SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qki'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_2
(PROTEIN (ADENOSINE
KINASE))		 3qki GLUCOSE-6-PHOSPHATE
ISOMERASE
(Plasmodium
falciparum) 		3 / 3 LEU A 503
SER A 433
ASN A 176
 None
 0.84A 1bx4A-3qkiA:
undetectable		 1bx4A-3qkiA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		 3qki GLUCOSE-6-PHOSPHATE
ISOMERASE
(Plasmodium
falciparum) 		4 / 7 VAL A 291
VAL A 267
LEU A 319
LEU A  98
 None
 0.89A 1cqpA-3qkiA:
undetectable
1cqpB-3qkiA:
undetectable		 1cqpA-3qkiA:
15.49
1cqpB-3qkiA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVT_A_FLPA125_1
(TRANSTHYRETIN)		 3qki GLUCOSE-6-PHOSPHATE
ISOMERASE
(Plasmodium
falciparum) 		4 / 8 LEU A  60
LEU A  63
LEU A   8
SER A  10
 None
 0.93A 1dvtA-3qkiA:
undetectable
1dvtB-3qkiA:
undetectable		 1dvtA-3qkiA:
11.49
1dvtB-3qkiA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SKX_A_RFPA1_1
(ORPHAN NUCLEAR
RECEPTOR PXR)		 3qki GLUCOSE-6-PHOSPHATE
ISOMERASE
(Plasmodium
falciparum) 		5 / 12 SER A 378
CYH A 398
GLN A 399
ILE A 428
PHE A 370
 None
 1.41A 1skxA-3qkiA:
undetectable		 1skxA-3qkiA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3qki GLUCOSE-6-PHOSPHATE
ISOMERASE
(Plasmodium
falciparum) 		4 / 7 SER A 513
ARG A  99
PHE A 318
THR A 298
 None
 1.15A 2f78A-3qkiA:
undetectable		 2f78A-3qkiA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_F_TACF3888_1
(ELONGATION FACTOR
EF-TU)		 3qki GLUCOSE-6-PHOSPHATE
ISOMERASE
(Plasmodium
falciparum) 		4 / 7 SER A 299
SER A 300
VAL A 124
LEU A 271
 None
 1.03A 2hdnE-3qkiA:
undetectable
2hdnF-3qkiA:
undetectable
2hdnH-3qkiA:
3.2		 2hdnE-3qkiA:
4.58
2hdnF-3qkiA:
18.77
2hdnH-3qkiA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_1
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 3qki GLUCOSE-6-PHOSPHATE
ISOMERASE
(Plasmodium
falciparum) 		5 / 12 THR A 507
ALA A 169
PHE A 165
ILE A 428
LEU A 450
 None
 1.20A 2nyrA-3qkiA:
3.6		 2nyrA-3qkiA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_3
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 3qki GLUCOSE-6-PHOSPHATE
ISOMERASE
(Plasmodium
falciparum) 		5 / 12 ILE A 374
HIS A 373
PHE A 295
GLY A 293
LEU A 306
 None
 1.48A 2nyrB-3qkiA:
2.8		 2nyrB-3qkiA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMZ_A_LDPA501_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)		 3qki GLUCOSE-6-PHOSPHATE
ISOMERASE
(Plasmodium
falciparum) 		4 / 7 GLY A 406
PHE A 413
ILE A 417
PHE A 402
 None
 0.92A 2qmzA-3qkiA:
2.2
2qmzB-3qkiA:
2.4		 2qmzA-3qkiA:
17.06
2qmzB-3qkiA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WX2_B_TPFB1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3qki GLUCOSE-6-PHOSPHATE
ISOMERASE
(Plasmodium
falciparum) 		4 / 8 TYR A 172
PHE A 310
TYR A 175
ALA A 309
 None
 0.95A 2wx2B-3qkiA:
undetectable		 2wx2B-3qkiA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_X_CPFX1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 3qki GLUCOSE-6-PHOSPHATE
ISOMERASE
(Plasmodium
falciparum) 		4 / 4 ARG A 294
GLY A 158
GLU A 380
SER A 300
 None
 1.39A 2xctS-3qkiA:
undetectable
2xctU-3qkiA:
undetectable		 2xctS-3qkiA:
21.53
2xctU-3qkiA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI9_X_SAMX501_0
(UPF0217 PROTEIN
MJ1640)		 3qki GLUCOSE-6-PHOSPHATE
ISOMERASE
(Plasmodium
falciparum) 		5 / 9 LEU A 205
ILE A 154
GLY A 155
GLU A 238
LEU A 241
 None
 1.00A 3ai9X-3qkiA:
undetectable		 3ai9X-3qkiA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F33_A_PFLA2001_1
(FERRITIN LIGHT CHAIN)		 3qki GLUCOSE-6-PHOSPHATE
ISOMERASE
(Plasmodium
falciparum) 		4 / 6 LEU A   8
SER A  10
TYR A  11
LEU A  14
 None
 1.05A 3f33A-3qkiA:
undetectable		 3f33A-3qkiA:
14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I9J_B_NCAB302_0
(ADP-RIBOSYL CYCLASE)		 3qki GLUCOSE-6-PHOSPHATE
ISOMERASE
(Plasmodium
falciparum) 		4 / 6 LEU A 377
GLU A 516
SER A 381
PHE A 531
 None
 1.40A 3i9jB-3qkiA:
undetectable		 3i9jB-3qkiA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_A_ACRA720_1
(ALPHA-AMYLASE, SUSG)		 3qki GLUCOSE-6-PHOSPHATE
ISOMERASE
(Plasmodium
falciparum) 		4 / 7 TYR A  29
GLU A  20
LEU A  26
ASN A 492
 None
 1.42A 3k8mA-3qkiA:
undetectable		 3k8mA-3qkiA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LK0_D_Z80D92_1
(PROTEIN S100-B)		 3qki GLUCOSE-6-PHOSPHATE
ISOMERASE
(Plasmodium
falciparum) 		3 / 3 HIS A 432
PHE A 454
PHE A 455
 None
 0.75A 3lk0D-3qkiA:
0.8		 3lk0D-3qkiA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U6T_A_KANA4699_1
(RIBOSOME
INACTIVATING PROTEIN)		 3qki GLUCOSE-6-PHOSPHATE
ISOMERASE
(Plasmodium
falciparum) 		5 / 10 SER A 350
ASN A 396
TYR A 395
ILE A   5
GLU A   4
 None
 1.45A 3u6tA-3qkiA:
undetectable		 3u6tA-3qkiA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD393_1
(TETX2 PROTEIN)		 3qki GLUCOSE-6-PHOSPHATE
ISOMERASE
(Plasmodium
falciparum) 		4 / 5 ILE A 360
ILE A 519
TYR A 515
GLU A 516
 None
 1.19A 4a99D-3qkiA:
undetectable		 4a99D-3qkiA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BUP_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 3qki GLUCOSE-6-PHOSPHATE
ISOMERASE
(Plasmodium
falciparum) 		3 / 3 HIS A 122
GLU A 103
ASN A 320
 None
 0.94A 4bupB-3qkiA:
undetectable		 4bupB-3qkiA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BUP_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 3qki GLUCOSE-6-PHOSPHATE
ISOMERASE
(Plasmodium
falciparum) 		3 / 3 HIS A 122
GLU A 119
ASN A 106
 None
 0.87A 4bupB-3qkiA:
undetectable		 4bupB-3qkiA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_1
(ANDROGEN RECEPTOR)		 3qki GLUCOSE-6-PHOSPHATE
ISOMERASE
(Plasmodium
falciparum) 		5 / 12 LEU A 427
GLY A 406
GLN A 410
LEU A 450
MET A 451
 None
 1.33A 4olmA-3qkiA:
undetectable		 4olmA-3qkiA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_B_1LDB501_0
(CYTOSINE DEAMINASE)		 3qki GLUCOSE-6-PHOSPHATE
ISOMERASE
(Plasmodium
falciparum) 		5 / 12 LEU A 342
PHE A 370
ILE A 428
GLU A 426
SER A 378
 None
 1.06A 4r88B-3qkiA:
undetectable		 4r88B-3qkiA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_C_1LDC501_0
(CYTOSINE DEAMINASE)		 3qki GLUCOSE-6-PHOSPHATE
ISOMERASE
(Plasmodium
falciparum) 		5 / 12 LEU A 342
PHE A 370
ILE A 428
GLU A 426
SER A 378
 None
 1.04A 4r88C-3qkiA:
undetectable		 4r88C-3qkiA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_E_1LDE501_0
(CYTOSINE DEAMINASE)		 3qki GLUCOSE-6-PHOSPHATE
ISOMERASE
(Plasmodium
falciparum) 		5 / 12 LEU A 342
PHE A 370
ILE A 428
GLU A 426
SER A 378
 None
 1.02A 4r88E-3qkiA:
undetectable		 4r88E-3qkiA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_F_1LDF502_0
(CYTOSINE DEAMINASE)		 3qki GLUCOSE-6-PHOSPHATE
ISOMERASE
(Plasmodium
falciparum) 		5 / 12 LEU A 342
PHE A 370
ILE A 428
GLU A 426
SER A 378
 None
 1.01A 4r88F-3qkiA:
undetectable		 4r88F-3qkiA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YSH_B_GLYB401_0
(GLYCINE OXIDASE)		 3qki GLUCOSE-6-PHOSPHATE
ISOMERASE
(Plasmodium
falciparum) 		4 / 6 PHE A 505
LYS A 313
GLY A 311
ALA A 309
 None
 1.03A 4yshB-3qkiA:
undetectable		 4yshB-3qkiA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_A_ACTA708_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 3qki GLUCOSE-6-PHOSPHATE
ISOMERASE
(Plasmodium
falciparum) 		3 / 3 GLY A 292
GLY A 293
GLN A 533
 None
 0.37A 5imsA-3qkiA:
2.6		 5imsA-3qkiA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L2T_A_6ZZA900_2
(CYCLIN-DEPENDENT
KINASE 6)		 3qki GLUCOSE-6-PHOSPHATE
ISOMERASE
(Plasmodium
falciparum) 		3 / 3 LYS A  27
GLN A 419
ASN A 490
 None
 0.98A 5l2tA-3qkiA:
undetectable		 5l2tA-3qkiA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_F_Z80F401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3qki GLUCOSE-6-PHOSPHATE
ISOMERASE
(Plasmodium
falciparum) 		5 / 10 ILE A 303
ILE A 128
PHE A 285
ASP A 133
ILE A 308
 None
 1.20A 5lg3F-3qkiA:
undetectable		 5lg3F-3qkiA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_G_Z80G401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3qki GLUCOSE-6-PHOSPHATE
ISOMERASE
(Plasmodium
falciparum) 		5 / 10 ILE A 303
ILE A 128
PHE A 285
ASP A 133
ILE A 308
 None
 1.21A 5lg3G-3qkiA:
undetectable		 5lg3G-3qkiA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_H_Z80H401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3qki GLUCOSE-6-PHOSPHATE
ISOMERASE
(Plasmodium
falciparum) 		5 / 10 ILE A 303
ILE A 128
PHE A 285
ASP A 133
ILE A 308
 None
 1.19A 5lg3H-3qkiA:
undetectable		 5lg3H-3qkiA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_J_Z80J401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3qki GLUCOSE-6-PHOSPHATE
ISOMERASE
(Plasmodium
falciparum) 		5 / 12 ILE A 303
ILE A 128
PHE A 285
ASP A 133
ILE A 308
 None
 1.18A 5lg3J-3qkiA:
undetectable		 5lg3J-3qkiA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_A_SAMA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		 3qki GLUCOSE-6-PHOSPHATE
ISOMERASE
(Plasmodium
falciparum) 		3 / 3 HIS A 122
GLU A 103
ASN A 320
 None
 0.91A 5wbvA-3qkiA:
undetectable		 5wbvA-3qkiA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_A_SAMA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		 3qki GLUCOSE-6-PHOSPHATE
ISOMERASE
(Plasmodium
falciparum) 		3 / 3 HIS A 122
GLU A 119
ASN A 106
 None
 0.74A 5wbvA-3qkiA:
undetectable		 5wbvA-3qkiA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_B_SAMB402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		 3qki GLUCOSE-6-PHOSPHATE
ISOMERASE
(Plasmodium
falciparum) 		3 / 3 HIS A 122
GLU A 103
ASN A 320
 None
 0.91A 5wbvB-3qkiA:
3.0		 5wbvB-3qkiA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_B_SAMB402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		 3qki GLUCOSE-6-PHOSPHATE
ISOMERASE
(Plasmodium
falciparum) 		3 / 3 HIS A 122
GLU A 119
ASN A 106
 None
 0.74A 5wbvB-3qkiA:
3.0		 5wbvB-3qkiA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_E_GBME2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 3qki GLUCOSE-6-PHOSPHATE
ISOMERASE
(Plasmodium
falciparum) 		3 / 3 LEU A 161
THR A 239
ASN A 242
 None
 0.66A 6baaE-3qkiA:
undetectable		 6baaE-3qkiA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_F_GBMF2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 3qki GLUCOSE-6-PHOSPHATE
ISOMERASE
(Plasmodium
falciparum) 		3 / 3 LEU A 161
THR A 239
ASN A 242
 None
 0.65A 6baaF-3qkiA:
undetectable		 6baaF-3qkiA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_G_GBMG2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 3qki GLUCOSE-6-PHOSPHATE
ISOMERASE
(Plasmodium
falciparum) 		3 / 3 LEU A 161
THR A 239
ASN A 242
 None
 0.66A 6baaG-3qkiA:
undetectable		 6baaG-3qkiA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_H_GBMH2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 3qki GLUCOSE-6-PHOSPHATE
ISOMERASE
(Plasmodium
falciparum) 		3 / 3 LEU A 161
THR A 239
ASN A 242
 None
 0.66A 6baaH-3qkiA:
undetectable		 6baaH-3qkiA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EF6_A_ACTA405_0
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 3qki GLUCOSE-6-PHOSPHATE
ISOMERASE
(Plasmodium
falciparum) 		4 / 6 ARG A 518
PRO A 424
GLN A 399
ILE A 360
 None
 1.14A 6ef6A-3qkiA:
undetectable		 6ef6A-3qkiA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_1
(-)		 3qki GLUCOSE-6-PHOSPHATE
ISOMERASE
(Plasmodium
falciparum) 		5 / 12 VAL A 297
TYR A 312
VAL A 166
CYH A 508
GLY A 509
 None
 1.43A 6gngB-3qkiA:
2.7		 6gngB-3qkiA:
22.70