SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qky'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_A_NCAA1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 3qky OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFIO
(Rhodothermus
marinus) 		4 / 7 SER A  92
ARG A  65
GLN A  99
GLU A  95
 None
 1.33A 2c8aA-3qkyA:
undetectable		 2c8aA-3qkyA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLK_B_SPMB1302_1
(ATP-SENSITIVE INWARD
RECTIFIER POTASSIUM
CHANNEL 10)		 3qky OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFIO
(Rhodothermus
marinus) 		4 / 4 ALA A  41
TYR A  45
ALA A  73
TYR A  76
 None
 1.25A 2wlkA-3qkyA:
undetectable
2wlkB-3qkyA:
undetectable		 2wlkA-3qkyA:
21.84
2wlkB-3qkyA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9F_F_LFXF0_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 3qky OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFIO
(Rhodothermus
marinus) 		4 / 5 SER A 247
ARG A 175
GLY A 209
GLU A 178
 None
 0.99A 3k9fA-3qkyA:
undetectable
3k9fB-3qkyA:
undetectable
3k9fC-3qkyA:
undetectable		 3k9fA-3qkyA:
20.59
3k9fB-3qkyA:
20.59
3k9fC-3qkyA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9F_H_LFXH0_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 3qky OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFIO
(Rhodothermus
marinus) 		4 / 6 SER A 247
ARG A 175
GLY A 209
GLU A 178
 None
 0.99A 3k9fA-3qkyA:
undetectable
3k9fB-3qkyA:
undetectable
3k9fD-3qkyA:
undetectable		 3k9fA-3qkyA:
20.59
3k9fB-3qkyA:
20.59
3k9fD-3qkyA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU9_B_SPMB700_1
(POLYAMINE OXIDASE)		 3qky OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFIO
(Rhodothermus
marinus) 		4 / 7 GLU A 113
TYR A  45
TYR A  76
PHE A  97
 None
 1.31A 3ku9B-3qkyA:
undetectable		 3ku9B-3qkyA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_I_ACHI323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 3qky OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFIO
(Rhodothermus
marinus) 		4 / 8 ILE A  98
GLU A 111
TYR A 146
PHE A 142
 None
 0.92A 3rqwI-3qkyA:
undetectable
3rqwJ-3qkyA:
undetectable		 3rqwI-3qkyA:
19.57
3rqwJ-3qkyA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3qky OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFIO
(Rhodothermus
marinus) 		4 / 7 ILE A  98
GLU A 111
TYR A 146
PHE A 142
 None
 0.86A 4a97H-3qkyA:
undetectable		 4a97H-3qkyA:
21.15