SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qjh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KF6_B_ACTB704_0
(FUMARATE REDUCTASE
FLAVOPROTEIN
FUMARATE REDUCTASE
IRON-SULFUR PROTEIN)		 3qjh 5C.C7 BETA CHAIN
(Mus
musculus) 		3 / 3 ARG B  64
GLY B  85
ASP B  86
 None
 0.53A 1kf6A-3qjhB:
undetectable
1kf6B-3qjhB:
undetectable		 1kf6A-3qjhB:
16.94
1kf6B-3qjhB:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_0
(PCZA361.24)		 3qjh 5C.C7 BETA CHAIN
(Mus
musculus) 		5 / 12 GLY B  14
LEU B 112
SER B  87
GLY B  85
GLU B  83
 None
 1.05A 3g2oA-3qjhB:
undetectable		 3g2oA-3qjhB:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_B_SAMB600_0
(PCZA361.24)		 3qjh 5C.C7 BETA CHAIN
(Mus
musculus) 		5 / 12 GLY B  14
LEU B 112
SER B  87
GLY B  85
GLU B  83
 None
 1.03A 3g2oB-3qjhB:
undetectable		 3g2oB-3qjhB:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LCV_B_SAMB301_1
(SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM)		 3qjh 5C.C7 BETA CHAIN
(Mus
musculus) 		3 / 3 ARG B 208
ASP B 247
GLN B 142
 None
 0.91A 3lcvB-3qjhB:
undetectable		 3lcvB-3qjhB:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_C_LYAC304_2
(FOLATE RECEPTOR BETA)		 3qjh 5C.C7 BETA CHAIN
(Mus
musculus) 		3 / 3 TYR B 103
GLN B  56
TRP B  34
 None
 1.16A 4kn2C-3qjhB:
undetectable		 4kn2C-3qjhB:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF8_A_LBHA2004_1
(HDAC6 PROTEIN)		 3qjh 5C.C7 BETA CHAIN
(Mus
musculus) 		5 / 12 HIS B 157
PRO B 155
SER B  87
ASP B 188
TYR B 154
 None
 1.15A 5ef8A-3qjhB:
undetectable		 5ef8A-3qjhB:
20.42