SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qo0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_A_DVAA6_0
(GRAMICIDIN B)		 3qo0 FAB FRAGMENT OF
IMMUNOGLOBULIN G1
HEAVY CHAIN
(Homo
sapiens) 		3 / 3 ALA B  64
VAL B  48
TRP B  47
 None
 0.93A 1jo3A-3qo0B:
undetectable		 1jo3A-3qo0B:
4.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_B_DVAB6_0
(GRAMICIDIN B)		 3qo0 FAB FRAGMENT OF
IMMUNOGLOBULIN G1
HEAVY CHAIN
(Homo
sapiens) 		3 / 3 ALA B  64
VAL B  48
TRP B  47
 None
 0.93A 1jo3B-3qo0B:
undetectable		 1jo3B-3qo0B:
4.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_K_URFK2061_1
(URIDINE
PHOSPHORYLASE)		 3qo0 FAB FRAGMENT OF
IMMUNOGLOBULIN G1
HEAVY CHAIN
(Homo
sapiens) 		4 / 8 THR B 116
GLY B  10
MET B  95
PRO B 208
 None
 0.92A 1rxcK-3qo0B:
undetectable		 1rxcK-3qo0B:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_A_SALA301_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 3qo0 FAB FRAGMENT OF
IMMUNOGLOBULIN G1
HEAVY CHAIN
(Homo
sapiens) 		4 / 6 ARG B  74
ILE B  72
VAL B  34
HIS B  35
 None
 1.25A 3deuA-3qo0B:
undetectable		 3deuA-3qo0B:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_B_SALB302_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 3qo0 FAB FRAGMENT OF
IMMUNOGLOBULIN G1
HEAVY CHAIN
(Homo
sapiens) 		4 / 5 ARG B  74
ILE B  72
VAL B  34
HIS B  35
 None
 1.30A 3deuB-3qo0B:
undetectable		 3deuB-3qo0B:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG305_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3qo0 FAB FRAGMENT OF
IMMUNOGLOBULIN G1
HEAVY CHAIN
(Homo
sapiens) 		3 / 3 ASP B  91
ARG B  69
LYS B  89
 None
 0.99A 3wipG-3qo0B:
undetectable		 3wipG-3qo0B:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_A_URFA1301_1
(URIDINE
PHOSPHORYLASE)		 3qo0 FAB FRAGMENT OF
IMMUNOGLOBULIN G1
HEAVY CHAIN
(Homo
sapiens) 		4 / 8 THR B 116
GLY B  10
MET B  95
PRO B 208
 None
 0.92A 4e1vA-3qo0B:
undetectable		 4e1vA-3qo0B:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_C_URFC1301_1
(URIDINE
PHOSPHORYLASE)		 3qo0 FAB FRAGMENT OF
IMMUNOGLOBULIN G1
HEAVY CHAIN
(Homo
sapiens) 		4 / 8 THR B 116
GLY B  10
MET B  95
PRO B 208
 None
 0.91A 4e1vC-3qo0B:
undetectable		 4e1vC-3qo0B:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_D_URFD1301_1
(URIDINE
PHOSPHORYLASE)		 3qo0 FAB FRAGMENT OF
IMMUNOGLOBULIN G1
HEAVY CHAIN
(Homo
sapiens) 		4 / 8 THR B 116
GLY B  10
MET B  95
PRO B 208
 None
 0.91A 4e1vD-3qo0B:
undetectable		 4e1vD-3qo0B:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)		 3qo0 FAB FRAGMENT OF
IMMUNOGLOBULIN G1
HEAVY CHAIN
(Homo
sapiens) 		4 / 8 THR B 116
GLY B  10
MET B  95
PRO B 208
 None
 0.96A 4e1vE-3qo0B:
undetectable		 4e1vE-3qo0B:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3qo0 FAB FRAGMENT OF
IMMUNOGLOBULIN G1
HEAVY CHAIN
(Homo
sapiens) 		5 / 11 SER B 194
GLY B 140
THR B 141
ALA B 142
THR B 137
 None
 0.90A 4qvnH-3qo0B:
undetectable
4qvnI-3qo0B:
undetectable		 4qvnH-3qo0B:
20.90
4qvnI-3qo0B:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3qo0 FAB FRAGMENT OF
IMMUNOGLOBULIN G1
HEAVY CHAIN
(Homo
sapiens) 		5 / 10 SER B 194
GLY B 140
THR B 141
ALA B 142
THR B 137
 None
 0.90A 4qvnV-3qo0B:
undetectable
4qvnW-3qo0B:
undetectable		 4qvnV-3qo0B:
20.90
4qvnW-3qo0B:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3qo0 FAB FRAGMENT OF
IMMUNOGLOBULIN G1
HEAVY CHAIN
(Homo
sapiens) 		5 / 12 SER B 194
GLY B 140
THR B 141
ALA B 142
THR B 137
 None
 0.88A 4qvpH-3qo0B:
undetectable
4qvpI-3qo0B:
undetectable		 4qvpH-3qo0B:
20.90
4qvpI-3qo0B:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3qo0 FAB FRAGMENT OF
IMMUNOGLOBULIN G1
HEAVY CHAIN
(Homo
sapiens) 		5 / 12 SER B 194
GLY B 140
THR B 141
ALA B 142
THR B 137
 None
 0.88A 4qvpV-3qo0B:
undetectable
4qvpW-3qo0B:
undetectable		 4qvpV-3qo0B:
20.90
4qvpW-3qo0B:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3qo0 FAB FRAGMENT OF
IMMUNOGLOBULIN G1
HEAVY CHAIN
(Homo
sapiens) 		5 / 11 SER B 194
GLY B 140
THR B 141
ALA B 142
THR B 137
 None
 0.90A 4qvqH-3qo0B:
undetectable
4qvqI-3qo0B:
undetectable		 4qvqH-3qo0B:
20.90
4qvqI-3qo0B:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3qo0 FAB FRAGMENT OF
IMMUNOGLOBULIN G1
HEAVY CHAIN
(Homo
sapiens) 		5 / 11 SER B 194
GLY B 140
THR B 141
ALA B 142
THR B 137
 None
 0.89A 4qvqV-3qo0B:
undetectable
4qvqW-3qo0B:
undetectable		 4qvqV-3qo0B:
20.90
4qvqW-3qo0B:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 3qo0 FAB FRAGMENT OF
IMMUNOGLOBULIN G1
HEAVY CHAIN
(Homo
sapiens) 		5 / 11 SER B 194
GLY B 140
THR B 141
ALA B 142
THR B 137
 None
 0.93A 4qvvH-3qo0B:
undetectable		 4qvvH-3qo0B:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 3qo0 FAB FRAGMENT OF
IMMUNOGLOBULIN G1
HEAVY CHAIN
(Homo
sapiens) 		5 / 11 SER B 194
GLY B 140
THR B 141
ALA B 142
THR B 137
 None
 0.92A 4qvvV-3qo0B:
undetectable		 4qvvV-3qo0B:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 3qo0 FAB FRAGMENT OF
IMMUNOGLOBULIN G1
HEAVY CHAIN
(Homo
sapiens) 		5 / 11 SER B 194
GLY B 140
THR B 141
ALA B 142
THR B 137
 None
 0.92A 4qvyH-3qo0B:
undetectable		 4qvyH-3qo0B:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3qo0 FAB FRAGMENT OF
IMMUNOGLOBULIN G1
HEAVY CHAIN
(Homo
sapiens) 		5 / 12 SER B 194
GLY B 140
THR B 141
ALA B 142
THR B 137
 None
 0.92A 4qvyV-3qo0B:
undetectable
4qvyW-3qo0B:
undetectable		 4qvyV-3qo0B:
20.90
4qvyW-3qo0B:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3qo0 FAB FRAGMENT OF
IMMUNOGLOBULIN G1
HEAVY CHAIN
(Homo
sapiens) 		5 / 11 SER B 194
GLY B 140
THR B 141
ALA B 142
THR B 137
 None
 0.91A 4qw0H-3qo0B:
undetectable
4qw0I-3qo0B:
undetectable		 4qw0H-3qo0B:
20.90
4qw0I-3qo0B:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3qo0 FAB FRAGMENT OF
IMMUNOGLOBULIN G1
HEAVY CHAIN
(Homo
sapiens) 		5 / 11 SER B 194
GLY B 140
THR B 141
ALA B 142
THR B 137
 None
 0.91A 4qw0V-3qo0B:
undetectable
4qw0W-3qo0B:
undetectable		 4qw0V-3qo0B:
20.90
4qw0W-3qo0B:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3qo0 FAB FRAGMENT OF
IMMUNOGLOBULIN G1
HEAVY CHAIN
(Homo
sapiens) 		5 / 12 SER B 194
GLY B 140
THR B 141
ALA B 142
THR B 137
 None
 0.93A 4qw1H-3qo0B:
undetectable
4qw1I-3qo0B:
undetectable		 4qw1H-3qo0B:
20.90
4qw1I-3qo0B:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3qo0 FAB FRAGMENT OF
IMMUNOGLOBULIN G1
HEAVY CHAIN
(Homo
sapiens) 		5 / 12 SER B 194
GLY B 140
THR B 141
ALA B 142
THR B 137
 None
 0.93A 4qw1V-3qo0B:
undetectable
4qw1W-3qo0B:
undetectable		 4qw1V-3qo0B:
20.90
4qw1W-3qo0B:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3qo0 FAB FRAGMENT OF
IMMUNOGLOBULIN G1
HEAVY CHAIN
(Homo
sapiens) 		5 / 11 SER B 194
GLY B 140
THR B 141
ALA B 142
THR B 137
 None
 0.89A 5bxnH-3qo0B:
undetectable
5bxnI-3qo0B:
undetectable		 5bxnH-3qo0B:
20.90
5bxnI-3qo0B:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3qo0 FAB FRAGMENT OF
IMMUNOGLOBULIN G1
HEAVY CHAIN
(Homo
sapiens) 		5 / 12 SER B 194
GLY B 140
THR B 141
ALA B 142
THR B 137
 None
 0.91A 5cz7V-3qo0B:
undetectable
5cz7W-3qo0B:
undetectable		 5cz7V-3qo0B:
20.90
5cz7W-3qo0B:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 3qo0 FAB FRAGMENT OF
IMMUNOGLOBULIN G1
HEAVY CHAIN
(Homo
sapiens) 		5 / 11 SER B 194
GLY B 140
THR B 141
ALA B 142
THR B 137
 None
 0.90A 5d0xV-3qo0B:
undetectable		 5d0xV-3qo0B:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3qo0 FAB FRAGMENT OF
IMMUNOGLOBULIN G1
HEAVY CHAIN
(Homo
sapiens) 		5 / 12 SER B 194
GLY B 140
THR B 141
ALA B 142
THR B 137
 None
 0.87A 5l5fH-3qo0B:
undetectable
5l5fI-3qo0B:
undetectable		 5l5fH-3qo0B:
20.90
5l5fI-3qo0B:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3qo0 FAB FRAGMENT OF
IMMUNOGLOBULIN G1
HEAVY CHAIN
(Homo
sapiens) 		5 / 12 SER B 194
GLY B 140
THR B 141
ALA B 142
THR B 137
 None
 0.87A 5l5fV-3qo0B:
undetectable
5l5fW-3qo0B:
undetectable		 5l5fV-3qo0B:
20.90
5l5fW-3qo0B:
22.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MTH_A_ACTA302_0
(ANTIBODY FAB HEAVY
CHAIN)		 3qo0 FAB FRAGMENT OF
IMMUNOGLOBULIN G1
HEAVY CHAIN
(Homo
sapiens) 		4 / 5 SER B 118
ALA B 120
PHE B 152
LEU B 176
 None
 0.31A 5mthA-3qo0B:
25.6		 5mthA-3qo0B:
53.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_H_BO2H301_0
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3qo0 FAB FRAGMENT OF
IMMUNOGLOBULIN G1
HEAVY CHAIN
(Homo
sapiens) 		5 / 12 SER B 194
GLY B 140
THR B 141
ALA B 142
THR B 137
 None
 0.99A 6hwdH-3qo0B:
undetectable
6hwdI-3qo0B:
undetectable		 6hwdH-3qo0B:
17.95
6hwdI-3qo0B:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_V_BO2V301_0
(PROTEASOME SUBUNIT
BETA TYPE-2)		 3qo0 FAB FRAGMENT OF
IMMUNOGLOBULIN G1
HEAVY CHAIN
(Homo
sapiens) 		5 / 11 SER B 194
GLY B 140
THR B 141
ALA B 142
THR B 137
 None
 0.99A 6hwdV-3qo0B:
undetectable		 6hwdV-3qo0B:
17.95