SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qn3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_E_BEZE509_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3qn3 ENOLASE
(Campylobacter
jejuni) 		4 / 7 TYR A 396
ILE A 166
PRO A 168
ALA A 177
 None
 1.16A 1oniD-3qn3A:
undetectable
1oniE-3qn3A:
undetectable		 1oniD-3qn3A:
16.15
1oniE-3qn3A:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_G_BEZG513_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3qn3 ENOLASE
(Campylobacter
jejuni) 		4 / 5 PHE A 171
ARG A 233
ILE A 166
PRO A 168
 None
 1.46A 1oniG-3qn3A:
0.8
1oniH-3qn3A:
undetectable		 1oniG-3qn3A:
16.15
1oniH-3qn3A:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 3qn3 ENOLASE
(Campylobacter
jejuni) 		5 / 12 ILE A 166
ALA A 388
GLY A 206
LEU A 220
LEU A 188
 None
 0.97A 1rjdA-3qn3A:
undetectable		 1rjdA-3qn3A:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 3qn3 ENOLASE
(Campylobacter
jejuni) 		5 / 12 ILE A 166
ALA A 388
GLY A 206
LEU A 220
LEU A 188
 None
 1.01A 1rjdB-3qn3A:
undetectable		 1rjdB-3qn3A:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 3qn3 ENOLASE
(Campylobacter
jejuni) 		5 / 12 ILE A 166
ALA A 388
GLY A 206
LEU A 220
LEU A 188
 None
 0.99A 1rjdC-3qn3A:
undetectable		 1rjdC-3qn3A:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN)		 3qn3 ENOLASE
(Campylobacter
jejuni) 		5 / 11 ILE A  78
THR A  92
LEU A  81
VAL A  25
THR A 117
 None
 1.09A 1tw4A-3qn3A:
undetectable		 1tw4A-3qn3A:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W0G_A_MYTA1499_1
(CYTOCHROME P450 3A4)		 3qn3 ENOLASE
(Campylobacter
jejuni) 		4 / 6 SER A 114
ILE A 339
THR A 312
ALA A  48
 None
 0.97A 1w0gA-3qn3A:
undetectable		 1w0gA-3qn3A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 3qn3 ENOLASE
(Campylobacter
jejuni) 		6 / 12 VAL A  70
ILE A  78
THR A  92
LEU A  81
VAL A  25
THR A 117
 None
 1.34A 2jn3A-3qn3A:
undetectable		 2jn3A-3qn3A:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA507_0
(CHORISMATE SYNTHASE)		 3qn3 ENOLASE
(Campylobacter
jejuni) 		3 / 3 LEU A 270
ASN A 214
ARG A 266
 None
 0.76A 2qhfA-3qn3A:
undetectable		 2qhfA-3qn3A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_A_J01A500_1
(ORF12)		 3qn3 ENOLASE
(Campylobacter
jejuni) 		4 / 8 VAL A  70
LEU A  27
GLY A  33
ALA A 120
 None
 0.93A 2xfsA-3qn3A:
undetectable		 2xfsA-3qn3A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_A_J01A1436_1
(ORF12)		 3qn3 ENOLASE
(Campylobacter
jejuni) 		4 / 8 VAL A  70
LEU A  27
GLY A  33
ALA A 120
 None
 0.95A 2xh9A-3qn3A:
undetectable		 2xh9A-3qn3A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 3qn3 ENOLASE
(Campylobacter
jejuni) 		5 / 12 ILE A 316
VAL A 311
ILE A 336
ILE A 331
LEU A 348
 None
 1.22A 3fpjB-3qn3A:
undetectable		 3fpjB-3qn3A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_A_BEZA264_0
(ECHA1_1)		 3qn3 ENOLASE
(Campylobacter
jejuni) 		4 / 8 ILE A 339
LEU A 133
ALA A 121
ALA A 122
 None
 0.54A 3r9tA-3qn3A:
undetectable		 3r9tA-3qn3A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_B_BEZB264_0
(ECHA1_1)		 3qn3 ENOLASE
(Campylobacter
jejuni) 		4 / 7 ILE A 339
LEU A 133
ALA A 121
ALA A 122
 None
 0.57A 3r9tB-3qn3A:
undetectable		 3r9tB-3qn3A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_B_RKEB401_1
(PROTON-GATED ION
CHANNEL)		 3qn3 ENOLASE
(Campylobacter
jejuni) 		4 / 8 ASN A 214
ASP A 160
VAL A 240
LEU A 270
 None
 0.99A 4f8hB-3qn3A:
undetectable
4f8hC-3qn3A:
undetectable		 4f8hB-3qn3A:
21.04
4f8hC-3qn3A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_D_RKED401_1
(PROTON-GATED ION
CHANNEL)		 3qn3 ENOLASE
(Campylobacter
jejuni) 		4 / 8 ASN A 214
ASP A 160
VAL A 240
LEU A 270
 None
 1.00A 4f8hD-3qn3A:
undetectable
4f8hE-3qn3A:
undetectable		 4f8hD-3qn3A:
21.04
4f8hE-3qn3A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_E_RKEE401_1
(PROTON-GATED ION
CHANNEL)		 3qn3 ENOLASE
(Campylobacter
jejuni) 		4 / 8 VAL A 240
LEU A 270
ASN A 214
ASP A 160
 None
 0.99A 4f8hA-3qn3A:
undetectable
4f8hE-3qn3A:
undetectable		 4f8hA-3qn3A:
21.04
4f8hE-3qn3A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMC_A_29JA604_1
(TRANSPORTER)		 3qn3 ENOLASE
(Campylobacter
jejuni) 		4 / 7 ILE A 339
PHE A 369
LEU A 133
THR A 379
 None
 0.97A 4mmcA-3qn3A:
undetectable		 4mmcA-3qn3A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 3qn3 ENOLASE
(Campylobacter
jejuni) 		5 / 12 PHE A 369
ALA A 118
THR A 312
THR A 342
LEU A 111
 None
 1.21A 4qzuA-3qn3A:
undetectable		 4qzuA-3qn3A:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RJD_B_TFPB204_1
(CALMODULIN)		 3qn3 ENOLASE
(Campylobacter
jejuni) 		4 / 8 GLY A 385
GLU A 204
GLU A 280
ALA A 237
 None
None
MG  A 601 (-3.0A)
None
 0.84A 4rjdA-3qn3A:
undetectable
4rjdB-3qn3A:
undetectable		 4rjdA-3qn3A:
10.33
4rjdB-3qn3A:
10.33