SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qiv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UAY_B_ADNB1002_1
(TYPE II
3-HYDROXYACYL-COA
DEHYDROGENASE)		 3qiv SHORT-CHAIN
DEHYDROGENASE OR
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Mycobacterium
avium) 		6 / 10 GLY A  12
ASP A  36
ASP A  62
VAL A  63
ALA A  90
VAL A 115
 None
 0.56A 1uayB-3qivA:
22.8		 1uayB-3qivA:
27.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_A_GBNA502_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 3qiv SHORT-CHAIN
DEHYDROGENASE OR
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Mycobacterium
avium) 		4 / 8 GLY A  54
THR A  55
ALA A  56
VAL A  10
 None
 0.75A 2a1hA-3qivA:
undetectable
2a1hB-3qivA:
undetectable		 2a1hA-3qivA:
22.51
2a1hB-3qivA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_B_GBNB501_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 3qiv SHORT-CHAIN
DEHYDROGENASE OR
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Mycobacterium
avium) 		4 / 8 VAL A  10
GLY A  54
THR A  55
ALA A  56
 None
 0.74A 2a1hA-3qivA:
undetectable
2a1hB-3qivA:
undetectable		 2a1hA-3qivA:
22.51
2a1hB-3qivA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNJ_A_225A501_1
(CYTOCHROME P450 2C8)		 3qiv SHORT-CHAIN
DEHYDROGENASE OR
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Mycobacterium
avium) 		5 / 10 ILE A  83
ALA A  73
VAL A  59
VAL A  33
VAL A  61
 None
 1.06A 2nnjA-3qivA:
undetectable		 2nnjA-3qivA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 3qiv SHORT-CHAIN
DEHYDROGENASE OR
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Mycobacterium
avium) 		5 / 12 GLY A  14
ILE A  37
ASN A  38
ASP A  62
VAL A  63
 None
 0.89A 2zzmA-3qivA:
7.3		 2zzmA-3qivA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 3qiv SHORT-CHAIN
DEHYDROGENASE OR
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Mycobacterium
avium) 		5 / 12 GLY A  14
ILE A  37
ASN A  38
ASP A  62
VAL A  63
 None
 0.92A 2zznA-3qivA:
7.1		 2zznA-3qivA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_A_ADNA401_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 3qiv SHORT-CHAIN
DEHYDROGENASE OR
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Mycobacterium
avium) 		5 / 10 ASP A  36
ILE A  37
ALA A  41
ASP A  62
VAL A  61
 None
 1.24A 3ay0A-3qivA:
7.3		 3ay0A-3qivA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_A_ADNA401_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 3qiv SHORT-CHAIN
DEHYDROGENASE OR
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Mycobacterium
avium) 		5 / 10 ASP A  36
ILE A  37
ASN A  38
ALA A  41
ASP A  62
 None
 0.92A 3ay0A-3qivA:
7.3		 3ay0A-3qivA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_A_ADNA401_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 3qiv SHORT-CHAIN
DEHYDROGENASE OR
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Mycobacterium
avium) 		5 / 10 ASP A  36
ILE A  37
ASN A  38
ASP A  62
VAL A  63
 None
 0.76A 3ay0A-3qivA:
7.3		 3ay0A-3qivA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_B_ADNB402_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 3qiv SHORT-CHAIN
DEHYDROGENASE OR
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Mycobacterium
avium) 		6 / 10 GLY A  14
ASP A  36
ILE A  37
ASN A  38
ASP A  62
VAL A  63
 None
 0.87A 3ay0B-3qivA:
7.1		 3ay0B-3qivA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMF_A_SAMA388_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 3qiv SHORT-CHAIN
DEHYDROGENASE OR
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Mycobacterium
avium) 		5 / 12 GLY A  12
GLY A  14
ASP A  62
VAL A  63
VAL A 115
 None
 0.94A 3dmfA-3qivA:
7.5		 3dmfA-3qivA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q87_B_SAMB300_0
(N6 ADENINE SPECIFIC
DNA METHYLASE)		 3qiv SHORT-CHAIN
DEHYDROGENASE OR
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Mycobacterium
avium) 		5 / 12 GLY A  12
ILE A  17
ASP A  36
ASN A  38
ASP A  62
 None
 1.07A 3q87B-3qivA:
7.2		 3q87B-3qivA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV8_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3qiv SHORT-CHAIN
DEHYDROGENASE OR
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Mycobacterium
avium) 		6 / 12 GLY A  12
GLY A  14
ASP A  36
ILE A  37
ASP A  62
ALA A  90
 None
 1.16A 4iv8A-3qivA:
6.5		 4iv8A-3qivA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV8_B_SAMB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3qiv SHORT-CHAIN
DEHYDROGENASE OR
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Mycobacterium
avium) 		6 / 12 GLY A  12
GLY A  14
ASP A  36
ILE A  37
ASP A  62
ALA A  90
 None
 1.11A 4iv8B-3qivA:
6.6		 4iv8B-3qivA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3qiv SHORT-CHAIN
DEHYDROGENASE OR
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Mycobacterium
avium) 		4 / 5 ILE A  57
ASP A  74
GLU A  79
VAL A   7
 None
 1.15A 4nkxC-3qivA:
undetectable		 4nkxC-3qivA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_D_STRD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3qiv SHORT-CHAIN
DEHYDROGENASE OR
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Mycobacterium
avium) 		4 / 5 ILE A  57
ASP A  74
GLU A  79
VAL A   7
 None
 1.17A 4nkxD-3qivA:
undetectable		 4nkxD-3qivA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_B_032B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3qiv SHORT-CHAIN
DEHYDROGENASE OR
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Mycobacterium
avium) 		4 / 5 ILE A  92
PHE A 100
SER A 114
ASP A 105
 None
 1.43A 4rzvB-3qivA:
undetectable		 4rzvB-3qivA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVP_B_GBMB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 3qiv SHORT-CHAIN
DEHYDROGENASE OR
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Mycobacterium
avium) 		5 / 12 TYR A 128
LEU A 172
ASN A 141
LEU A 121
LEU A 164
 None
 1.36A 4yvpB-3qivA:
undetectable		 4yvpB-3qivA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		 3qiv SHORT-CHAIN
DEHYDROGENASE OR
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Mycobacterium
avium) 		4 / 7 ILE A 238
ILE A 179
SER A 143
LEU A 168
 None
 0.82A 5fukA-3qivA:
undetectable
5fukB-3qivA:
undetectable		 5fukA-3qivA:
23.51
5fukB-3qivA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HJI_A_ADNA401_1
(TRNA
(GUANINE(37)-N1)-MET
HYLTRANSFERASE TRM5A)		 3qiv SHORT-CHAIN
DEHYDROGENASE OR
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Mycobacterium
avium) 		5 / 11 GLY A  14
ILE A  37
ASN A  38
ASP A  62
VAL A  63
 None
 0.90A 5hjiA-3qivA:
7.4		 5hjiA-3qivA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LW1_B_ADNB401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 8)		 3qiv SHORT-CHAIN
DEHYDROGENASE OR
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Mycobacterium
avium) 		6 / 9 GLY A 119
VAL A  63
ALA A  69
ILE A   9
MET A  72
LEU A  86
 None
 1.43A 5lw1B-3qivA:
undetectable		 5lw1B-3qivA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LW1_E_ADNE401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 8)		 3qiv SHORT-CHAIN
DEHYDROGENASE OR
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Mycobacterium
avium) 		6 / 10 GLY A 119
VAL A  63
ALA A  69
ILE A   9
MET A  72
LEU A  86
 None
 1.39A 5lw1E-3qivA:
undetectable		 5lw1E-3qivA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WY0_A_SAMA800_0
(SMALL RNA
2'-O-METHYLTRANSFERA
SE)		 3qiv SHORT-CHAIN
DEHYDROGENASE OR
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Mycobacterium
avium) 		6 / 12 GLY A  12
GLY A  14
ASP A  36
ILE A  37
ASN A  38
ILE A  17
 None
 0.70A 5wy0A-3qivA:
5.8		 5wy0A-3qivA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WY0_A_SAMA800_0
(SMALL RNA
2'-O-METHYLTRANSFERA
SE)		 3qiv SHORT-CHAIN
DEHYDROGENASE OR
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Mycobacterium
avium) 		6 / 12 GLY A  12
GLY A  14
ASP A  36
ILE A  37
ASN A  38
VAL A  63
 None
 0.81A 5wy0A-3qivA:
5.8		 5wy0A-3qivA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_G_CHDG401_0
(BILE SALT HYDROLASE)		 3qiv SHORT-CHAIN
DEHYDROGENASE OR
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Mycobacterium
avium) 		5 / 10 ILE A 182
LEU A 219
ALA A  24
LEU A  25
GLU A 230
 None
 1.22A 5y7pG-3qivA:
undetectable		 5y7pG-3qivA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 3qiv SHORT-CHAIN
DEHYDROGENASE OR
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Mycobacterium
avium) 		4 / 8 VAL A 159
ASN A 162
ASN A 240
ILE A 238
 None
 1.08A 6hzpA-3qivA:
undetectable		 6hzpA-3qivA:
19.67