SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qiu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FQS_A_LYAA302_1
(THYMIDYLATE SYNTHASE)		 3qiu TCR 226 ALPHA CHAIN
(Mus
musculus) 		5 / 12 HIS C  72
LEU C  48
GLY C  51
VAL C  31
ALA C  30
 None
 1.21A 4fqsA-3qiuC:
undetectable		 4fqsA-3qiuC:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FQS_B_LYAB302_1
(THYMIDYLATE SYNTHASE)		 3qiu TCR 226 ALPHA CHAIN
(Mus
musculus) 		5 / 12 HIS C  72
LEU C  48
GLY C  51
VAL C  31
ALA C  30
 None
 1.19A 4fqsB-3qiuC:
undetectable		 4fqsB-3qiuC:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		 3qiu TCR 226 ALPHA CHAIN
(Mus
musculus) 		3 / 3 THR C  70
SER C  69
TYR C  68
 None
 0.85A 5jsdA-3qiuC:
undetectable		 5jsdA-3qiuC:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		 3qiu TCR 226 ALPHA CHAIN
(Mus
musculus) 		3 / 3 THR C  70
SER C  69
TYR C  68
 None
 0.86A 5jsdB-3qiuC:
undetectable		 5jsdB-3qiuC:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		 3qiu TCR 226 ALPHA CHAIN
(Mus
musculus) 		3 / 3 THR C  70
SER C  69
TYR C  68
 None
 0.85A 5jsdC-3qiuC:
undetectable		 5jsdC-3qiuC:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		 3qiu TCR 226 ALPHA CHAIN
(Mus
musculus) 		3 / 3 THR C  70
SER C  69
TYR C  68
 None
 0.85A 5jseA-3qiuC:
undetectable		 5jseA-3qiuC:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		 3qiu TCR 226 ALPHA CHAIN
(Mus
musculus) 		3 / 3 THR C  70
SER C  69
TYR C  68
 None
 0.84A 5jseB-3qiuC:
undetectable		 5jseB-3qiuC:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		 3qiu TCR 226 ALPHA CHAIN
(Mus
musculus) 		3 / 3 THR C  70
SER C  69
TYR C  68
 None
 0.84A 5jseC-3qiuC:
undetectable		 5jseC-3qiuC:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
7DFR_A_FOLA161_1
(DIHYDROFOLATE
REDUCTASE)		 3qiu TCR 226 ALPHA CHAIN
(Mus
musculus) 		3 / 3 ASP C 159
LEU C  78
ARG C  57
 None
 0.71A 7dfrA-3qiuC:
undetectable		 7dfrA-3qiuC:
22.22