SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qjp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DBB_H_STRH229_1
(IGG1-KAPPA DB3 FAB
(HEAVY CHAIN)
IGG1-KAPPA DB3 FAB
(LIGHT CHAIN))		 3qjp PUTATIVE
UNCHARACTERIZED
PROTEIN PH0350
(Pyrococcus
horikoshii) 		4 / 8 GLY A 229
GLY A 231
TYR A  25
VAL A   5
 None
 0.89A 1dbbH-3qjpA:
undetectable
1dbbL-3qjpA:
undetectable		 1dbbH-3qjpA:
17.39
1dbbL-3qjpA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHS_A_CLMA999_0
(PROTEIN
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE))		 3qjp PUTATIVE
UNCHARACTERIZED
PROTEIN PH0350
(Pyrococcus
horikoshii) 		5 / 12 VAL A   5
ILE A   3
ILE A  90
ILE A  28
VAL A 109
 None
 0.94A 1qhsA-3qjpA:
undetectable		 1qhsA-3qjpA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA999_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 3qjp PUTATIVE
UNCHARACTERIZED
PROTEIN PH0350
(Pyrococcus
horikoshii) 		5 / 12 VAL A   5
ILE A   3
ILE A  90
ILE A  28
VAL A 109
 None
 0.93A 1qhyA-3qjpA:
undetectable		 1qhyA-3qjpA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EFJ_A_37TA502_1
(3,7-DIMETHYLXANTHINE
METHYLTRANSFERASE)		 3qjp PUTATIVE
UNCHARACTERIZED
PROTEIN PH0350
(Pyrococcus
horikoshii) 		5 / 12 TYR A 220
LEU A 129
ILE A  79
ILE A  87
TYR A  78
 None
 1.48A 2efjA-3qjpA:
undetectable		 2efjA-3qjpA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3qjp PUTATIVE
UNCHARACTERIZED
PROTEIN PH0350
(Pyrococcus
horikoshii) 		4 / 6 GLY A 211
GLY A 121
PHE A 126
PHE A 224
 None
 1.01A 2qx6A-3qjpA:
undetectable
2qx6B-3qjpA:
undetectable		 2qx6A-3qjpA:
18.25
2qx6B-3qjpA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 3qjp PUTATIVE
UNCHARACTERIZED
PROTEIN PH0350
(Pyrococcus
horikoshii) 		3 / 3 ARG A 201
ASP A 153
ASP A 148
 A  R  10 ( 3.4A)
None
A  R  10 ( 4.0A)
 0.93A 3jb2A-3qjpA:
undetectable		 3jb2A-3qjpA:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3003_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3qjp PUTATIVE
UNCHARACTERIZED
PROTEIN PH0350
(Pyrococcus
horikoshii) 		4 / 6 ILE A 112
VAL A 109
LEU A   7
LEU A  77
 None
 0.72A 3kp6A-3qjpA:
undetectable
3kp6B-3qjpA:
undetectable		 3kp6A-3qjpA:
22.73
3kp6B-3qjpA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_C_BEZC264_0
(CARNITINYL-COA
DEHYDRATASE)		 3qjp PUTATIVE
UNCHARACTERIZED
PROTEIN PH0350
(Pyrococcus
horikoshii) 		4 / 6 ALA A  40
LEU A  29
GLU A  36
ALA A  93
 None
 0.87A 3r9sC-3qjpA:
undetectable		 3r9sC-3qjpA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_A_DXCA92_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3qjp PUTATIVE
UNCHARACTERIZED
PROTEIN PH0350
(Pyrococcus
horikoshii) 		4 / 4 LYS A 189
PHE A 188
PHE A 207
VAL A 235
 G  R   5 ( 3.1A)
None
None
None
 1.38A 3rv5A-3qjpA:
0.0
3rv5B-3qjpA:
undetectable		 3rv5A-3qjpA:
14.88
3rv5B-3qjpA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_C_ZPCC1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3qjp PUTATIVE
UNCHARACTERIZED
PROTEIN PH0350
(Pyrococcus
horikoshii) 		5 / 12 PHE A  52
ILE A 200
ILE A  56
TYR A  20
VAL A 195
 None
None
U  R   3 ( 4.5A)
None
None
 1.26A 4a97B-3qjpA:
undetectable
4a97C-3qjpA:
undetectable		 4a97B-3qjpA:
20.50
4a97C-3qjpA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_A_20JA602_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 3qjp PUTATIVE
UNCHARACTERIZED
PROTEIN PH0350
(Pyrococcus
horikoshii) 		4 / 7 ILE A  87
ARG A  88
ILE A  90
ALA A  89
 None
 0.81A 4lv9A-3qjpA:
undetectable		 4lv9A-3qjpA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_B_20JB602_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 3qjp PUTATIVE
UNCHARACTERIZED
PROTEIN PH0350
(Pyrococcus
horikoshii) 		4 / 7 ILE A  87
ARG A  88
ILE A  90
ALA A  89
 None
 0.82A 4lv9B-3qjpA:
undetectable		 4lv9B-3qjpA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)		 3qjp PUTATIVE
UNCHARACTERIZED
PROTEIN PH0350
(Pyrococcus
horikoshii) 		5 / 12 VAL A 109
PRO A  98
PHE A  52
ILE A  28
GLN A  27
 None
 1.36A 5hgcA-3qjpA:
undetectable		 5hgcA-3qjpA:
21.04