SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qp6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_1
(ESTROGEN RECEPTOR)		 3qp6 CVIR TRANSCRIPTIONAL
REGULATOR
(Chromobacterium
violaceum) 		5 / 12 THR A 175
ALA A 143
LEU A 104
ILE A 185
LEU A  58
 None
 1.05A 1errA-3qp6A:
undetectable		 1errA-3qp6A:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_1
(ESTROGEN RECEPTOR)		 3qp6 CVIR TRANSCRIPTIONAL
REGULATOR
(Chromobacterium
violaceum) 		5 / 12 THR A 175
ALA A 143
LEU A 104
ILE A 185
LEU A  58
 None
 1.04A 2jfaA-3qp6A:
undetectable		 2jfaA-3qp6A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_1
(ESTROGEN RECEPTOR)		 3qp6 CVIR TRANSCRIPTIONAL
REGULATOR
(Chromobacterium
violaceum) 		5 / 12 THR A 175
ALA A 143
LEU A 104
ILE A 185
LEU A  58
 None
 1.03A 2qxsA-3qp6A:
undetectable		 2qxsA-3qp6A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_1
(ESTROGEN RECEPTOR)		 3qp6 CVIR TRANSCRIPTIONAL
REGULATOR
(Chromobacterium
violaceum) 		5 / 12 THR A 175
ALA A 143
LEU A 104
ILE A 185
LEU A  58
 None
 1.13A 2qxsB-3qp6A:
undetectable		 2qxsB-3qp6A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 3qp6 CVIR TRANSCRIPTIONAL
REGULATOR
(Chromobacterium
violaceum) 		4 / 8 ILE A  69
ASN A  67
ARG A  10
SER A 152
 None
 1.04A 2zw9B-3qp6A:
undetectable		 2zw9B-3qp6A:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_B_FLPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3qp6 CVIR TRANSCRIPTIONAL
REGULATOR
(Chromobacterium
violaceum) 		5 / 12 LEU A  63
LEU A  60
GLY A 105
ALA A 143
SER A 142
 None
 1.12A 5jvzB-3qp6A:
undetectable		 5jvzB-3qp6A:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_A_ACTA703_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 3qp6 CVIR TRANSCRIPTIONAL
REGULATOR
(Chromobacterium
violaceum) 		4 / 6 ARG A 117
ALA A 118
PRO A  98
GLU A 112
 None
 1.41A 5odqA-3qp6A:
undetectable		 5odqA-3qp6A:
17.07