SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qlj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZZ_A_ACTA421_0
(ACLACINOMYCIN-10-HYD
ROXYLASE)		 3qlj SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		4 / 8 GLY A  50
GLY A  49
LEU A  42
SER A  45
 None
 0.62A 1qzzA-3qljA:
6.9		 1qzzA-3qljA:
25.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_1
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 3qlj SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		3 / 3 HIS A  22
ASP A  37
ASN A  73
 None
 0.53A 1wg8B-3qljA:
8.4		 1wg8B-3qljA:
26.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B7Z_B_MK1B200_1
(HIV-1 PROTEASE)		 3qlj SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 12 GLY A 102
ALA A 101
ILE A 178
ALA A 130
VAL A  74
 CL  A 302 (-3.6A)
None
None
None
None
 0.98A 2b7zA-3qljA:
undetectable		 2b7zA-3qljA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B7Z_B_MK1B200_2
(HIV-1 PROTEASE)		 3qlj SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 12 GLY A 102
ALA A 101
ILE A 178
ALA A 130
VAL A  74
 CL  A 302 (-3.6A)
None
None
None
None
 0.92A 2b7zB-3qljA:
undetectable		 2b7zB-3qljA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMY_A_ROCA401_2
(PROTEASE)		 3qlj SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 12 LEU A  24
GLY A  15
ALA A  14
ILE A  10
ALA A  27
 None
 0.79A 2nmyB-3qljA:
undetectable		 2nmyB-3qljA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_1
(PROTEASE)		 3qlj SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 12 LEU A  24
GLY A  15
ALA A  14
ILE A  10
ALA A  27
 None
 0.80A 2nmzA-3qljA:
undetectable		 2nmzA-3qljA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_3
(PROTEASE)		 3qlj SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 12 LEU A  24
GLY A  15
ALA A  14
ILE A  10
ALA A  27
 None
 0.74A 2nmzB-3qljA:
undetectable		 2nmzB-3qljA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGQ_A_AB1A200_1
(FIV PROTEASE)		 3qlj SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 10 LEU A 238
ILE A  10
VAL A   9
GLY A  19
ILE A  18
 None
 1.02A 3ogqA-3qljA:
undetectable		 3ogqA-3qljA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUG_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3qlj SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 12 VAL A   8
GLY A  15
ALA A  14
THR A  12
ALA A 101
 None
 1.10A 3sugA-3qljA:
undetectable		 3sugA-3qljA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HXY_B_ACAB502_1
(PLM1)		 3qlj SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		4 / 7 VAL A 104
SER A 158
GLN A 168
TYR A 171
 CL  A 302 ( 4.8A)
None
None
None
 0.65A 4hxyB-3qljA:
17.2		 4hxyB-3qljA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3qlj SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 12 VAL A  33
VAL A   3
ALA A  14
LEU A 234
VAL A  96
 None
 1.23A 4ib4A-3qljA:
undetectable		 4ib4A-3qljA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3qlj SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 12 VAL A  33
VAL A   3
ALA A  14
LEU A 234
VAL A  96
 None
 1.23A 4nc3A-3qljA:
undetectable		 4nc3A-3qljA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 3qlj SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 12 VAL A 231
ILE A 199
ILE A  18
GLY A  17
VAL A  56
 None
 1.02A 4y8wC-3qljA:
undetectable		 4y8wC-3qljA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 3qlj SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 12 GLY A  13
GLY A  15
ARG A  20
ILE A  38
ASN A  73
 None
 1.14A 5fa8A-3qljA:
6.5		 5fa8A-3qljA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 3qlj SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		3 / 3 GLY A  15
ASP A  37
ASN A  73
 None
 0.51A 5jglA-3qljA:
6.7		 5jglA-3qljA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA602_0
(THIOCYANATE
DEHYDROGENASE)		 3qlj SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		3 / 3 LYS A 175
HIS A 128
HIS A 124
 None
None
CL  A 302 (-4.5A)
 1.03A 5oexA-3qljA:
undetectable		 5oexA-3qljA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB602_0
(THIOCYANATE
DEHYDROGENASE)		 3qlj SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		3 / 3 LYS A 175
HIS A 128
HIS A 124
 None
None
CL  A 302 (-4.5A)
 0.98A 5oexB-3qljA:
undetectable		 5oexB-3qljA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC603_0
(THIOCYANATE
DEHYDROGENASE)		 3qlj SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		3 / 3 LYS A 175
HIS A 128
HIS A 124
 None
None
CL  A 302 (-4.5A)
 0.97A 5oexC-3qljA:
undetectable		 5oexC-3qljA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD603_0
(THIOCYANATE
DEHYDROGENASE)		 3qlj SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		3 / 3 LYS A 175
HIS A 128
HIS A 124
 None
None
CL  A 302 (-4.5A)
 1.01A 5oexD-3qljA:
undetectable		 5oexD-3qljA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7P_A_SAMA501_0
(OXAC)		 3qlj SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 12 PHE A  91
GLU A  66
ALA A  31
GLY A  30
LEU A  94
 None
 0.81A 5w7pA-3qljA:
5.5		 5w7pA-3qljA:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WY0_A_SAMA800_0
(SMALL RNA
2'-O-METHYLTRANSFERA
SE)		 3qlj SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 12 GLY A  13
GLY A  15
ASP A  37
ILE A  38
ILE A  18
 None
 0.68A 5wy0A-3qljA:
5.2		 5wy0A-3qljA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7F_A_SAMA301_0
(PUTATIVE
O-METHYLTRANSFERASE
RV1220C)		 3qlj SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 12 GLY A  17
GLY A  13
GLY A  15
ILE A  38
ALA A 101
 None
 1.11A 5x7fA-3qljA:
7.9		 5x7fA-3qljA:
27.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AZ3_1_PAR11801_1
(RRNA ALPHA
RIBOSOMAL PROTEIN
EL18)		 3qlj SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		4 / 4 ARG A 152
ARG A   7
GLY A   6
ARG A  32
 None
 1.30A 6az3P-3qljA:
0.0		 6az3P-3qljA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		 3qlj SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 9 ALA A 160
ALA A 173
SER A 172
VAL A 120
GLY A 177
 None
 1.28A 6bklA-3qljA:
undetectable
6bklB-3qljA:
undetectable
6bklC-3qljA:
undetectable
6bklD-3qljA:
undetectable		 6bklA-3qljA:
6.43
6bklB-3qljA:
6.43
6bklC-3qljA:
6.43
6bklD-3qljA:
6.43