SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qj3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		 3qj3 CATHEPSIN L-LIKE
PROTEIN
(Tenebrio
molitor) 		4 / 6 ASN A 287
PHE A 299
GLY A 248
TYR A 250
 None
 1.11A 1c8lA-3qj3A:
undetectable		 1c8lA-3qj3A:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		 3qj3 CATHEPSIN L-LIKE
PROTEIN
(Tenebrio
molitor) 		4 / 6 ASN A 287
PHE A 299
GLY A 248
TYR A 250
 None
 1.12A 1gfzA-3qj3A:
undetectable		 1gfzA-3qj3A:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_2
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN)
IGG2B-KAPPA 40-50
FAB (LIGHT CHAIN))		 3qj3 CATHEPSIN L-LIKE
PROTEIN
(Tenebrio
molitor) 		4 / 7 SER A 288
SER A 249
TYR A  56
LEU A  58
 None
 1.05A 1ibgL-3qj3A:
undetectable		 1ibgL-3qj3A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3qj3 CATHEPSIN L-LIKE
PROTEIN
(Tenebrio
molitor) 		4 / 6 ASN A 287
PHE A 299
GLY A 248
TYR A 250
 None
 1.15A 1l5qA-3qj3A:
undetectable		 1l5qA-3qj3A:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3qj3 CATHEPSIN L-LIKE
PROTEIN
(Tenebrio
molitor) 		4 / 6 ASN A 287
PHE A 299
GLY A 248
TYR A 250
 None
 1.15A 1l5qB-3qj3A:
undetectable		 1l5qB-3qj3A:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_1
(MODIFICATION
METHYLASE RSRI)		 3qj3 CATHEPSIN L-LIKE
PROTEIN
(Tenebrio
molitor) 		3 / 3 ASP A 245
HIS A  76
ASP A 242
 None
 0.89A 1nw5A-3qj3A:
undetectable		 1nw5A-3qj3A:
22.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1STF_E_CCSE25_0
(PAPAIN
STEFIN B (CYSTATIN
B))		 3qj3 CATHEPSIN L-LIKE
PROTEIN
(Tenebrio
molitor) 		9 / 10 GLN A 123
GLY A 127
SER A 128
TRP A 130
PHE A 132
SER A 133
HIS A 267
ALA A 268
GLY A  77
 None
 0.40A 1stfE-3qj3A:
28.3
1stfI-3qj3A:
undetectable		 1stfE-3qj3A:
31.62
1stfI-3qj3A:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		 3qj3 CATHEPSIN L-LIKE
PROTEIN
(Tenebrio
molitor) 		4 / 6 THR A  41
GLU A  40
PHE A  35
ILE A  34
 None
 0.94A 2w98B-3qj3A:
undetectable		 2w98B-3qj3A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6R_C_CTCC1385_0
(TETX2 PROTEIN)		 3qj3 CATHEPSIN L-LIKE
PROTEIN
(Tenebrio
molitor) 		5 / 12 MET A  80
HIS A  76
GLY A  77
SER A 129
GLY A 310
 None
 1.22A 2y6rC-3qj3A:
undetectable		 2y6rC-3qj3A:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI8_A_HNQA255_1
(CATHEPSIN B)		 3qj3 CATHEPSIN L-LIKE
PROTEIN
(Tenebrio
molitor) 		4 / 7 GLN A 123
GLY A 127
HIS A 267
TRP A 289
 None
 0.47A 3ai8A-3qj3A:
25.2		 3ai8A-3qj3A:
28.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		 3qj3 CATHEPSIN L-LIKE
PROTEIN
(Tenebrio
molitor) 		4 / 5 ASN A 287
PHE A 299
GLY A 248
TYR A 250
 None
 1.11A 3bcrA-3qj3A:
undetectable		 3bcrA-3qj3A:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3qj3 CATHEPSIN L-LIKE
PROTEIN
(Tenebrio
molitor) 		4 / 6 ASN A 287
PHE A 299
GLY A 248
TYR A 250
 None
 1.10A 3dd1A-3qj3A:
undetectable		 3dd1A-3qj3A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3qj3 CATHEPSIN L-LIKE
PROTEIN
(Tenebrio
molitor) 		4 / 6 ASN A 287
PHE A 299
GLY A 248
TYR A 250
 None
 1.13A 3dd1B-3qj3A:
undetectable		 3dd1B-3qj3A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3qj3 CATHEPSIN L-LIKE
PROTEIN
(Tenebrio
molitor) 		4 / 6 ASN A 287
PHE A 299
GLY A 248
TYR A 250
 None
 1.12A 3ddsA-3qj3A:
undetectable		 3ddsA-3qj3A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3qj3 CATHEPSIN L-LIKE
PROTEIN
(Tenebrio
molitor) 		4 / 6 ASN A 287
PHE A 299
GLY A 248
TYR A 250
 None
 1.14A 3ddsB-3qj3A:
undetectable		 3ddsB-3qj3A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3qj3 CATHEPSIN L-LIKE
PROTEIN
(Tenebrio
molitor) 		4 / 6 ASN A 287
PHE A 299
GLY A 248
TYR A 250
 None
 1.10A 3ddwA-3qj3A:
undetectable		 3ddwA-3qj3A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3qj3 CATHEPSIN L-LIKE
PROTEIN
(Tenebrio
molitor) 		4 / 6 ASN A 287
PHE A 299
GLY A 248
TYR A 250
 None
 1.14A 3ddwB-3qj3A:
undetectable		 3ddwB-3qj3A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_D_ESTD600_1
(ESTROGEN RECEPTOR
BETA)		 3qj3 CATHEPSIN L-LIKE
PROTEIN
(Tenebrio
molitor) 		5 / 12 ALA A 232
LEU A 227
ILE A  91
LEU A 219
LEU A  99
 None
 1.15A 4j24D-3qj3A:
undetectable		 4j24D-3qj3A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_A_SAMA301_1
(UNCHARACTERIZED
PROTEIN MJ0489)		 3qj3 CATHEPSIN L-LIKE
PROTEIN
(Tenebrio
molitor) 		4 / 4 LYS A 121
ASP A 161
GLU A 190
THR A 135
 None
 1.38A 5d4uA-3qj3A:
0.0		 5d4uA-3qj3A:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_B_SAMB301_1
(UNCHARACTERIZED
PROTEIN MJ0489)		 3qj3 CATHEPSIN L-LIKE
PROTEIN
(Tenebrio
molitor) 		4 / 4 LYS A 121
ASP A 161
GLU A 190
THR A 135
 None
 1.39A 5d4uB-3qj3A:
undetectable		 5d4uB-3qj3A:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_C_SAMC301_1
(UNCHARACTERIZED
PROTEIN MJ0489)		 3qj3 CATHEPSIN L-LIKE
PROTEIN
(Tenebrio
molitor) 		4 / 4 LYS A 121
ASP A 161
GLU A 190
THR A 135
 None
 1.37A 5d4uC-3qj3A:
0.0		 5d4uC-3qj3A:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_D_SAMD301_1
(UNCHARACTERIZED
PROTEIN MJ0489)		 3qj3 CATHEPSIN L-LIKE
PROTEIN
(Tenebrio
molitor) 		4 / 4 LYS A 121
ASP A 161
GLU A 190
THR A 135
 None
 1.37A 5d4uD-3qj3A:
0.1		 5d4uD-3qj3A:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_A_486A801_2
(GLUCOCORTICOID
RECEPTOR)		 3qj3 CATHEPSIN L-LIKE
PROTEIN
(Tenebrio
molitor) 		3 / 3 TRP A 130
MET A 174
ASN A 175
 None
 1.32A 5uc1B-3qj3A:
undetectable		 5uc1B-3qj3A:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_1
(GLUCOCORTICOID
RECEPTOR)		 3qj3 CATHEPSIN L-LIKE
PROTEIN
(Tenebrio
molitor) 		3 / 3 TRP A 130
MET A 174
ASN A 175
 None
 1.33A 5uc1A-3qj3A:
undetectable		 5uc1A-3qj3A:
13.75