SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qkx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QAB_F_RTLF2_0
(PROTEIN (RETINOL
BINDING PROTEIN))		 3qkx UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR HI_0893
(Haemophilus
influenzae) 		5 / 12 ALA A  40
ALA A  34
GLY A  42
TYR A  45
LEU A  54
 None
 1.21A 1qabF-3qkxA:
undetectable		 1qabF-3qkxA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_A_HSMA401_1
(NITROPHORIN 1)		 3qkx UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR HI_0893
(Haemophilus
influenzae) 		4 / 4 ASP A 145
LEU A 150
LEU A 147
LEU A 149
 None
 1.38A 1u18A-3qkxA:
undetectable		 1u18A-3qkxA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_A_FUAA2002_1
(SERUM ALBUMIN)		 3qkx UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR HI_0893
(Haemophilus
influenzae) 		4 / 9 ILE A 101
PHE A  58
ALA A  59
VAL A  62
 None
 0.67A 2vufA-3qkxA:
undetectable		 2vufA-3qkxA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_A_TOPA200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 3qkx UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR HI_0893
(Haemophilus
influenzae) 		5 / 10 MET A  65
ALA A 155
ILE A 156
LEU A 105
PHE A  66
 None
 1.10A 3fl9A-3qkxA:
undetectable		 3fl9A-3qkxA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_F_TOPF200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 3qkx UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR HI_0893
(Haemophilus
influenzae) 		5 / 10 MET A  65
ALA A 155
ILE A 156
LEU A 105
PHE A  66
 None
 1.11A 3fl9F-3qkxA:
undetectable		 3fl9F-3qkxA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DM8_B_REAB1501_1
(RETINOIC ACID
RECEPTOR BETA)		 3qkx UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR HI_0893
(Haemophilus
influenzae) 		5 / 12 ALA A 159
LEU A 105
LEU A 102
ILE A 101
LEU A 152
 None
 1.08A 4dm8B-3qkxA:
undetectable		 4dm8B-3qkxA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3qkx UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR HI_0893
(Haemophilus
influenzae) 		4 / 8 ASP A 127
CYH A 118
ASP A 145
GLU A 144
 EDO  A 202 (-3.6A)
None
None
None
 1.17A 4feuF-3qkxA:
undetectable		 4feuF-3qkxA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3qkx UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR HI_0893
(Haemophilus
influenzae) 		4 / 7 ASP A 161
THR A 154
LEU A 102
GLN A 107
 None
 1.02A 4ib4A-3qkxA:
undetectable		 4ib4A-3qkxA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 3qkx UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR HI_0893
(Haemophilus
influenzae) 		5 / 12 MET A  30
ILE A  44
GLN A 107
LEU A  25
LEU A  28
 None
 1.46A 4qztA-3qkxA:
undetectable		 4qztA-3qkxA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 3qkx UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR HI_0893
(Haemophilus
influenzae) 		5 / 12 MET A  30
ILE A  44
VAL A  62
LEU A  25
LEU A  28
 None
 1.38A 4qztA-3qkxA:
undetectable		 4qztA-3qkxA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_B_VORB590_1
(14-ALPHA STEROL
DEMETHYLASE)		 3qkx UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR HI_0893
(Haemophilus
influenzae) 		4 / 7 ALA A   9
ILE A  44
LEU A  54
PHE A  48
 None
 1.00A 4uymB-3qkxA:
undetectable		 4uymB-3qkxA:
14.95