SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qm2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3qm2 PHOSPHOSERINE
AMINOTRANSFERASE
(Salmonella
enterica) 		5 / 10 ALA A  12
ALA A 196
LEU A 180
VAL A 262
ILE A 179
 None
 1.34A 1claA-3qm2A:
undetectable		 1claA-3qm2A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S14_B_NOVB2300_1
(TOPOISOMERASE IV
SUBUNIT B)		 3qm2 PHOSPHOSERINE
AMINOTRANSFERASE
(Salmonella
enterica) 		5 / 12 ASN A 142
SER A 140
ASP A 141
ASP A  95
ASP A 213
 None
 1.43A 1s14B-3qm2A:
undetectable		 1s14B-3qm2A:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_0
(VP39)		 3qm2 PHOSPHOSERINE
AMINOTRANSFERASE
(Salmonella
enterica) 		5 / 12 GLY A 201
PRO A  11
GLY A  10
VAL A  18
ALA A 245
 None
 0.98A 1vptA-3qm2A:
undetectable		 1vptA-3qm2A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_A_ACTA2001_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 3qm2 PHOSPHOSERINE
AMINOTRANSFERASE
(Salmonella
enterica) 		4 / 5 TYR A 339
SER A 337
THR A 153
ASN A 151
 None
 1.37A 1yvpA-3qm2A:
3.6		 1yvpA-3qm2A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_A_ACTA544_0
(ACETYLCHOLINESTERASE)		 3qm2 PHOSPHOSERINE
AMINOTRANSFERASE
(Salmonella
enterica) 		4 / 8 GLY A 261
GLY A 260
ALA A 263
ALA A 264
 None
 0.59A 2ha4A-3qm2A:
undetectable		 2ha4A-3qm2A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_B_ACTB601_0
(ACETYLCHOLINESTERASE)		 3qm2 PHOSPHOSERINE
AMINOTRANSFERASE
(Salmonella
enterica) 		4 / 7 GLY A 261
GLY A 260
ALA A 263
ALA A 264
 None
 0.62A 2ha4B-3qm2A:
undetectable		 2ha4B-3qm2A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z9W_A_PXLA1197_1
(ASPARTATE
AMINOTRANSFERASE)		 3qm2 PHOSPHOSERINE
AMINOTRANSFERASE
(Salmonella
enterica) 		5 / 11 CYH A 149
THR A 153
ASP A 174
SER A 177
LYS A 198
 None
 0.69A 2z9wA-3qm2A:
32.5		 2z9wA-3qm2A:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z9W_B_PXLB1197_1
(ASPARTATE
AMINOTRANSFERASE)		 3qm2 PHOSPHOSERINE
AMINOTRANSFERASE
(Salmonella
enterica) 		5 / 11 CYH A 149
THR A 153
ASP A 174
SER A 177
LYS A 198
 None
 0.68A 2z9wB-3qm2A:
32.4		 2z9wB-3qm2A:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 3qm2 PHOSPHOSERINE
AMINOTRANSFERASE
(Salmonella
enterica) 		4 / 8 ILE A 159
ASN A 151
SER A 177
LYS A 198
 None
 1.09A 2zw9B-3qm2A:
undetectable		 2zw9B-3qm2A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_A_SVRA508_2
(PHOSPHOLIPASE A2)		 3qm2 PHOSPHOSERINE
AMINOTRANSFERASE
(Salmonella
enterica) 		5 / 9 VAL A 331
GLY A 327
LYS A 326
THR A 153
GLY A 156
 None
 1.12A 3bjwG-3qm2A:
undetectable		 3bjwG-3qm2A:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA502_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 3qm2 PHOSPHOSERINE
AMINOTRANSFERASE
(Salmonella
enterica) 		4 / 8 TYR A 148
LEU A 139
VAL A 169
VAL A 171
 None
 0.95A 4em2A-3qm2A:
undetectable		 4em2A-3qm2A:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		 3qm2 PHOSPHOSERINE
AMINOTRANSFERASE
(Salmonella
enterica) 		4 / 7 PRO A 163
VAL A 171
ALA A 173
PHE A 175
 None
 0.84A 4lb2A-3qm2A:
undetectable		 4lb2A-3qm2A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8Y_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3qm2 PHOSPHOSERINE
AMINOTRANSFERASE
(Salmonella
enterica) 		5 / 12 GLU A 345
ILE A 338
ALA A 336
PHE A 302
VAL A 300
 None
 1.07A 4u8yB-3qm2A:
undetectable		 4u8yB-3qm2A:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_C_NOVC2000_1
(DNA GYRASE SUBUNIT B)		 3qm2 PHOSPHOSERINE
AMINOTRANSFERASE
(Salmonella
enterica) 		5 / 12 ASN A 299
ARG A 129
ASP A  98
ALA A 103
SER A 177
 None
 1.08A 4uroC-3qm2A:
undetectable		 4uroC-3qm2A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_B_BEZB306_0
(BETA-LACTAMASE VIM-2)		 3qm2 PHOSPHOSERINE
AMINOTRANSFERASE
(Salmonella
enterica) 		3 / 3 HIS A 266
ASN A 269
ALA A 273
 None
 0.34A 5n4tB-3qm2A:
undetectable		 5n4tB-3qm2A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSP_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3qm2 PHOSPHOSERINE
AMINOTRANSFERASE
(Salmonella
enterica) 		4 / 7 VAL A 125
ILE A 123
PRO A 133
ALA A 130
 None
 0.64A 5ospA-3qm2A:
undetectable		 5ospA-3qm2A:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 3qm2 PHOSPHOSERINE
AMINOTRANSFERASE
(Salmonella
enterica) 		4 / 6 LEU A 350
PHE A   5
PHE A   7
LEU A 325
 None
 1.19A 5x19P-3qm2A:
undetectable		 5x19P-3qm2A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_1
(CYTOCHROME P450 1A1)		 3qm2 PHOSPHOSERINE
AMINOTRANSFERASE
(Salmonella
enterica) 		5 / 7 ASN A 199
GLY A 250
ALA A  53
VAL A  69
LEU A 207
 None
 1.26A 6dwnB-3qm2A:
undetectable		 6dwnB-3qm2A:
11.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_0
(STIE PROTEIN)		 3qm2 PHOSPHOSERINE
AMINOTRANSFERASE
(Salmonella
enterica) 		6 / 12 LEU A 205
GLY A  76
ILE A 179
VAL A 208
LEU A 207
ILE A 209
 None
 1.47A 6ecxA-3qm2A:
2.1		 6ecxA-3qm2A:
21.77