SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qm1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_D_BRLD503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3qm1 CINNAMOYL ESTERASE
(Lactobacillus
johnsonii) 		5 / 12 GLY A  70
SER A  68
LEU A 163
HIS A  32
LEU A  13
 NA  A 276 (-3.4A)
None
None
None
None
 1.41A 1fm6D-3qm1A:
undetectable		 1fm6D-3qm1A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3qm1 CINNAMOYL ESTERASE
(Lactobacillus
johnsonii) 		4 / 7 GLY A 104
HIS A 105
THR A 239
ILE A  30
 None
ZYC  A 245 ( 4.4A)
None
None
 0.95A 1gtnF-3qm1A:
undetectable
1gtnG-3qm1A:
undetectable		 1gtnF-3qm1A:
14.06
1gtnG-3qm1A:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE9_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 3qm1 CINNAMOYL ESTERASE
(Lactobacillus
johnsonii) 		5 / 12 LEU A 191
SER A 113
VAL A 200
HIS A 225
HIS A 105
 None
CL  A 292 (-4.9A)
None
ZYC  A 245 ( 3.9A)
ZYC  A 245 ( 4.4A)
 1.35A 1ie9A-3qm1A:
undetectable		 1ie9A-3qm1A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_1
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 3qm1 CINNAMOYL ESTERASE
(Lactobacillus
johnsonii) 		3 / 3 THR A   3
GLU A  18
ASP A  52
 None
 0.83A 1nt2A-3qm1A:
4.2		 1nt2A-3qm1A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S8F_B_BEZB1503_0
(RAS-RELATED PROTEIN
RAB-9A)		 3qm1 CINNAMOYL ESTERASE
(Lactobacillus
johnsonii) 		4 / 6 VAL A 147
THR A 144
LEU A 158
PHE A 160
 NA  A 287 ( 4.0A)
ZYC  A 245 (-3.8A)
None
None
 0.99A 1s8fB-3qm1A:
4.8		 1s8fB-3qm1A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		 3qm1 CINNAMOYL ESTERASE
(Lactobacillus
johnsonii) 		3 / 3 LEU A   6
LEU A  13
SER A  68
 None
 0.53A 1tlmA-3qm1A:
undetectable		 1tlmA-3qm1A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1300_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 3qm1 CINNAMOYL ESTERASE
(Lactobacillus
johnsonii) 		5 / 11 GLY A  33
ALA A 106
VAL A 199
VAL A 200
HIS A 225
 ZYC  A 245 (-3.4A)
ZYC  A 245 (-3.0A)
NA  A 249 ( 4.0A)
None
ZYC  A 245 ( 3.9A)
 0.39A 1ukbA-3qm1A:
21.9		 1ukbA-3qm1A:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3qm1 CINNAMOYL ESTERASE
(Lactobacillus
johnsonii) 		5 / 12 GLY A  70
SER A  68
LEU A 163
HIS A  32
LEU A  13
 NA  A 276 (-3.4A)
None
None
None
None
 1.46A 1zgyA-3qm1A:
undetectable		 1zgyA-3qm1A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5P_A_TACA7101_1
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 3qm1 CINNAMOYL ESTERASE
(Lactobacillus
johnsonii) 		5 / 12 VAL A  91
TYR A 119
ILE A  55
TYR A 101
ILE A 123
 None
 1.30A 3q5pA-3qm1A:
undetectable		 3q5pA-3qm1A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_2
(ANDROGEN RECEPTOR)		 3qm1 CINNAMOYL ESTERASE
(Lactobacillus
johnsonii) 		4 / 7 ASN A  89
LEU A 102
LEU A 118
ILE A 100
 None
 1.05A 4okwA-3qm1A:
undetectable		 4okwA-3qm1A:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESL_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3qm1 CINNAMOYL ESTERASE
(Lactobacillus
johnsonii) 		4 / 5 ALA A 116
PRO A 131
GLY A 222
LEU A 217
 CL  A 292 ( 3.7A)
None
NA  A 280 (-4.0A)
NA  A 281 ( 4.3A)
 1.00A 5eslA-3qm1A:
undetectable		 5eslA-3qm1A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA502_2
(CYTOCHROME P450 2C9)		 3qm1 CINNAMOYL ESTERASE
(Lactobacillus
johnsonii) 		3 / 3 LEU A   6
VAL A  91
ASP A  94
 None
 0.64A 5x23A-3qm1A:
undetectable		 5x23A-3qm1A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CB4_A_BEZA502_0
(CANAVALIN)		 3qm1 CINNAMOYL ESTERASE
(Lactobacillus
johnsonii) 		4 / 4 GLY A  22
LYS A  -5
GLN A  -1
ASN A  54
 NA  A 248 ( 3.8A)
CL  A 306 (-4.2A)
None
None
 1.50A 6cb4A-3qm1A:
0.3		 6cb4A-3qm1A:
19.96