SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qo6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4003_1
(SERUM ALBUMIN)		 3qo6 PROTEASE DO-LIKE 1,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 9 ILE A 277
VAL A 233
GLY A 249
ALA A 235
LEU A 286
 None
 1.19A 1e7bA-3qo6A:
undetectable		 1e7bA-3qo6A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3qo6 PROTEASE DO-LIKE 1,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 THR A 374
LEU A 420
ILE A 388
VAL A 396
ALA A 342
 None
 1.26A 2g72B-3qo6A:
undetectable		 2g72B-3qo6A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Y_A_ROCA201_2
(HIV-1 PROTEASE)		 3qo6 PROTEASE DO-LIKE 1,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 9 ILE A 236
GLY A 284
ILE A 296
VAL A 221
ILE A 219
 None
 1.16A 3d1yB-3qo6A:
undetectable		 3d1yB-3qo6A:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		 3qo6 PROTEASE DO-LIKE 1,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 HIS A 173
ASP A 203
GLY A 280
SER A 282
ALA A 299
 None
 0.80A 3keeA-3qo6A:
14.5		 3keeA-3qo6A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		 3qo6 PROTEASE DO-LIKE 1,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 HIS A 173
ASP A 203
GLY A 280
SER A 282
ALA A 299
 None
 0.76A 3keeB-3qo6A:
14.9		 3keeB-3qo6A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		 3qo6 PROTEASE DO-LIKE 1,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 HIS A 173
ASP A 203
GLY A 280
SER A 282
ALA A 299
 None
 0.77A 3keeC-3qo6A:
13.6		 3keeC-3qo6A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		 3qo6 PROTEASE DO-LIKE 1,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 HIS A 173
ASP A 203
GLY A 280
SER A 282
ALA A 299
 None
 0.78A 3keeD-3qo6A:
14.6		 3keeD-3qo6A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3qo6 PROTEASE DO-LIKE 1,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 TYR A 172
HIS A 173
ASP A 203
GLY A 280
ALA A 299
 None
 0.42A 3sudB-3qo6A:
12.9		 3sudB-3qo6A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3qo6 PROTEASE DO-LIKE 1,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 HIS A 173
ASP A 203
GLY A 280
SER A 282
ALA A 299
 None
 0.79A 3sueA-3qo6A:
8.8		 3sueA-3qo6A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3qo6 PROTEASE DO-LIKE 1,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 HIS A 173
ASP A 203
GLY A 280
SER A 282
ALA A 299
 None
 0.80A 3sueC-3qo6A:
12.6		 3sueC-3qo6A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3qo6 PROTEASE DO-LIKE 1,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 HIS A 173
ASP A 203
GLY A 280
SER A 282
ALA A 299
 None
 0.78A 3sueD-3qo6A:
8.8		 3sueD-3qo6A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3qo6 PROTEASE DO-LIKE 1,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		6 / 11 TYR A 172
HIS A 173
ASP A 203
GLY A 280
SER A 282
ALA A 299
 None
 0.76A 3sufC-3qo6A:
9.8		 3sufC-3qo6A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TZF_B_08DB280_1
(7,8-DIHYDROPTEROATE
SYNTHASE)		 3qo6 PROTEASE DO-LIKE 1,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 8 THR A 333
ARG A 334
PRO A 335
GLY A 412
 None
 1.03A 3tzfB-3qo6A:
undetectable		 3tzfB-3qo6A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		 3qo6 PROTEASE DO-LIKE 1,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 8 GLU A 414
GLU A 418
ASN A 392
GLY A 393
 None
 0.92A 4f93B-3qo6A:
undetectable		 4f93B-3qo6A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		 3qo6 PROTEASE DO-LIKE 1,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 8 GLU A 414
GLU A 418
ASN A 392
SER A 390
 None
 0.95A 4f93B-3qo6A:
undetectable		 4f93B-3qo6A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_B_CQAB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3qo6 PROTEASE DO-LIKE 1,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 8 GLY A 280
GLY A 284
VAL A 133
TYR A 134
 None
 0.66A 4fgzB-3qo6A:
undetectable		 4fgzB-3qo6A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_1
(PROTEASE)		 3qo6 PROTEASE DO-LIKE 1,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 GLY A 237
ILE A 300
ILE A 296
THR A 273
VAL A 169
 None
 1.04A 4q5mA-3qo6A:
undetectable		 4q5mA-3qo6A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 3qo6 PROTEASE DO-LIKE 1,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 THR A 245
THR A 247
ALA A 235
ALA A 275
ASN A 297
 None
 1.45A 4u15A-3qo6A:
undetectable		 4u15A-3qo6A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ALB_L_TIQL1210_2
(MEDI2452 LIGHT CHAIN)		 3qo6 PROTEASE DO-LIKE 1,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 8 SER A 156
TYR A 134
GLY A 157
ALA A 306
 None
 0.84A 5albL-3qo6A:
undetectable		 5albL-3qo6A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3qo6 PROTEASE DO-LIKE 1,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		3 / 3 SER A 260
ALA A 261
THR A 298
 None
 0.75A 5n0xB-3qo6A:
undetectable		 5n0xB-3qo6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0I_A_TRPA402_0
(TRYPTOPHAN--TRNA
LIGASE)		 3qo6 PROTEASE DO-LIKE 1,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 9 GLY A 283
VAL A 174
HIS A 173
ASP A 203
ILE A 314
 None
 1.42A 5v0iA-3qo6A:
undetectable		 5v0iA-3qo6A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0I_B_TRPB402_0
(TRYPTOPHAN--TRNA
LIGASE)		 3qo6 PROTEASE DO-LIKE 1,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 9 GLY A 283
VAL A 174
HIS A 173
ASP A 203
ILE A 314
 None
 1.39A 5v0iB-3qo6A:
undetectable		 5v0iB-3qo6A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_0
(NS3 PROTEASE)		 3qo6 PROTEASE DO-LIKE 1,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 HIS A 173
ASP A 203
GLY A 280
SER A 282
ALA A 299
 None
 0.74A 6c2mC-3qo6A:
12.9		 6c2mC-3qo6A:
11.49