SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qlb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GX9_A_REAA1163_1
(BETA-LACTOGLOBULIN)		 3qlb ENANTIO-PYOCHELIN
RECEPTOR
(Pseudomonas
fluorescens) 		5 / 11 VAL A  68
ILE A  58
GLU A 123
ILE A 130
GLN A  66
 None
 1.34A 1gx9A-3qlbA:
undetectable		 1gx9A-3qlbA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_A_SAMA401_1
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 3qlb ENANTIO-PYOCHELIN
RECEPTOR
(Pseudomonas
fluorescens) 		4 / 4 HIS A 208
ASP A 173
SER A 171
ASP A 207
 None
 1.03A 1n2xA-3qlbA:
undetectable		 1n2xA-3qlbA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_1
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 3qlb ENANTIO-PYOCHELIN
RECEPTOR
(Pseudomonas
fluorescens) 		3 / 3 HIS A 304
ASP A 276
ASN A 310
 None
 0.79A 1wg8B-3qlbA:
undetectable		 1wg8B-3qlbA:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_D_TFPD207_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3qlb ENANTIO-PYOCHELIN
RECEPTOR
(Pseudomonas
fluorescens) 		4 / 8 SER A  38
LEU A 140
LEU A  75
SER A  54
 None
 0.93A 1wrlC-3qlbA:
undetectable
1wrlD-3qlbA:
undetectable		 1wrlC-3qlbA:
9.72
1wrlD-3qlbA:
9.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_A_IMNA379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3qlb ENANTIO-PYOCHELIN
RECEPTOR
(Pseudomonas
fluorescens) 		5 / 12 TYR A  77
THR A  78
VAL A 150
ILE A  58
VAL A  81
 None
 1.22A 1z9hA-3qlbA:
undetectable		 1z9hA-3qlbA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_B_IMNB381_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3qlb ENANTIO-PYOCHELIN
RECEPTOR
(Pseudomonas
fluorescens) 		5 / 12 TYR A  77
THR A  78
VAL A 150
ILE A  58
VAL A  81
 None
 1.22A 1z9hB-3qlbA:
undetectable		 1z9hB-3qlbA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_C_IMNC379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3qlb ENANTIO-PYOCHELIN
RECEPTOR
(Pseudomonas
fluorescens) 		5 / 12 TYR A  77
THR A  78
VAL A 150
ILE A  58
VAL A  81
 None
 1.22A 1z9hC-3qlbA:
undetectable		 1z9hC-3qlbA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_B_ERYB1399_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 3qlb ENANTIO-PYOCHELIN
RECEPTOR
(Pseudomonas
fluorescens) 		5 / 12 ASN A 151
VAL A 149
LEU A 358
TYR A 415
ASP A  45
 None
 1.44A 2iyfB-3qlbA:
undetectable		 2iyfB-3qlbA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_1
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 3qlb ENANTIO-PYOCHELIN
RECEPTOR
(Pseudomonas
fluorescens) 		3 / 3 GLN A 152
THR A  94
TRP A 119
 None
 1.17A 2rctA-3qlbA:
3.0		 2rctA-3qlbA:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLC_A_GLYA333_0
(CHOLOYLGLYCINE
HYDROLASE)		 3qlb ENANTIO-PYOCHELIN
RECEPTOR
(Pseudomonas
fluorescens) 		3 / 3 ASN A 310
ASN A 275
ARG A  91
 None
None
EFE  A 701 (-4.0A)
 0.92A 2rlcA-3qlbA:
undetectable		 2rlcA-3qlbA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_C_ZMRC1776_2
(NEURAMINIDASE A)		 3qlb ENANTIO-PYOCHELIN
RECEPTOR
(Pseudomonas
fluorescens) 		4 / 6 ARG A 263
ILE A 209
GLN A  90
TYR A 686
 None
 1.16A 2ya7C-3qlbA:
undetectable		 2ya7C-3qlbA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		 3qlb ENANTIO-PYOCHELIN
RECEPTOR
(Pseudomonas
fluorescens) 		4 / 6 TYR A 415
ALA A 416
LEU A 358
ALA A 344
 None
 0.88A 3b6hA-3qlbA:
undetectable		 3b6hA-3qlbA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH504_3
(PHOSPHOLIPASE A2)		 3qlb ENANTIO-PYOCHELIN
RECEPTOR
(Pseudomonas
fluorescens) 		5 / 11 VAL A 427
LEU A 428
ILE A 475
SER A 476
SER A 478
 None
 1.28A 3bjwH-3qlbA:
undetectable		 3bjwH-3qlbA:
9.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3qlb ENANTIO-PYOCHELIN
RECEPTOR
(Pseudomonas
fluorescens) 		5 / 12 ASN A 151
GLY A 110
VAL A  81
GLY A 148
ASN A 144
 None
 1.28A 3k13A-3qlbA:
undetectable		 3k13A-3qlbA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3qlb ENANTIO-PYOCHELIN
RECEPTOR
(Pseudomonas
fluorescens) 		5 / 12 ASN A 151
GLY A 110
VAL A  81
GLY A 148
ASN A 144
 None
 1.29A 3k13C-3qlbA:
undetectable		 3k13C-3qlbA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KIV_A_ACAA100_1
(APOLIPOPROTEIN)		 3qlb ENANTIO-PYOCHELIN
RECEPTOR
(Pseudomonas
fluorescens) 		4 / 7 ARG A 277
ASP A  93
PHE A 241
ARG A  91
 None
None
None
EFE  A 701 (-4.0A)
 1.35A 3kivA-3qlbA:
undetectable		 3kivA-3qlbA:
7.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KKZ_B_SAMB302_0
(UNCHARACTERIZED
PROTEIN Q5LES9)		 3qlb ENANTIO-PYOCHELIN
RECEPTOR
(Pseudomonas
fluorescens) 		5 / 12 GLY A 142
GLY A 148
GLY A 105
PHE A 100
ALA A 137
 None
 1.03A 3kkzB-3qlbA:
undetectable		 3kkzB-3qlbA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_3
(PROTEASE)		 3qlb ENANTIO-PYOCHELIN
RECEPTOR
(Pseudomonas
fluorescens) 		5 / 12 ARG A 436
ASP A 435
GLY A 142
GLY A 360
ILE A 361
 None
 0.90A 3ndtB-3qlbA:
undetectable		 3ndtB-3qlbA:
9.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_B_TCWB1126_1
(TRANSTHYRETIN)		 3qlb ENANTIO-PYOCHELIN
RECEPTOR
(Pseudomonas
fluorescens) 		4 / 7 LEU A 524
THR A 497
ALA A 499
SER A 478
 None
 0.95A 4d7bA-3qlbA:
undetectable		 4d7bA-3qlbA:
11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMC_A_29JA603_1
(TRANSPORTER)		 3qlb ENANTIO-PYOCHELIN
RECEPTOR
(Pseudomonas
fluorescens) 		5 / 10 ASP A 341
TYR A 415
GLY A 110
PHE A 141
GLY A 142
 None
 1.32A 4mmcA-3qlbA:
undetectable		 4mmcA-3qlbA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_B_29QB603_1
(TRANSPORTER)		 3qlb ENANTIO-PYOCHELIN
RECEPTOR
(Pseudomonas
fluorescens) 		5 / 9 ASP A 341
TYR A 415
GLY A 110
PHE A 141
GLY A 142
 None
 1.22A 4mmeB-3qlbA:
undetectable		 4mmeB-3qlbA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 3qlb ENANTIO-PYOCHELIN
RECEPTOR
(Pseudomonas
fluorescens) 		3 / 3 ASP A 362
ASN A 343
SER A 138
 None
 0.58A 4obwA-3qlbA:
undetectable		 4obwA-3qlbA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 3qlb ENANTIO-PYOCHELIN
RECEPTOR
(Pseudomonas
fluorescens) 		4 / 6 ASP A 564
ALA A  31
THR A  59
TYR A  33
 None
 1.45A 4w5qA-3qlbA:
undetectable		 4w5qA-3qlbA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 3qlb ENANTIO-PYOCHELIN
RECEPTOR
(Pseudomonas
fluorescens) 		4 / 6 ASP A 564
ALA A  31
THR A  59
TYR A  33
 None
 1.45A 4w5tA-3qlbA:
undetectable		 4w5tA-3qlbA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_G_MZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3qlb ENANTIO-PYOCHELIN
RECEPTOR
(Pseudomonas
fluorescens) 		5 / 12 VAL A 132
LYS A 134
VAL A 150
LEU A  75
ALA A  74
 None
 1.35A 4yhaG-3qlbA:
undetectable		 4yhaG-3qlbA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 3qlb ENANTIO-PYOCHELIN
RECEPTOR
(Pseudomonas
fluorescens) 		4 / 6 ASP A 564
ALA A  31
THR A  59
TYR A  33
 None
 1.44A 4z4cA-3qlbA:
undetectable		 4z4cA-3qlbA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3qlb ENANTIO-PYOCHELIN
RECEPTOR
(Pseudomonas
fluorescens) 		4 / 6 ASP A 564
ALA A  31
THR A  59
TYR A  33
 None
 1.46A 4z4fA-3qlbA:
undetectable		 4z4fA-3qlbA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 3qlb ENANTIO-PYOCHELIN
RECEPTOR
(Pseudomonas
fluorescens) 		4 / 5 ASP A 564
ALA A  31
THR A  59
TYR A  33
 None
 1.46A 4z4gA-3qlbA:
undetectable		 4z4gA-3qlbA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4H_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 3qlb ENANTIO-PYOCHELIN
RECEPTOR
(Pseudomonas
fluorescens) 		4 / 5 ASP A 564
ALA A  31
THR A  59
TYR A  33
 None
 1.44A 4z4hA-3qlbA:
0.0		 4z4hA-3qlbA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3qlb ENANTIO-PYOCHELIN
RECEPTOR
(Pseudomonas
fluorescens) 		4 / 6 ASP A 564
ALA A  31
THR A  59
TYR A  33
 None
 1.44A 4z4iA-3qlbA:
undetectable		 4z4iA-3qlbA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE1_A_X2NA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3qlb ENANTIO-PYOCHELIN
RECEPTOR
(Pseudomonas
fluorescens) 		4 / 5 VAL A 102
TYR A 494
PRO A 483
THR A 441
 None
 1.29A 4ze1A-3qlbA:
undetectable		 4ze1A-3qlbA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DB5_A_CYSA503_0
(CYSTEINE DESULFURASE)		 3qlb ENANTIO-PYOCHELIN
RECEPTOR
(Pseudomonas
fluorescens) 		4 / 8 ALA A 118
HIS A 304
ASN A 306
THR A 337
 None
 1.32A 5db5A-3qlbA:
undetectable
5db5B-3qlbA:
undetectable		 5db5A-3qlbA:
21.48
5db5B-3qlbA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWT_D_BEZD202_0
(PR 10 PROTEIN)		 3qlb ENANTIO-PYOCHELIN
RECEPTOR
(Pseudomonas
fluorescens) 		3 / 3 PHE A  92
ASP A  93
LYS A 121
 EFE  A 701 (-4.7A)
None
None
 0.77A 6awtD-3qlbA:
2.4		 6awtD-3qlbA:
12.09