SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qll'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DF7_A_MTXA501_1
(DIHYDROFOLATE
REDUCTASE)		 3qll CITRATE LYASE
(Yersinia
pestis) 		5 / 12 ILE A  81
ALA A  79
LEU A  97
LEU A 111
ILE A  84
 None
 0.76A 1df7A-3qllA:
undetectable		 1df7A-3qllA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 3qll CITRATE LYASE
(Yersinia
pestis) 		4 / 8 THR A 102
GLY A 133
ILE A 140
VAL A 137
 None
 0.93A 1rxcB-3qllA:
undetectable		 1rxcB-3qllA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_E_URFE2031_1
(URIDINE
PHOSPHORYLASE)		 3qll CITRATE LYASE
(Yersinia
pestis) 		4 / 8 THR A 102
GLY A 133
ILE A 140
VAL A 137
 None
 0.95A 1rxcE-3qllA:
undetectable		 1rxcE-3qllA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_I_URFI2041_1
(URIDINE
PHOSPHORYLASE)		 3qll CITRATE LYASE
(Yersinia
pestis) 		4 / 8 THR A 102
GLY A 133
ILE A 140
VAL A 137
 None
 0.93A 1rxcI-3qllA:
undetectable		 1rxcI-3qllA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_K_URFK2061_1
(URIDINE
PHOSPHORYLASE)		 3qll CITRATE LYASE
(Yersinia
pestis) 		4 / 8 THR A 102
GLY A 133
ILE A 140
VAL A 137
 None
 0.94A 1rxcK-3qllA:
undetectable		 1rxcK-3qllA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CD2_A_FOLA307_0
(DIHYDROFOLATE
REDUCTASE)		 3qll CITRATE LYASE
(Yersinia
pestis) 		5 / 12 ILE A 225
ALA A 223
ILE A 220
THR A 206
ILE A 228
 None
 1.06A 2cd2A-3qllA:
undetectable		 2cd2A-3qllA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_G_ASDG1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3qll CITRATE LYASE
(Yersinia
pestis) 		4 / 7 PHE A 214
LEU A 134
LEU A 150
ALA A 188
 None
 1.02A 2vcvG-3qllA:
undetectable		 2vcvG-3qllA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE503_1
(PHOSPHOLIPASE A2)		 3qll CITRATE LYASE
(Yersinia
pestis) 		5 / 11 VAL A 131
LEU A 134
GLY A 133
ILE A 140
SER A 139
 None
 1.35A 3bjwE-3qllA:
undetectable		 3bjwE-3qllA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZV_B_ECNB411_1
(FLAVOHEMOGLOBIN)		 3qll CITRATE LYASE
(Yersinia
pestis) 		5 / 9 ILE A 140
ALA A 188
LEU A 150
LEU A 108
ALA A 105
 None
 1.10A 3ozvB-3qllA:
undetectable		 3ozvB-3qllA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S79_A_ASDA601_1
(CYTOCHROME P450 19A1)		 3qll CITRATE LYASE
(Yersinia
pestis) 		5 / 12 PHE A 152
ALA A 159
ASP A 160
LEU A 172
LEU A 134
 None
 1.27A 3s79A-3qllA:
undetectable		 3s79A-3qllA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3qll CITRATE LYASE
(Yersinia
pestis) 		4 / 4 PRO A  94
LEU A  87
ILE A  55
ARG A  51
 None
 1.38A 3w1wA-3qllA:
undetectable		 3w1wA-3qllA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_A_URFA1301_1
(URIDINE
PHOSPHORYLASE)		 3qll CITRATE LYASE
(Yersinia
pestis) 		4 / 8 THR A 102
GLY A 133
ILE A 140
VAL A 137
 None
 0.93A 4e1vA-3qllA:
undetectable		 4e1vA-3qllA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_C_URFC1301_1
(URIDINE
PHOSPHORYLASE)		 3qll CITRATE LYASE
(Yersinia
pestis) 		4 / 8 THR A 102
GLY A 133
ILE A 140
VAL A 137
 None
 0.90A 4e1vC-3qllA:
undetectable		 4e1vC-3qllA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_D_URFD1301_1
(URIDINE
PHOSPHORYLASE)		 3qll CITRATE LYASE
(Yersinia
pestis) 		4 / 8 THR A 102
GLY A 133
ILE A 140
VAL A 137
 None
 0.95A 4e1vD-3qllA:
undetectable		 4e1vD-3qllA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)		 3qll CITRATE LYASE
(Yersinia
pestis) 		4 / 8 THR A 102
GLY A 133
ILE A 140
VAL A 137
 None
 0.90A 4e1vE-3qllA:
undetectable		 4e1vE-3qllA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_G_URFG1301_1
(URIDINE
PHOSPHORYLASE)		 3qll CITRATE LYASE
(Yersinia
pestis) 		4 / 8 THR A 102
GLY A 133
ILE A 140
VAL A 137
 None
 0.89A 4e1vG-3qllA:
undetectable		 4e1vG-3qllA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_H_URFH1301_1
(URIDINE
PHOSPHORYLASE)		 3qll CITRATE LYASE
(Yersinia
pestis) 		4 / 8 THR A 102
GLY A 133
ILE A 140
VAL A 137
 None
 0.94A 4e1vH-3qllA:
undetectable		 4e1vH-3qllA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_A_TMQA202_1
(DIHYDROFOLATE
REDUCTASE)		 3qll CITRATE LYASE
(Yersinia
pestis) 		6 / 12 ILE A  81
ALA A  79
ASP A  37
LEU A  97
LEU A 111
ILE A  84
 None
 1.05A 4m2xA-3qllA:
undetectable		 4m2xA-3qllA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_C_TMQC202_1
(DIHYDROFOLATE
REDUCTASE)		 3qll CITRATE LYASE
(Yersinia
pestis) 		5 / 12 ILE A  81
ALA A  79
LEU A  97
LEU A 111
ILE A  84
 None
 0.76A 4m2xC-3qllA:
undetectable		 4m2xC-3qllA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_E_TMQE202_1
(DIHYDROFOLATE
REDUCTASE)		 3qll CITRATE LYASE
(Yersinia
pestis) 		6 / 12 ILE A  81
ALA A  79
ASP A  37
LEU A  97
LEU A 111
ILE A  84
 None
 1.03A 4m2xE-3qllA:
undetectable		 4m2xE-3qllA:
19.75