SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qm3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_B_ZMRB466_2
(NEURAMINIDASE)		 3qm3 FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Campylobacter
jejuni) 		3 / 3 ASP A 286
ARG A 340
ILE A 343
 None
 0.87A 1a4gB-3qm3A:
undetectable		 1a4gB-3qm3A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_B_DESB128_1
(TRANSTHYRETIN)		 3qm3 FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Campylobacter
jejuni) 		5 / 11 LEU A 138
LEU A 140
LEU A 204
LEU A 149
THR A 151
 None
 1.28A 1tz8A-3qm3A:
undetectable
1tz8B-3qm3A:
undetectable		 1tz8A-3qm3A:
16.71
1tz8B-3qm3A:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		 3qm3 FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Campylobacter
jejuni) 		4 / 8 HIS A 105
GLU A 169
HIS A 221
ALA A 214
 ZN  A 355 (-3.2A)
ZN  A 355 (-1.9A)
ZN  A 355 (-3.2A)
None
 1.01A 2bnnA-3qm3A:
undetectable
2bnnB-3qm3A:
undetectable		 2bnnA-3qm3A:
18.11
2bnnB-3qm3A:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_A_VIAA901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3qm3 FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Campylobacter
jejuni) 		5 / 11 HIS A 221
ASN A 219
ILE A 168
LEU A 236
ILE A 279
 ZN  A 355 (-3.2A)
None
None
None
None
 1.25A 2h42A-3qm3A:
undetectable		 2h42A-3qm3A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EBZ_B_017B201_1
(PROTEASE)		 3qm3 FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Campylobacter
jejuni) 		5 / 11 LEU A 138
ILE A 213
GLY A 205
ILE A 207
ILE A 168
 None
 1.08A 3ebzA-3qm3A:
undetectable		 3ebzA-3qm3A:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_B_ERYB195_1
(REPRESSOR PROTEIN
MPHR(A))		 3qm3 FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Campylobacter
jejuni) 		4 / 7 ASN A 256
ASN A 282
HIS A 260
ALA A 214
 None
None
ZN  A 355 (-3.2A)
None
 1.44A 3frqB-3qm3A:
undetectable		 3frqB-3qm3A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECLA600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3qm3 FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Campylobacter
jejuni) 		4 / 8 LEU A 132
GLY A  10
ALA A  92
ILE A  42
 None
FMT  A 356 (-3.6A)
None
None
 0.83A 3jusA-3qm3A:
undetectable		 3jusA-3qm3A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3qm3 FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Campylobacter
jejuni) 		4 / 8 LEU A 132
GLY A  10
ALA A  92
ILE A  42
 None
FMT  A 356 (-3.6A)
None
None
 0.83A 3jusA-3qm3A:
undetectable		 3jusA-3qm3A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_A_GJZA506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3qm3 FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Campylobacter
jejuni) 		4 / 6 LEU A 236
ILE A 213
ALA A 214
THR A 192
 None
 0.82A 3mdrA-3qm3A:
undetectable		 3mdrA-3qm3A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R2C_A_ACTA153_0
(N UTILIZATION
SUBSTANCE PROTEIN B)		 3qm3 FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Campylobacter
jejuni) 		4 / 4 ASN A  75
GLY A  76
GLU A  77
LYS A  66
 None
 1.45A 3r2cA-3qm3A:
0.0		 3r2cA-3qm3A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3qm3 FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Campylobacter
jejuni) 		5 / 12 LEU A 159
LEU A 166
LEU A 204
ILE A 118
ARG A 108
 None
 1.24A 4f4dA-3qm3A:
undetectable		 4f4dA-3qm3A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 3qm3 FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Campylobacter
jejuni) 		4 / 7 TYR A  68
ILE A  42
ASP A 284
PHE A  60
 None
 0.80A 4iqqA-3qm3A:
undetectable		 4iqqA-3qm3A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J14_A_X2NA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 3qm3 FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Campylobacter
jejuni) 		5 / 10 LEU A 236
PHE A 257
ILE A 213
ALA A 214
THR A 192
 None
 1.11A 4j14A-3qm3A:
undetectable		 4j14A-3qm3A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAH_A_LNRA600_1
(PHENYLALANINE
HYDROXYLASE)		 3qm3 FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Campylobacter
jejuni) 		4 / 6 LEU A 166
HIS A 105
HIS A 260
GLU A 169
 None
ZN  A 355 (-3.2A)
ZN  A 355 (-3.2A)
ZN  A 355 (-1.9A)
 1.02A 4pahA-3qm3A:
undetectable		 4pahA-3qm3A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAH_A_LNRA600_1
(PHENYLALANINE
HYDROXYLASE)		 3qm3 FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Campylobacter
jejuni) 		4 / 6 LEU A 236
HIS A 260
HIS A 221
GLU A 169
 None
ZN  A 355 (-3.2A)
ZN  A 355 (-3.2A)
ZN  A 355 (-1.9A)
 0.98A 4pahA-3qm3A:
undetectable		 4pahA-3qm3A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UY8_7_TRP71002_0
(TRYPTOPHANASE)		 3qm3 FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Campylobacter
jejuni) 		4 / 4 ILE A 118
ASN A 121
ILE A  82
VAL A  78
 None
 1.03A 4uy87-3qm3A:
undetectable		 4uy87-3qm3A:
4.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZ8_A_GCSA208_1
(GLUCANASE/CHITOSANAS
E)		 3qm3 FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Campylobacter
jejuni) 		4 / 7 ARG A 331
TYR A  95
GLU A 334
ASP A  40
 None
 1.12A 4zz8A-3qm3A:
undetectable		 4zz8A-3qm3A:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_A_FOLA201_0
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 3qm3 FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Campylobacter
jejuni) 		5 / 12 GLY A 222
ASN A  62
THR A 103
ASN A  35
VAL A  37
 None
 1.14A 5d0yA-3qm3A:
undetectable		 5d0yA-3qm3A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_C_ACTC1740_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGS
FAD-BINDING SUBUNIT)		 3qm3 FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Campylobacter
jejuni) 		4 / 4 VAL A  78
GLU A  77
GLY A 116
LEU A 117
 None
 0.94A 5g5gC-3qm3A:
undetectable		 5g5gC-3qm3A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3qm3 FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Campylobacter
jejuni) 		5 / 12 HIS A 102
VAL A  11
ALA A  33
GLY A  84
ALA A  85
 None
FMT  A 356 (-4.2A)
None
None
None
 1.10A 5kirB-3qm3A:
undetectable		 5kirB-3qm3A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6PAH_A_DAHA600_1
(PHENYLALANINE
4-MONOOXYGENASE)		 3qm3 FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Campylobacter
jejuni) 		4 / 6 LEU A 166
HIS A 105
HIS A 260
GLU A 169
 None
ZN  A 355 (-3.2A)
ZN  A 355 (-3.2A)
ZN  A 355 (-1.9A)
 1.00A 6pahA-3qm3A:
undetectable		 6pahA-3qm3A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6PAH_A_DAHA600_1
(PHENYLALANINE
4-MONOOXYGENASE)		 3qm3 FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Campylobacter
jejuni) 		4 / 6 LEU A 236
HIS A 260
HIS A 221
GLU A 169
 None
ZN  A 355 (-3.2A)
ZN  A 355 (-3.2A)
ZN  A 355 (-1.9A)
 1.06A 6pahA-3qm3A:
undetectable		 6pahA-3qm3A:
22.34