SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qk9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OUZ_A_C3DA999_1
(ESTROGEN RECEPTOR)		 3qk9 MITOCHONDRIAL IMPORT
INNER MEMBRANE
TRANSLOCASE SUBUNIT
TIM44
(Saccharomyces
cerevisiae) 		4 / 6 ALA A 371
ASP A 345
GLU A 373
ARG A 424
 None
 1.44A 2ouzA-3qk9A:
undetectable		 2ouzA-3qk9A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_B_ACHB1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3qk9 MITOCHONDRIAL IMPORT
INNER MEMBRANE
TRANSLOCASE SUBUNIT
TIM44
(Saccharomyces
cerevisiae) 		4 / 7 TYR A 305
VAL A 423
TYR A 325
ILE A 419
 None
 1.24A 2xz5B-3qk9A:
undetectable
2xz5E-3qk9A:
undetectable		 2xz5B-3qk9A:
21.31
2xz5E-3qk9A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_C_ACHC1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3qk9 MITOCHONDRIAL IMPORT
INNER MEMBRANE
TRANSLOCASE SUBUNIT
TIM44
(Saccharomyces
cerevisiae) 		4 / 8 ILE A 419
TYR A 305
VAL A 423
TYR A 325
 None
 1.27A 2xz5A-3qk9A:
undetectable
2xz5C-3qk9A:
undetectable		 2xz5A-3qk9A:
21.31
2xz5C-3qk9A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3qk9 MITOCHONDRIAL IMPORT
INNER MEMBRANE
TRANSLOCASE SUBUNIT
TIM44
(Saccharomyces
cerevisiae) 		4 / 8 ILE A 419
TYR A 305
VAL A 423
TYR A 325
 None
 1.27A 2xz5C-3qk9A:
undetectable
2xz5D-3qk9A:
undetectable		 2xz5C-3qk9A:
21.31
2xz5D-3qk9A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_E_ACHE1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3qk9 MITOCHONDRIAL IMPORT
INNER MEMBRANE
TRANSLOCASE SUBUNIT
TIM44
(Saccharomyces
cerevisiae) 		4 / 7 ILE A 419
TYR A 305
VAL A 423
TYR A 325
 None
 1.25A 2xz5D-3qk9A:
undetectable
2xz5E-3qk9A:
undetectable		 2xz5D-3qk9A:
21.31
2xz5E-3qk9A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA2_0
(FERROCHELATASE)		 3qk9 MITOCHONDRIAL IMPORT
INNER MEMBRANE
TRANSLOCASE SUBUNIT
TIM44
(Saccharomyces
cerevisiae) 		4 / 6 MET A 395
ARG A 294
PRO A 249
GLY A 368
 None
 1.46A 3aqiA-3qk9A:
undetectable		 3aqiA-3qk9A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB4_0
(FERROCHELATASE)		 3qk9 MITOCHONDRIAL IMPORT
INNER MEMBRANE
TRANSLOCASE SUBUNIT
TIM44
(Saccharomyces
cerevisiae) 		4 / 6 MET A 395
ARG A 294
PRO A 249
GLY A 368
 None
 1.45A 3aqiB-3qk9A:
undetectable		 3aqiB-3qk9A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3qk9 MITOCHONDRIAL IMPORT
INNER MEMBRANE
TRANSLOCASE SUBUNIT
TIM44
(Saccharomyces
cerevisiae) 		5 / 12 VAL A 364
PHE A 289
VAL A 298
LEU A 302
ILE A 297
 None
 1.35A 3elzC-3qk9A:
undetectable		 3elzC-3qk9A:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OI8_A_ADNA2_1
(UNCHARACTERIZED
PROTEIN)		 3qk9 MITOCHONDRIAL IMPORT
INNER MEMBRANE
TRANSLOCASE SUBUNIT
TIM44
(Saccharomyces
cerevisiae) 		4 / 6 ILE A 257
ASN A 259
PRO A 359
LEU A 357
 None
 1.27A 3oi8A-3qk9A:
undetectable		 3oi8A-3qk9A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_2
(ANDROGEN RECEPTOR)		 3qk9 MITOCHONDRIAL IMPORT
INNER MEMBRANE
TRANSLOCASE SUBUNIT
TIM44
(Saccharomyces
cerevisiae) 		4 / 6 MET A 254
ILE A 301
ILE A 297
VAL A 298
 None
 0.99A 4olmA-3qk9A:
undetectable		 4olmA-3qk9A:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_A_MMZA503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		 3qk9 MITOCHONDRIAL IMPORT
INNER MEMBRANE
TRANSLOCASE SUBUNIT
TIM44
(Saccharomyces
cerevisiae) 		3 / 3 ASN A 248
SER A 397
SER A 427
 None
 0.73A 5gsnA-3qk9A:
undetectable		 5gsnA-3qk9A:
19.51