SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qmq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NT2_A_SAMA301_1 (FIBRILLARIN-LIKE PRE-RRNA PROCESSING PROTEIN)	3qmq	AUTOINDUCER-2 (AI-2) MODIFYING PROTEIN LSRG (Escherichia coli)	3 / 3	THR A 73 GLU A 17 ASP A 13	None	0.86A	1nt2A-3qmqA: undetectable	1nt2A-3qmqA: 19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1W76_B_GNTB1538_1 (ACETYLCHOLINESTERASE)	3qmq	AUTOINDUCER-2 (AI-2) MODIFYING PROTEIN LSRG (Escherichia coli)	5 / 10	GLY A 28 GLU A 32 SER A 29 PHE A 22 HIS A 65	None	1.11A	1w76B-3qmqA: undetectable	1w76B-3qmqA: 12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AP6_A_TLFA300_0 (PROBABLE STRIGOLACTONE ESTERASE DAD2)	3qmq	AUTOINDUCER-2 (AI-2) MODIFYING PROTEIN LSRG (Escherichia coli)	5 / 12	PHE A 38 ILE A 52 VAL A 6 VAL A 21 PHE A 22	None	1.21A	6ap6A-3qmqA: undetectable	6ap6A-3qmqA: 17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AP6_B_TLFB300_0 (PROBABLE STRIGOLACTONE ESTERASE DAD2)	3qmq	AUTOINDUCER-2 (AI-2) MODIFYING PROTEIN LSRG (Escherichia coli)	5 / 12	PHE A 38 ILE A 52 VAL A 6 VAL A 21 PHE A 22	None	1.21A	6ap6B-3qmqA: undetectable	6ap6B-3qmqA: 17.06

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1NT2_A_SAMA301_1","FIBRILLARIN-LIKE PRE-RRNA PROCESSING PROTEIN","3qmq","AUTOINDUCER-2 (AI-2) MODIFYING PROTEIN LSRG","Escherichia coli",3,"THR A  73;GLU A  17;ASP A  13","None","0.86A","1nt2A-3qmqA:undetectable","1nt2A-3qmqA:19.80"],["1W76_B_GNTB1538_1","ACETYLCHOLINESTERASE","3qmq","AUTOINDUCER-2 (AI-2) MODIFYING PROTEIN LSRG","Escherichia coli",5,"GLY A  28;GLU A  32;SER A  29;PHE A  22;HIS A  65","None","1.11A","1w76B-3qmqA:undetectable","1w76B-3qmqA:12.31"],["6AP6_A_TLFA300_0","PROBABLE STRIGOLACTONE ESTERASE DAD2","3qmq","AUTOINDUCER-2 (AI-2) MODIFYING PROTEIN LSRG","Escherichia coli",5,"PHE A  38;ILE A  52;VAL A   6;VAL A  21;PHE A  22","None","1.21A","6ap6A-3qmqA:undetectable","6ap6A-3qmqA:17.06"],["6AP6_B_TLFB300_0","PROBABLE STRIGOLACTONE ESTERASE DAD2","3qmq","AUTOINDUCER-2 (AI-2) MODIFYING PROTEIN LSRG","Escherichia coli",5,"PHE A  38;ILE A  52;VAL A   6;VAL A  21;PHE A  22","None","1.21A","6ap6B-3qmqA:undetectable","6ap6B-3qmqA:17.06"]]