SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qmj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHU_A_ESTA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 3qmj ENOYL-COA HYDRATASE,
ECHA8_6
(Mycobacterium
marinum) 		5 / 12 GLY A 109
ASN A 102
LEU A  51
ILE A 108
LEU A  90
 None
 1.33A 1lhuA-3qmjA:
undetectable		 1lhuA-3qmjA:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_G_SAMG199_0
(METHIONINE REPRESSOR)		 3qmj ENOYL-COA HYDRATASE,
ECHA8_6
(Mycobacterium
marinum) 		5 / 10 ALA A  34
LEU A  38
ALA A  89
PHE A  93
GLY A  92
 None
 1.22A 1mjqG-3qmjA:
undetectable
1mjqH-3qmjA:
undetectable		 1mjqG-3qmjA:
19.14
1mjqH-3qmjA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VE3_A_REAA1445_1
(PUTATIVE CYTOCHROME
P450 120)		 3qmj ENOYL-COA HYDRATASE,
ECHA8_6
(Mycobacterium
marinum) 		5 / 12 ALA A 110
LEU A 127
ALA A 170
VAL A 150
GLY A 151
 None
 1.08A 2ve3A-3qmjA:
undetectable		 2ve3A-3qmjA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_B_ADNB601_1
(METHIONYL-TRNA
SYNTHETASE)		 3qmj ENOYL-COA HYDRATASE,
ECHA8_6
(Mycobacterium
marinum) 		5 / 12 ALA A 100
GLY A  57
GLY A 109
ILE A 112
LEU A  22
 None
 0.82A 2x1lB-3qmjA:
undetectable		 2x1lB-3qmjA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_A_PFLA319_1
(GLR4197 PROTEIN)		 3qmj ENOYL-COA HYDRATASE,
ECHA8_6
(Mycobacterium
marinum) 		4 / 7 ILE A  87
LEU A  86
THR A 111
ILE A 112
 None
 0.97A 3p50A-3qmjA:
undetectable		 3p50A-3qmjA:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_B_PFLB319_1
(GLR4197 PROTEIN)		 3qmj ENOYL-COA HYDRATASE,
ECHA8_6
(Mycobacterium
marinum) 		4 / 7 ILE A  87
LEU A  86
THR A 111
ILE A 112
 None
 0.97A 3p50B-3qmjA:
undetectable		 3p50B-3qmjA:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_C_PFLC319_1
(GLR4197 PROTEIN)		 3qmj ENOYL-COA HYDRATASE,
ECHA8_6
(Mycobacterium
marinum) 		4 / 7 ILE A  87
LEU A  86
THR A 111
ILE A 112
 None
 0.97A 3p50C-3qmjA:
undetectable		 3p50C-3qmjA:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_D_PFLD320_1
(GLR4197 PROTEIN)		 3qmj ENOYL-COA HYDRATASE,
ECHA8_6
(Mycobacterium
marinum) 		4 / 7 ILE A  87
LEU A  86
THR A 111
ILE A 112
 None
 0.98A 3p50D-3qmjA:
undetectable		 3p50D-3qmjA:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_E_PFLE319_1
(GLR4197 PROTEIN)		 3qmj ENOYL-COA HYDRATASE,
ECHA8_6
(Mycobacterium
marinum) 		4 / 7 ILE A  87
LEU A  86
THR A 111
ILE A 112
 None
 0.97A 3p50E-3qmjA:
undetectable		 3p50E-3qmjA:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_A_RTZA2_1
(CYTOCHROME P450 2D6)		 3qmj ENOYL-COA HYDRATASE,
ECHA8_6
(Mycobacterium
marinum) 		5 / 11 LEU A  14
THR A  13
VAL A  49
SER A  59
LEU A  90
 None
 1.37A 3tbgA-3qmjA:
undetectable		 3tbgA-3qmjA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB4_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 3qmj ENOYL-COA HYDRATASE,
ECHA8_6
(Mycobacterium
marinum) 		5 / 10 LEU A 104
GLY A 103
PHE A  58
ASN A 102
LYS A 128
 FMT  A 252 ( 4.6A)
None
None
None
None
 1.43A 4eb4D-3qmjA:
undetectable		 4eb4D-3qmjA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 3qmj ENOYL-COA HYDRATASE,
ECHA8_6
(Mycobacterium
marinum) 		4 / 7 ILE A 112
LEU A 127
GLY A 105
PHE A  58
 None
 0.92A 4iqqA-3qmjA:
undetectable		 4iqqA-3qmjA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KM2_B_TOPB202_1
(DIHYDROFOLATE
REDUCTASE)		 3qmj ENOYL-COA HYDRATASE,
ECHA8_6
(Mycobacterium
marinum) 		5 / 12 ILE A 108
LEU A  97
VAL A  49
LEU A  51
ILE A 112
 None
 0.97A 4km2B-3qmjA:
undetectable		 4km2B-3qmjA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_J_4LEJ401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3qmj ENOYL-COA HYDRATASE,
ECHA8_6
(Mycobacterium
marinum) 		6 / 9 LEU A  51
LEU A  14
ALA A  36
LEU A   3
ALA A  32
LEU A  29
 None
 1.23A 4z91F-3qmjA:
undetectable
4z91G-3qmjA:
undetectable
4z91H-3qmjA:
undetectable
4z91I-3qmjA:
undetectable
4z91J-3qmjA:
undetectable		 4z91F-3qmjA:
20.55
4z91G-3qmjA:
20.55
4z91H-3qmjA:
20.55
4z91I-3qmjA:
20.55
4z91J-3qmjA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_1
(CDL2.3B)		 3qmj ENOYL-COA HYDRATASE,
ECHA8_6
(Mycobacterium
marinum) 		5 / 12 LEU A 175
LEU A  90
LEU A  97
PHE A  58
LEU A  16
 None
 1.15A 5iepA-3qmjA:
undetectable		 5iepA-3qmjA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JI0_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3qmj ENOYL-COA HYDRATASE,
ECHA8_6
(Mycobacterium
marinum) 		5 / 11 ILE A 112
LEU A 145
LEU A  90
ALA A  91
VAL A 101
 None
 1.15A 5ji0A-3qmjA:
undetectable		 5ji0A-3qmjA:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR0_A_478A101_2
(PROTEASE E35D-APV)		 3qmj ENOYL-COA HYDRATASE,
ECHA8_6
(Mycobacterium
marinum) 		5 / 9 LEU A 185
ASN A 102
GLY A  53
GLY A 109
ILE A 112
 None
 1.02A 5kr0B-3qmjA:
undetectable		 5kr0B-3qmjA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 3qmj ENOYL-COA HYDRATASE,
ECHA8_6
(Mycobacterium
marinum) 		4 / 7 ILE A 112
LEU A 127
GLY A 105
PHE A  58
 None
 0.88A 5nooA-3qmjA:
undetectable		 5nooA-3qmjA:
20.43