SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qom'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E3V_A_DXCA801_0
(STEROID
DELTA-ISOMERASE)		 3qom 6-PHOSPHO-BETA-GLUCO
SIDASE
(Lactobacillus
plantarum) 		5 / 12 PHE A 287
VAL A 273
LEU A 304
MET A 211
ALA A 215
 None
 1.45A 1e3vA-3qomA:
undetectable		 1e3vA-3qomA:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3qom 6-PHOSPHO-BETA-GLUCO
SIDASE
(Lactobacillus
plantarum) 		5 / 10 GLY A  26
HIS A  64
THR A  95
SER A  35
ALA A  37
 None
PO4  A 482 (-3.7A)
None
None
None
 1.48A 1gtnO-3qomA:
undetectable
1gtnP-3qomA:
undetectable		 1gtnO-3qomA:
11.23
1gtnP-3qomA:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3qom 6-PHOSPHO-BETA-GLUCO
SIDASE
(Lactobacillus
plantarum) 		5 / 9 GLY A 229
ALA A 224
THR A 177
SER A 222
ALA A 223
 None
 1.50A 1gtnQ-3qomA:
undetectable
1gtnR-3qomA:
undetectable		 1gtnQ-3qomA:
11.23
1gtnR-3qomA:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KI3_B_PE2B2_1
(THYMIDINE KINASE)		 3qom 6-PHOSPHO-BETA-GLUCO
SIDASE
(Lactobacillus
plantarum) 		5 / 12 HIS A 402
ILE A 406
ILE A 373
MET A 360
TYR A 316
 None
 1.24A 1ki3B-3qomA:
0.7		 1ki3B-3qomA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_A_DVAA6_0
(GRAMICIDIN A)		 3qom 6-PHOSPHO-BETA-GLUCO
SIDASE
(Lactobacillus
plantarum) 		3 / 3 ALA A 475
VAL A 469
TRP A  14
 None
 0.88A 1nt5A-3qomA:
undetectable		 1nt5A-3qomA:
3.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_B_DVAB6_0
(GRAMICIDIN A)		 3qom 6-PHOSPHO-BETA-GLUCO
SIDASE
(Lactobacillus
plantarum) 		3 / 3 ALA A 475
VAL A 469
TRP A  14
 None
 0.88A 1nt5B-3qomA:
undetectable		 1nt5B-3qomA:
3.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_1
(DNA TOPOISOMERASE II)		 3qom 6-PHOSPHO-BETA-GLUCO
SIDASE
(Lactobacillus
plantarum) 		4 / 7 HIS A 216
TYR A 279
TYR A 269
LEU A 283
 None
 1.14A 1qzrA-3qomA:
undetectable		 1qzrA-3qomA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)		 3qom 6-PHOSPHO-BETA-GLUCO
SIDASE
(Lactobacillus
plantarum) 		4 / 7 TYR A 398
HIS A 402
LEU A 356
TYR A 317
 None
None
None
BGC  A 479 ( 4.8A)
 1.18A 1tuvA-3qomA:
undetectable		 1tuvA-3qomA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_L_TRPL81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3qom 6-PHOSPHO-BETA-GLUCO
SIDASE
(Lactobacillus
plantarum) 		6 / 12 GLY A 229
ALA A 224
THR A 177
GLY A 239
SER A 222
ALA A 223
 None
 1.46A 1utdL-3qomA:
undetectable
1utdM-3qomA:
undetectable		 1utdL-3qomA:
11.23
1utdM-3qomA:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_O_TRPO81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3qom 6-PHOSPHO-BETA-GLUCO
SIDASE
(Lactobacillus
plantarum) 		6 / 12 GLY A 229
ALA A 224
THR A 177
GLY A 239
SER A 222
ALA A 223
 None
 1.45A 1utdO-3qomA:
undetectable
1utdP-3qomA:
undetectable		 1utdO-3qomA:
11.23
1utdP-3qomA:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3qom 6-PHOSPHO-BETA-GLUCO
SIDASE
(Lactobacillus
plantarum) 		6 / 11 GLY A 229
ALA A 224
THR A 177
GLY A 239
SER A 222
ALA A 223
 None
 1.45A 1utdP-3qomA:
undetectable
1utdQ-3qomA:
undetectable		 1utdP-3qomA:
11.23
1utdQ-3qomA:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_C_DVAC6_0
(GRAMICIDIN D)		 3qom 6-PHOSPHO-BETA-GLUCO
SIDASE
(Lactobacillus
plantarum) 		3 / 3 ALA A 475
VAL A 469
TRP A  14
 None
 0.87A 1w5uC-3qomA:
undetectable
1w5uD-3qomA:
undetectable		 1w5uC-3qomA:
3.12
1w5uD-3qomA:
3.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3qom 6-PHOSPHO-BETA-GLUCO
SIDASE
(Lactobacillus
plantarum) 		4 / 7 GLY A 377
GLY A 419
PHE A 466
PHE A 442
 None
 0.92A 2qwxA-3qomA:
undetectable
2qwxB-3qomA:
undetectable		 2qwxA-3qomA:
18.79
2qwxB-3qomA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_B_NBVB1504_1
(GLUCOSYLCERAMIDASE)		 3qom 6-PHOSPHO-BETA-GLUCO
SIDASE
(Lactobacillus
plantarum) 		5 / 11 ASN A 179
GLU A 180
TYR A 317
GLU A 375
TRP A 423
 None
BGC  A 479 (-2.9A)
BGC  A 479 ( 4.8A)
None
None
 0.87A 2v3dB-3qomA:
15.3		 2v3dB-3qomA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_C_ACTC1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 3qom 6-PHOSPHO-BETA-GLUCO
SIDASE
(Lactobacillus
plantarum) 		3 / 3 PRO A 246
GLY A 355
TYR A 248
 None
 0.71A 2vouC-3qomA:
undetectable		 2vouC-3qomA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZI9_A_CL9A401_2
(DEOXYCYTIDINE KINASE)		 3qom 6-PHOSPHO-BETA-GLUCO
SIDASE
(Lactobacillus
plantarum) 		3 / 3 ASP A 115
PHE A 118
LEU A 122
 None
 0.46A 2zi9A-3qomA:
undetectable		 2zi9A-3qomA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_1
(N,N-DIMETHYLTRANSFER
ASE)		 3qom 6-PHOSPHO-BETA-GLUCO
SIDASE
(Lactobacillus
plantarum) 		3 / 3 TYR A 168
GLU A  24
ASP A  68
 None
 0.86A 3bxoA-3qomA:
undetectable		 3bxoA-3qomA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_B_SAMB238_1
(N,N-DIMETHYLTRANSFER
ASE)		 3qom 6-PHOSPHO-BETA-GLUCO
SIDASE
(Lactobacillus
plantarum) 		3 / 3 TYR A 168
GLU A  24
ASP A  68
 None
 0.83A 3bxoB-3qomA:
undetectable		 3bxoB-3qomA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX95_0
(PROTEIN S100-B)		 3qom 6-PHOSPHO-BETA-GLUCO
SIDASE
(Lactobacillus
plantarum) 		3 / 3 CYH A  87
PHE A  88
PHE A  85
 None
 1.04A 3cr5X-3qomA:
undetectable		 3cr5X-3qomA:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAL_B_1GNB999_1
(GALECTIN-7)		 3qom 6-PHOSPHO-BETA-GLUCO
SIDASE
(Lactobacillus
plantarum) 		4 / 6 ASN A 182
ARG A 267
ASN A 186
GLU A 332
 None
BGC  A 479 (-2.9A)
None
BGC  A 479 ( 4.9A)
 1.30A 3galB-3qomA:
undetectable		 3galB-3qomA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_C_DVAC6_0
(GRAMICIDIN D)		 3qom 6-PHOSPHO-BETA-GLUCO
SIDASE
(Lactobacillus
plantarum) 		3 / 3 ALA A 475
VAL A 469
TRP A  14
 None
 0.82A 3l8lC-3qomA:
undetectable
3l8lD-3qomA:
undetectable		 3l8lC-3qomA:
3.12
3l8lD-3qomA:
3.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_B_ACTB901_0
(PYRANOSE 2-OXIDASE)		 3qom 6-PHOSPHO-BETA-GLUCO
SIDASE
(Lactobacillus
plantarum) 		4 / 6 SER A 315
PHE A 135
HIS A 134
ASN A 179
 BGC  A 479 ( 3.8A)
None
None
None
 1.36A 3lskB-3qomA:
undetectable		 3lskB-3qomA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_2
(PROTEASE)		 3qom 6-PHOSPHO-BETA-GLUCO
SIDASE
(Lactobacillus
plantarum) 		5 / 9 GLY A 191
ILE A  39
GLY A 198
ILE A 199
ILE A  51
 None
 0.85A 3nu4B-3qomA:
undetectable		 3nu4B-3qomA:
10.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)		 3qom 6-PHOSPHO-BETA-GLUCO
SIDASE
(Lactobacillus
plantarum) 		4 / 5 ASP A 427
GLU A 447
TYR A 444
ASP A 382
 None
 1.38A 3w9tD-3qomA:
undetectable		 3w9tD-3qomA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_C_VK3C202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 3qom 6-PHOSPHO-BETA-GLUCO
SIDASE
(Lactobacillus
plantarum) 		4 / 7 ARG A 439
LEU A 455
ASN A 448
TYR A  60
 None
 1.14A 4f8yC-3qomA:
undetectable
4f8yD-3qomA:
undetectable		 4f8yC-3qomA:
16.80
4f8yD-3qomA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_F_CAMF502_0
(CAMPHOR
5-MONOOXYGENASE)		 3qom 6-PHOSPHO-BETA-GLUCO
SIDASE
(Lactobacillus
plantarum) 		4 / 4 TYR A 420
THR A 400
VAL A 469
ILE A 406
 None
 0.97A 4jx1F-3qomA:
undetectable		 4jx1F-3qomA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGV_A_ZITA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3qom 6-PHOSPHO-BETA-GLUCO
SIDASE
(Lactobacillus
plantarum) 		5 / 12 ILE A 238
GLY A 229
ALA A 221
SER A  91
ILE A  92
 None
 1.17A 5igvA-3qomA:
undetectable		 5igvA-3qomA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_A_SUEA1202_0
(NS3 PROTEASE)		 3qom 6-PHOSPHO-BETA-GLUCO
SIDASE
(Lactobacillus
plantarum) 		5 / 12 GLY A 229
VAL A 163
LEU A 304
GLY A 307
ALA A 221
 None
 1.02A 6c2mA-3qomA:
undetectable		 6c2mA-3qomA:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CNJ_D_NCTD402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 3qom 6-PHOSPHO-BETA-GLUCO
SIDASE
(Lactobacillus
plantarum) 		4 / 8 TYR A 157
TRP A  94
TRP A 148
LEU A 141
 None
 1.32A 6cnjD-3qomA:
undetectable
6cnjE-3qomA:
undetectable		 6cnjD-3qomA:
9.36
6cnjE-3qomA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CNK_B_NCTB402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 3qom 6-PHOSPHO-BETA-GLUCO
SIDASE
(Lactobacillus
plantarum) 		4 / 7 TYR A 157
TRP A  94
TRP A 148
LEU A 141
 None
 1.40A 6cnkB-3qomA:
undetectable
6cnkC-3qomA:
undetectable		 6cnkB-3qomA:
9.36
6cnkC-3qomA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3qom 6-PHOSPHO-BETA-GLUCO
SIDASE
(Lactobacillus
plantarum) 		3 / 3 ARG A 457
PHE A 442
PHE A  69
 None
 1.08A 6nknC-3qomA:
undetectable
6nknJ-3qomA:
undetectable		 6nknC-3qomA:
19.66
6nknJ-3qomA:
10.46