SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qnt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_A_FUAA702_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3qnt NIEMANN-PICK C1-LIKE
PROTEIN 1
(Homo
sapiens) 		5 / 12 TYR A 156
PHE A  35
SER A  53
LEU A 103
ALA A 158
 None
 1.05A 1q23A-3qntA:
undetectable
1q23B-3qntA:
undetectable		 1q23A-3qntA:
20.42
1q23B-3qntA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_B_SAMB500_0
(HYPOTHETICAL PROTEIN)		 3qnt NIEMANN-PICK C1-LIKE
PROTEIN 1
(Homo
sapiens) 		4 / 6 ASP A 118
VAL A 121
PRO A 114
THR A 111
 None
 1.44A 2q6oB-3qntA:
undetectable		 2q6oB-3qntA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_B_CLMB221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3qnt NIEMANN-PICK C1-LIKE
PROTEIN 1
(Homo
sapiens) 		5 / 12 SER A  56
PHE A  35
SER A  53
LEU A 103
VAL A 121
 None
 1.42A 3u9fB-3qntA:
undetectable
3u9fC-3qntA:
undetectable		 3u9fB-3qntA:
20.42
3u9fC-3qntA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_B_CLMB221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3qnt NIEMANN-PICK C1-LIKE
PROTEIN 1
(Homo
sapiens) 		5 / 12 TYR A 156
PHE A  35
SER A  53
LEU A 103
VAL A 121
 None
 1.18A 3u9fB-3qntA:
undetectable
3u9fC-3qntA:
undetectable		 3u9fB-3qntA:
20.42
3u9fC-3qntA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_H_CLMH221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3qnt NIEMANN-PICK C1-LIKE
PROTEIN 1
(Homo
sapiens) 		5 / 12 TYR A 156
PHE A  35
SER A  53
LEU A 103
VAL A 121
 None
 1.22A 3u9fH-3qntA:
undetectable
3u9fI-3qntA:
undetectable		 3u9fH-3qntA:
20.42
3u9fI-3qntA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_R_CLMR221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3qnt NIEMANN-PICK C1-LIKE
PROTEIN 1
(Homo
sapiens) 		5 / 10 TYR A 156
PHE A  35
SER A  53
LEU A 103
VAL A 121
 None
 1.23A 3u9fR-3qntA:
undetectable		 3u9fR-3qntA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ4_B_ACTB403_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 3qnt NIEMANN-PICK C1-LIKE
PROTEIN 1
(Homo
sapiens) 		3 / 3 ARG A 174
ASP A 258
ARG A 176
 None
 0.54A 4wq4B-3qntA:
undetectable		 4wq4B-3qntA:
23.91