SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qnk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NB9_A_RBFA401_1
(HYPOTHETICAL PROTEIN
FLJ11149)		 3qnk PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		5 / 9 ILE A  55
VAL A  57
GLU A 145
LEU A 211
ILE A 412
 None
 1.32A 1nb9A-3qnkA:
undetectable		 1nb9A-3qnkA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA501_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3qnk PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		4 / 7 PHE A 471
ALA A 416
ILE A 251
GLU A 261
 None
 1.12A 1oniA-3qnkA:
undetectable
1oniB-3qnkA:
undetectable		 1oniA-3qnkA:
14.86
1oniB-3qnkA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI517_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3qnk PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		4 / 7 ILE A 251
GLU A 261
PHE A 471
ALA A 416
 None
 1.02A 1oniG-3qnkA:
undetectable
1oniI-3qnkA:
undetectable		 1oniG-3qnkA:
14.86
1oniI-3qnkA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_B_ADNB1246_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3qnk PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		4 / 8 GLY A 206
VAL A 232
GLU A 231
ILE A 263
 None
 0.92A 1pk7B-3qnkA:
undetectable		 1pk7B-3qnkA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 3qnk PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		3 / 3 ASP A  58
THR A 522
PRO A 523
 None
 0.72A 2pynB-3qnkA:
undetectable		 2pynB-3qnkA:
11.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 3qnk PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		3 / 3 ASP A  58
THR A 522
PRO A 523
 None
 0.71A 2qakB-3qnkA:
undetectable		 2qakB-3qnkA:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKK_E_MFXE1100_1
(TOPOISOMERASE IV
DNA)		 3qnk PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		3 / 3 ARG A 367
GLU A 303
SER A 352
 None
 0.86A 2xkkA-3qnkA:
undetectable
2xkkC-3qnkA:
2.0		 2xkkA-3qnkA:
21.92
2xkkC-3qnkA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX95_0
(PROTEIN S100-B)		 3qnk PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		3 / 3 CYH A 111
PHE A 114
PHE A 115
 None
 0.39A 3cr5X-3qnkA:
undetectable		 3cr5X-3qnkA:
12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3qnk PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		4 / 5 PRO A 245
THR A 364
VAL A 365
GLY A 351
 None
 1.15A 3elzA-3qnkA:
undetectable		 3elzA-3qnkA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_B_H3PB552_1
(GLUTAMATE
DEHYDROGENASE)		 3qnk PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		3 / 3 TYR A 319
TYR A 383
ILE A 305
 None
 0.79A 3eteA-3qnkA:
undetectable
3eteB-3qnkA:
undetectable		 3eteA-3qnkA:
23.54
3eteB-3qnkA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)		 3qnk PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		4 / 8 PRO A 169
SER A 171
LEU A 156
ASP A 157
 None
 1.09A 3lsfH-3qnkA:
undetectable		 3lsfH-3qnkA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)		 3qnk PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		4 / 8 TYR A 105
PRO A 169
SER A 171
LEU A 156
 None
 1.08A 3lsfH-3qnkA:
undetectable		 3lsfH-3qnkA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)		 3qnk PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		4 / 8 TYR A 143
PRO A 169
LEU A 156
ASP A 157
 None
 0.92A 3lsfH-3qnkA:
undetectable		 3lsfH-3qnkA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5R_A_KANA2002_1
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 3qnk PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		5 / 11 ASN A  69
ILE A 251
TYR A 248
GLU A 470
ILE A 469
 None
 1.49A 3q5rA-3qnkA:
undetectable		 3q5rA-3qnkA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5S_A_ACHA1289_0
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 3qnk PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		4 / 6 VAL A 446
TYR A 248
GLU A 466
ILE A 469
 None
 1.16A 3q5sA-3qnkA:
undetectable		 3q5sA-3qnkA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UAY_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3qnk PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		5 / 10 THR A 188
GLY A 206
VAL A 232
GLU A 231
ILE A 263
 None
 1.04A 3uayA-3qnkA:
undetectable		 3uayA-3qnkA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1005_1
(HEMOLYTIC LECTIN
CEL-III)		 3qnk PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		3 / 3 ASP A 371
GLY A 296
TYR A 285
 None
 0.70A 3w9tC-3qnkA:
undetectable		 3w9tC-3qnkA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG503_1
(HEMOLYTIC LECTIN
CEL-III)		 3qnk PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		3 / 3 ASP A 371
GLY A 296
TYR A 285
 None
 0.69A 3w9tG-3qnkA:
undetectable		 3w9tG-3qnkA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ2_A_FK5A200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 3qnk PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		5 / 11 TYR A 396
VAL A 363
ILE A 354
ILE A 389
MET A 370
 None
 1.31A 4dz2A-3qnkA:
undetectable
4dz2B-3qnkA:
undetectable		 4dz2A-3qnkA:
15.20
4dz2B-3qnkA:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ2_B_FK5B200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 3qnk PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		5 / 11 MET A 370
TYR A 396
VAL A 363
ILE A 354
ILE A 389
 None
 1.31A 4dz2A-3qnkA:
undetectable
4dz2B-3qnkA:
undetectable		 4dz2A-3qnkA:
15.20
4dz2B-3qnkA:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR3_A_GLYA701_0
(GLYCINE--TRNA LIGASE)		 3qnk PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		4 / 6 GLU A 466
GLU A 309
ARG A 342
GLU A 340
 None
 1.25A 4kr3A-3qnkA:
undetectable		 4kr3A-3qnkA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 3qnk PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		4 / 5 THR A 332
GLY A 334
HIS A 350
ASP A 329
 None
 1.19A 5c0oH-3qnkA:
undetectable		 5c0oH-3qnkA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_B_C2FB402_1
(THYMIDYLATE SYNTHASE)		 3qnk PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		3 / 3 ASN A 256
ASP A 241
GLY A 242
 None
 0.63A 5fctB-3qnkA:
undetectable		 5fctB-3qnkA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB603_1
(PHIAB6 TAILSPIKE)		 3qnk PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		3 / 3 VAL A 439
GLU A 340
GLU A 309
 None
 0.82A 5jsdB-3qnkA:
undetectable
5jsdC-3qnkA:
undetectable		 5jsdB-3qnkA:
21.95
5jsdC-3qnkA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3qnk PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		4 / 6 VAL A 507
LEU A 304
ILE A 469
PHE A 308
 None
 0.88A 5jw1A-3qnkA:
undetectable		 5jw1A-3qnkA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3qnk PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		4 / 6 VAL A 108
VAL A 153
ARG A 531
ILE A 529
 None
 1.04A 5jw1B-3qnkA:
undetectable		 5jw1B-3qnkA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_A_SAMA301_0
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 3qnk PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		5 / 12 THR A 522
GLU A 173
GLY A 152
TYR A 150
ILE A 154
 None
 1.05A 5kvaA-3qnkA:
undetectable		 5kvaA-3qnkA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_B_SAMB301_0
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 3qnk PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		5 / 12 THR A 522
GLU A 173
GLY A 152
TYR A 150
ILE A 154
 None
 1.05A 5kvaB-3qnkA:
undetectable		 5kvaB-3qnkA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ONL_A_010A302_0
(YNDL)		 3qnk PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		4 / 5 GLU A 417
GLU A 470
GLU A 474
PHE A 471
 None
 1.32A 5onlA-3qnkA:
undetectable		 5onlA-3qnkA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HRJ_A_010A302_0
(YNDL)		 3qnk PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		4 / 5 GLU A 417
GLU A 470
GLU A 474
PHE A 471
 None
 1.31A 6hrjA-3qnkA:
undetectable		 6hrjA-3qnkA:
18.34