SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qp4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_A_ADNA1_1
(YTAA PROTEIN)		 3qp4 CVIR TRANSCRIPTIONAL
REGULATOR
(Chromobacterium
violaceum) 		4 / 7 PRO A 161
TRP A 111
ILE A 139
ILE A 156
 None
HL0  A   1 (-4.1A)
None
None
 0.88A 2q83A-3qp4A:
undetectable		 2q83A-3qp4A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_X_CPFX1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 3qp4 CVIR TRANSCRIPTIONAL
REGULATOR
(Chromobacterium
violaceum) 		4 / 4 ARG A 159
GLY A 138
GLU A 112
SER A  79
 None
 1.23A 2xctS-3qp4A:
undetectable
2xctU-3qp4A:
undetectable		 2xctS-3qp4A:
15.12
2xctU-3qp4A:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CV9_A_VDXA501_1
(CYTOCHROME P450-SU1)		 3qp4 CVIR TRANSCRIPTIONAL
REGULATOR
(Chromobacterium
violaceum) 		5 / 9 THR A 140
LEU A  60
ILE A 150
ILE A 102
GLY A 107
 None
 1.18A 3cv9A-3qp4A:
undetectable		 3cv9A-3qp4A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PP1_A_ACTA590_0
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 3qp4 CVIR TRANSCRIPTIONAL
REGULATOR
(Chromobacterium
violaceum) 		4 / 5 GLU A 146
LEU A  63
HIS A 179
GLY A 151
 None
 1.21A 3pp1A-3qp4A:
undetectable		 3pp1A-3qp4A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZMD_A_SALA201_1
(PUTATIVE
TRANSCRIPTIONAL
REGULATOR)		 3qp4 CVIR TRANSCRIPTIONAL
REGULATOR
(Chromobacterium
violaceum) 		4 / 8 ARG A  62
LEU A  63
GLU A 146
HIS A 179
 None
 1.06A 3zmdA-3qp4A:
undetectable
3zmdB-3qp4A:
undetectable		 3zmdA-3qp4A:
24.62
3zmdB-3qp4A:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_C_RTLC201_0
(RETINOL-BINDING
PROTEIN 2)		 3qp4 CVIR TRANSCRIPTIONAL
REGULATOR
(Chromobacterium
violaceum) 		5 / 12 ILE A 156
ALA A  51
SER A  79
LEU A  56
LEU A 178
 None
 1.48A 4qztC-3qp4A:
undetectable		 4qztC-3qp4A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_E_MFXE2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3qp4 CVIR TRANSCRIPTIONAL
REGULATOR
(Chromobacterium
violaceum) 		4 / 5 SER A  79
ARG A 159
GLY A 138
GLU A 112
 None
 0.96A 5cdqA-3qp4A:
undetectable
5cdqB-3qp4A:
undetectable
5cdqC-3qp4A:
undetectable		 5cdqA-3qp4A:
15.47
5cdqB-3qp4A:
22.02
5cdqC-3qp4A:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_V_MFXV2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3qp4 CVIR TRANSCRIPTIONAL
REGULATOR
(Chromobacterium
violaceum) 		4 / 5 SER A  79
ARG A 159
GLY A 138
GLU A 112
 None
 0.95A 5cdqR-3qp4A:
undetectable
5cdqS-3qp4A:
undetectable
5cdqT-3qp4A:
undetectable		 5cdqR-3qp4A:
15.47
5cdqS-3qp4A:
22.02
5cdqT-3qp4A:
15.47