SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qlv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)		 3qlv GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 5
(Rattus
norvegicus) 		5 / 11 VAL A 207
LEU A 208
LEU A 225
THR A 226
THR A 227
 None
 1.29A 1dmyA-3qlvA:
undetectable		 1dmyA-3qlvA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3qlv GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 5
(Rattus
norvegicus) 		4 / 6 THR A 377
SER A 136
GLY A 370
ILE A 369
 None
 0.91A 1gtnD-3qlvA:
undetectable
1gtnE-3qlvA:
undetectable		 1gtnD-3qlvA:
9.82
1gtnE-3qlvA:
9.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_A_115A2_2
(HMG-COA REDUCTASE)		 3qlv GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 5
(Rattus
norvegicus) 		4 / 8 ASN A 272
LEU A  23
ALA A  26
LEU A  27
 None
 0.62A 1hwiB-3qlvA:
undetectable		 1hwiB-3qlvA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_A_115A2_2
(HMG-COA REDUCTASE)		 3qlv GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 5
(Rattus
norvegicus) 		4 / 8 GLU A 271
LEU A  23
ALA A  26
LEU A  27
 None
 1.01A 1hwiB-3qlvA:
undetectable		 1hwiB-3qlvA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_D_115D3_1
(HMG-COA REDUCTASE)		 3qlv GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 5
(Rattus
norvegicus) 		4 / 8 ASN A 272
LEU A  23
ALA A  26
LEU A  27
 None
 0.61A 1hwiC-3qlvA:
undetectable		 1hwiC-3qlvA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_D_115D3_1
(HMG-COA REDUCTASE)		 3qlv GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 5
(Rattus
norvegicus) 		4 / 8 GLU A 271
LEU A  23
ALA A  26
LEU A  27
 None
 0.99A 1hwiC-3qlvA:
undetectable		 1hwiC-3qlvA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_A_VIBA502_1
(THIAMIN
PYROPHOSPHOKINASE)		 3qlv GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 5
(Rattus
norvegicus) 		4 / 8 TRP A 372
SER A 131
SER A 127
THR A 226
 None
 1.02A 1ig3A-3qlvA:
3.1
1ig3B-3qlvA:
2.1		 1ig3A-3qlvA:
20.69
1ig3B-3qlvA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB504_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3qlv GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 5
(Rattus
norvegicus) 		4 / 7 LEU A 356
ILE A 358
ALA A 129
ILE A 196
 None
 0.92A 1oniB-3qlvA:
undetectable
1oniC-3qlvA:
undetectable		 1oniB-3qlvA:
17.78
1oniC-3qlvA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGP_A_PCFA1213_0
(WNT INHIBITORY
FACTOR 1)		 3qlv GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 5
(Rattus
norvegicus) 		6 / 12 LEU A 144
ILE A 197
LEU A 208
ILE A 196
VAL A 192
PRO A 140
 None
 1.38A 2ygpA-3qlvA:
undetectable		 2ygpA-3qlvA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM9_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3qlv GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 5
(Rattus
norvegicus) 		4 / 8 MET A 380
ALA A 379
GLY A 370
ILE A 369
 None
 0.59A 2zm9A-3qlvA:
undetectable		 2zm9A-3qlvA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_1
(UNCHARACTERIZED
PROTEIN PH0793)		 3qlv GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 5
(Rattus
norvegicus) 		3 / 3 MET A 380
GLU A 360
ASP A 241
 None
 1.12A 3a25A-3qlvA:
undetectable		 3a25A-3qlvA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3qlv GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 5
(Rattus
norvegicus) 		4 / 6 SER A 249
THR A 227
THR A 340
PHE A 251
 None
 1.10A 4acbC-3qlvA:
undetectable		 4acbC-3qlvA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_O_BEZO801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3qlv GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 5
(Rattus
norvegicus) 		4 / 6 PHE A  49
HIS A  98
MET A  63
LEU A  75
 None
 1.36A 5dzka-3qlvA:
undetectable
5dzko-3qlvA:
undetectable		 5dzka-3qlvA:
20.20
5dzko-3qlvA:
40.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_S_BEZS801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3qlv GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 5
(Rattus
norvegicus) 		4 / 6 PHE A  49
HIS A  98
MET A  63
LEU A  75
 None
 1.35A 5dzke-3qlvA:
undetectable
5dzks-3qlvA:
undetectable		 5dzke-3qlvA:
20.20
5dzks-3qlvA:
40.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KLA_A_ACTA1505_0
(MATERNAL PROTEIN
PUMILIO)		 3qlv GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 5
(Rattus
norvegicus) 		3 / 3 HIS A 366
LYS A 361
PHE A 230
 None
 1.38A 5klaA-3qlvA:
undetectable		 5klaA-3qlvA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A4I_B_TRPB403_0
(TRYPTOPHAN
2,3-DIOXYGENASE)		 3qlv GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 5
(Rattus
norvegicus) 		4 / 7 ARG A 154
GLU A 156
THR A 106
PRO A 107
 None
 1.38A 6a4iB-3qlvA:
undetectable		 6a4iB-3qlvA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_0
(SERUM ALBUMIN)		 3qlv GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 5
(Rattus
norvegicus) 		5 / 12 LEU A 208
ILE A 238
VAL A 126
LEU A 356
LEU A 233
 None
 1.15A 6a7pA-3qlvA:
undetectable		 6a7pA-3qlvA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_I_PCFI101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 3qlv GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 5
(Rattus
norvegicus) 		5 / 11 ASP A 125
SER A 122
TYR A 354
GLY A 338
ALA A  28
 None
 1.36A 6hu9A-3qlvA:
undetectable
6hu9E-3qlvA:
undetectable
6hu9I-3qlvA:
undetectable		 6hu9A-3qlvA:
22.52
6hu9E-3qlvA:
19.77
6hu9I-3qlvA:
9.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 3qlv GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 5
(Rattus
norvegicus) 		5 / 10 ASP A 125
SER A 122
TYR A 354
GLY A 338
ALA A  28
 None
 1.31A 6hu9L-3qlvA:
undetectable
6hu9P-3qlvA:
undetectable
6hu9T-3qlvA:
undetectable		 6hu9L-3qlvA:
22.52
6hu9P-3qlvA:
19.77
6hu9T-3qlvA:
9.92