SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qjg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEY_B_EV1B1771_1
(CAMP AND
CAMP-INHIBITED CGMP
3', 5'-CYCLIC
PHOSPHODIESTERASE)		 3qjg EPIDERMIN
BIOSYNTHESIS PROTEIN
EPID
(Staphylococcus
aureus) 		4 / 8 LEU A 169
VAL A  32
ILE A  78
PHE A 113
 None
 0.98A 2weyB-3qjgA:
undetectable		 2weyB-3qjgA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 3qjg EPIDERMIN
BIOSYNTHESIS PROTEIN
EPID
(Staphylococcus
aureus) 		4 / 8 ILE A 112
ASN A 115
SER A  12
SER A  84
 None
FMN  A 501 (-4.2A)
FMN  A 501 (-2.6A)
None
 0.94A 2zw9B-3qjgA:
2.9		 2zw9B-3qjgA:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR4_X_PNTX101_0
(PROTEIN S100-B)		 3qjg EPIDERMIN
BIOSYNTHESIS PROTEIN
EPID
(Staphylococcus
aureus) 		3 / 3 CYH A 103
HIS A 104
PHE A 107
 None
 0.85A 3cr4X-3qjgA:
undetectable		 3cr4X-3qjgA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SP9_A_IL2A901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)		 3qjg EPIDERMIN
BIOSYNTHESIS PROTEIN
EPID
(Staphylococcus
aureus) 		5 / 12 CYH A 103
ILE A  94
LEU A 133
VAL A 138
ILE A  79
 None
 1.27A 3sp9A-3qjgA:
undetectable		 3sp9A-3qjgA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD2_1
(CYTOCHROME P450 2D6)		 3qjg EPIDERMIN
BIOSYNTHESIS PROTEIN
EPID
(Staphylococcus
aureus) 		5 / 9 LEU A  25
VAL A  32
LEU A  80
ILE A   7
PHE A 113
 None
 1.09A 3tbgD-3qjgA:
undetectable		 3tbgD-3qjgA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		 3qjg EPIDERMIN
BIOSYNTHESIS PROTEIN
EPID
(Staphylococcus
aureus) 		4 / 6 THR A  38
ASN A  39
GLY A  11
ILE A  79
 None
FMN  A 501 (-3.8A)
FMN  A 501 (-3.6A)
None
 0.84A 3w9tF-3qjgA:
undetectable		 3w9tF-3qjgA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QC6_B_KANB201_2
(BIFUNCTIONAL AAC/APH)		 3qjg EPIDERMIN
BIOSYNTHESIS PROTEIN
EPID
(Staphylococcus
aureus) 		3 / 3 LEU A 132
ASP A 135
TYR A 136
 None
 0.54A 4qc6B-3qjgA:
undetectable		 4qc6B-3qjgA:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		 3qjg EPIDERMIN
BIOSYNTHESIS PROTEIN
EPID
(Staphylococcus
aureus) 		3 / 3 TYR A  21
PRO A  81
LEU A   9
 None
 0.81A 6beoA-3qjgA:
undetectable		 6beoA-3qjgA:
3.70