORIN HYDROXYLASE CMCI)	3qil	CLATHRIN HEAVY CHAIN 1 (Bos taurus)	3 / 3	LYS A1522 ASP A1546 ASP A1575	None	0.93A	2br4A-3qilA: undetectable	2br4A-3qilA: 20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WNU_B_QDNB602_1 (CYTOCHROME P450 2D6)	3qil	CLATHRIN HEAVY CHAIN 1 (Bos taurus)	5 / 9	LEU A1585 GLU A1551 GLN A1555 PHE A1557 ALA A1568	None	1.22A	4wnuB-3qilA: undetectable	4wnuB-3qilA: 14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5GWZ_D_010D6_0 (N-[(5-METHYLISOXAZOL -3-YL)CARBONYL]ALANY L-L-VALYL-N~1~-((1R, 2Z)-4-(BENZYLOXY)-4- OXO-1-{[(3R)-2-OXOPY RROLIDIN-3-YL]METHYL }BUT-2-ENYL)-L-LEUCI NAMIDE PEDV MAIN PROTEASE)	3qil	CLATHRIN HEAVY CHAIN 1 (Bos taurus)	3 / 3	MET A1520 HIS A1505 GLY A1517	None	0.84A	5gwzB-3qilA: undetectable	5gwzB-3qilA: 18.94

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1MXG_A_ACRA443_1","ALPHA AMYLASE","3qil","CLATHRIN HEAVY CHAIN 1","Bos taurus",4,"SER A1502;LEU A1549;ASP A1546;GLU A1552","None","1.13A","1mxgA-3qilA:undetectable","1mxgA-3qilA:13.71"],["2BR4_A_SAMA301_1","CEPHALOSPORIN HYDROXYLASE CMCI","3qil","CLATHRIN HEAVY CHAIN 1","Bos taurus",3,"LYS A1522;ASP A1546;ASP A1575","None","0.93A","2br4A-3qilA:undetectable","2br4A-3qilA:20.94"],["4WNU_B_QDNB602_1","CYTOCHROME P450 2D6","3qil","CLATHRIN HEAVY CHAIN 1","Bos taurus",5,"LEU A1585;GLU A1551;GLN A1555;PHE A1557;ALA A1568","None","1.22A","4wnuB-3qilA:undetectable","4wnuB-3qilA:14.29"],["5GWZ_D_010D6_0","N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE;PEDV MAIN PROTEASE","3qil","CLATHRIN HEAVY CHAIN 1","Bos taurus",3,"MET A1520;HIS A1505;GLY A1517","None","0.84A","5gwzB-3qilA:undetectable","5gwzB-3qilA:18.94"]]