SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qkc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSG_B_MK1B902_1
(HIV-1 PROTEASE)		 3qkc GERANYL DIPHOSPHATE
SYNTHASE SMALL
SUBUNIT
(Antirrhinum
majus) 		5 / 10 LEU B 183
ALA B  81
VAL B 154
VAL B 147
ILE B 153
 None
 0.95A 1hsgA-3qkcB:
undetectable		 1hsgA-3qkcB:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4P_A_TPVA300_2
(PROTEASE)		 3qkc GERANYL DIPHOSPHATE
SYNTHASE SMALL
SUBUNIT
(Antirrhinum
majus) 		5 / 9 LEU B 183
VAL B 154
ILE B 115
VAL B 147
ILE B 153
 None
 0.83A 2o4pB-3qkcB:
undetectable		 2o4pB-3qkcB:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 3qkc GERANYL DIPHOSPHATE
SYNTHASE SMALL
SUBUNIT
(Antirrhinum
majus) 		5 / 12 LEU B 183
VAL B 154
ILE B 115
VAL B 147
ILE B 153
 None
 0.82A 2pynA-3qkcB:
undetectable		 2pynA-3qkcB:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q5K_A_AB1A201_1
(PROTEASE)		 3qkc GERANYL DIPHOSPHATE
SYNTHASE SMALL
SUBUNIT
(Antirrhinum
majus) 		5 / 9 VAL B 154
GLY B 112
ILE B 115
VAL B 147
ILE B 153
 None
 0.78A 2q5kA-3qkcB:
undetectable		 2q5kA-3qkcB:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_3
(PROTEASE RETROPEPSIN)		 3qkc GERANYL DIPHOSPHATE
SYNTHASE SMALL
SUBUNIT
(Antirrhinum
majus) 		5 / 12 LEU B 183
VAL B 154
ILE B 115
VAL B 147
ILE B 153
 None
 0.84A 2q64B-3qkcB:
undetectable		 2q64B-3qkcB:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 3qkc GERANYL DIPHOSPHATE
SYNTHASE SMALL
SUBUNIT
(Antirrhinum
majus) 		5 / 12 LEU B 183
VAL B 154
ILE B 115
VAL B 147
ILE B 153
 None
 0.81A 2qakB-3qkcB:
undetectable		 2qakB-3qkcB:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_A_IBPA1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 3qkc GERANYL DIPHOSPHATE
SYNTHASE SMALL
SUBUNIT
(Antirrhinum
majus) 		4 / 7 ILE B 230
LEU B 233
GLY B 213
GLY B 217
 None
 0.75A 2wd9A-3qkcB:
undetectable		 2wd9A-3qkcB:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_B_IBPB1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 3qkc GERANYL DIPHOSPHATE
SYNTHASE SMALL
SUBUNIT
(Antirrhinum
majus) 		4 / 8 ILE B 230
LEU B 233
GLY B 213
GLY B 217
 None
 0.77A 2wd9B-3qkcB:
undetectable		 2wd9B-3qkcB:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_1
(PROTEASE
(RETROPEPSIN))		 3qkc GERANYL DIPHOSPHATE
SYNTHASE SMALL
SUBUNIT
(Antirrhinum
majus) 		5 / 12 LEU B 183
VAL B 154
ILE B 115
VAL B 147
ILE B 153
 None
 0.88A 3bvbA-3qkcB:
undetectable		 3bvbA-3qkcB:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_2
(PROTEASE
(RETROPEPSIN))		 3qkc GERANYL DIPHOSPHATE
SYNTHASE SMALL
SUBUNIT
(Antirrhinum
majus) 		5 / 12 LEU B 183
VAL B 154
ILE B 115
VAL B 147
ILE B 153
 None
 0.88A 3bvbB-3qkcB:
undetectable		 3bvbB-3qkcB:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM3_B_478B200_1
(PROTEASE)		 3qkc GERANYL DIPHOSPHATE
SYNTHASE SMALL
SUBUNIT
(Antirrhinum
majus) 		5 / 10 LEU B 183
ALA B  81
VAL B 154
VAL B 147
ILE B 153
 None
 0.86A 3em3A-3qkcB:
undetectable		 3em3A-3qkcB:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM3_B_478B200_2
(PROTEASE)		 3qkc GERANYL DIPHOSPHATE
SYNTHASE SMALL
SUBUNIT
(Antirrhinum
majus) 		5 / 10 LEU B 183
ALA B  81
VAL B 154
VAL B 147
ILE B 153
 None
 0.92A 3em3B-3qkcB:
undetectable		 3em3B-3qkcB:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_1
(GAG-POL POLYPROTEIN)		 3qkc GERANYL DIPHOSPHATE
SYNTHASE SMALL
SUBUNIT
(Antirrhinum
majus) 		5 / 12 LEU B 183
VAL B 154
ILE B 115
VAL B 147
ILE B 153
 None
 0.84A 3jvyA-3qkcB:
undetectable		 3jvyA-3qkcB:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_2
(HIV-1 PROTEASE)		 3qkc GERANYL DIPHOSPHATE
SYNTHASE SMALL
SUBUNIT
(Antirrhinum
majus) 		5 / 11 VAL B 154
GLY B 112
ILE B 115
VAL B 147
ILE B 153
 None
 0.95A 3lzvB-3qkcB:
undetectable		 3lzvB-3qkcB:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU6_B_478B401_1
(PROTEASE)		 3qkc GERANYL DIPHOSPHATE
SYNTHASE SMALL
SUBUNIT
(Antirrhinum
majus) 		5 / 10 VAL B 154
GLY B 112
ILE B 115
VAL B 147
ILE B 153
 None
 0.83A 3nu6A-3qkcB:
undetectable		 3nu6A-3qkcB:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_D_017D200_2
(HIV-1 PROTEASE)		 3qkc GERANYL DIPHOSPHATE
SYNTHASE SMALL
SUBUNIT
(Antirrhinum
majus) 		5 / 10 LEU B 183
ALA B  81
VAL B 154
VAL B 147
ILE B 153
 None
 0.91A 3oxwD-3qkcB:
undetectable		 3oxwD-3qkcB:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OY4_B_017B200_1
(HIV-1 PROTEASE)		 3qkc GERANYL DIPHOSPHATE
SYNTHASE SMALL
SUBUNIT
(Antirrhinum
majus) 		5 / 11 LEU B 183
VAL B 154
ILE B 115
VAL B 147
ILE B 153
 None
 0.95A 3oy4A-3qkcB:
undetectable		 3oy4A-3qkcB:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQE_B_017B101_1
(ASPARTYL PROTEASE)		 3qkc GERANYL DIPHOSPHATE
SYNTHASE SMALL
SUBUNIT
(Antirrhinum
majus) 		5 / 11 LEU B 183
VAL B 154
ILE B 115
VAL B 147
ILE B 153
 None
 0.96A 4dqeA-3qkcB:
undetectable		 4dqeA-3qkcB:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_B_017B101_1
(PROTEASE)		 3qkc GERANYL DIPHOSPHATE
SYNTHASE SMALL
SUBUNIT
(Antirrhinum
majus) 		5 / 11 LEU B 183
VAL B 154
GLY B 112
ILE B 115
ILE B 153
 None
 0.98A 4njtA-3qkcB:
undetectable		 4njtA-3qkcB:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QGI_A_ROCA101_2
(PROTEASE)		 3qkc GERANYL DIPHOSPHATE
SYNTHASE SMALL
SUBUNIT
(Antirrhinum
majus) 		5 / 11 LEU B 183
VAL B 154
ILE B 115
VAL B 147
ILE B 153
 None
 0.85A 4qgiB-3qkcB:
undetectable		 4qgiB-3qkcB:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_C_RTLC201_0
(RETINOL-BINDING
PROTEIN 2)		 3qkc GERANYL DIPHOSPHATE
SYNTHASE SMALL
SUBUNIT
(Antirrhinum
majus) 		5 / 12 MET B 148
ILE B 153
ALA B  80
LEU B 183
LEU B 144
 None
 0.91A 4qzuC-3qkcB:
undetectable		 4qzuC-3qkcB:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_B_478B101_1
(HIV-1 PROTEASE)		 3qkc GERANYL DIPHOSPHATE
SYNTHASE SMALL
SUBUNIT
(Antirrhinum
majus) 		5 / 11 LEU B 183
VAL B 154
GLY B 112
ILE B 115
ILE B 153
 None
 0.93A 4rvjA-3qkcB:
undetectable		 4rvjA-3qkcB:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_D_478D101_1
(HIV-1 PROTEASE)		 3qkc GERANYL DIPHOSPHATE
SYNTHASE SMALL
SUBUNIT
(Antirrhinum
majus) 		5 / 11 LEU B 183
VAL B 154
GLY B 112
ILE B 115
ILE B 153
 None
 0.91A 4rvjC-3qkcB:
undetectable		 4rvjC-3qkcB:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE2_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3qkc GERANYL DIPHOSPHATE
SYNTHASE SMALL
SUBUNIT
(Antirrhinum
majus) 		5 / 12 GLY B 217
LEU B 258
LEU B  52
HIS B 184
THR B 214
 None
 1.06A 4ze2A-3qkcB:
1.0		 4ze2A-3qkcB:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EQB_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3qkc GERANYL DIPHOSPHATE
SYNTHASE SMALL
SUBUNIT
(Antirrhinum
majus) 		5 / 12 GLY B 217
GLY B 245
LEU B  52
HIS B 184
THR B 214
 None
 1.11A 5eqbA-3qkcB:
undetectable		 5eqbA-3qkcB:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMD_C_6UBC1304_1
(ION TRANSPORT
PROTEIN)		 3qkc GERANYL DIPHOSPHATE
SYNTHASE SMALL
SUBUNIT
(Antirrhinum
majus) 		4 / 5 TYR B  20
ILE B  17
LEU B 120
GLY B 119
 None
 0.93A 5kmdC-3qkcB:
undetectable
5kmdD-3qkcB:
2.3		 5kmdC-3qkcB:
20.82
5kmdD-3qkcB:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3qkc GERANYL DIPHOSPHATE
SYNTHASE SMALL
SUBUNIT
(Antirrhinum
majus) 		4 / 5 LEU B 233
LYS B 234
ALA B 237
LEU B 258
 None
 0.83A 5vkqA-3qkcB:
undetectable
5vkqD-3qkcB:
undetectable		 5vkqA-3qkcB:
9.92
5vkqD-3qkcB:
9.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3qkc GERANYL DIPHOSPHATE
SYNTHASE SMALL
SUBUNIT
(Antirrhinum
majus) 		4 / 5 LEU B 258
LEU B 233
LYS B 234
ALA B 237
 None
 0.82A 5vkqA-3qkcB:
undetectable
5vkqB-3qkcB:
undetectable		 5vkqA-3qkcB:
9.92
5vkqB-3qkcB:
9.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3qkc GERANYL DIPHOSPHATE
SYNTHASE SMALL
SUBUNIT
(Antirrhinum
majus) 		4 / 5 LEU B 258
LEU B 233
LYS B 234
ALA B 237
 None
 0.80A 5vkqB-3qkcB:
undetectable
5vkqC-3qkcB:
undetectable		 5vkqB-3qkcB:
9.92
5vkqC-3qkcB:
9.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3qkc GERANYL DIPHOSPHATE
SYNTHASE SMALL
SUBUNIT
(Antirrhinum
majus) 		4 / 5 LEU B 258
LEU B 233
LYS B 234
ALA B 237
 None
 0.83A 5vkqC-3qkcB:
undetectable
5vkqD-3qkcB:
undetectable		 5vkqC-3qkcB:
9.92
5vkqD-3qkcB:
9.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_C_CVIC301_0
(REGULATORY PROTEIN
TETR)		 3qkc GERANYL DIPHOSPHATE
SYNTHASE SMALL
SUBUNIT
(Antirrhinum
majus) 		5 / 12 MET B  68
ALA B  72
GLU B 143
LEU B 194
TYR B   9
 None
 1.37A 5vlmC-3qkcB:
2.4		 5vlmC-3qkcB:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_0
(REGULATORY PROTEIN
TETR)		 3qkc GERANYL DIPHOSPHATE
SYNTHASE SMALL
SUBUNIT
(Antirrhinum
majus) 		5 / 12 MET B 123
ALA B  72
LEU B 144
VAL B  54
CYH B  57
 None
 1.44A 5vlmE-3qkcB:
2.0		 5vlmE-3qkcB:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW4_A_SAMA302_0
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)		 3qkc GERANYL DIPHOSPHATE
SYNTHASE SMALL
SUBUNIT
(Antirrhinum
majus) 		5 / 12 MET B  77
GLY B 187
ALA B  49
ALA B 192
ALA B  67
 None
 0.96A 5zw4A-3qkcB:
undetectable		 5zw4A-3qkcB:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIL_B_TPVB201_1
(HIV-1 PROTEASE)		 3qkc GERANYL DIPHOSPHATE
SYNTHASE SMALL
SUBUNIT
(Antirrhinum
majus) 		5 / 12 LEU B 183
VAL B 154
ILE B 115
VAL B 147
ILE B 153
 None
 0.82A 6dilB-3qkcB:
undetectable		 6dilB-3qkcB:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ2_B_AB1B201_0
(HIV-1 PROTEASE)		 3qkc GERANYL DIPHOSPHATE
SYNTHASE SMALL
SUBUNIT
(Antirrhinum
majus) 		5 / 10 VAL B 154
GLY B 112
ILE B 115
VAL B 147
ILE B 153
 None
 0.89A 6dj2A-3qkcB:
undetectable		 6dj2A-3qkcB:
13.60