SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qp8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_1
(ESTROGEN RECEPTOR)		 3qp8 CVIR TRANSCRIPTIONAL
REGULATOR
(Chromobacterium
violaceum) 		5 / 12 THR A 175
ALA A 143
LEU A 104
ILE A 185
LEU A  58
 None
 1.07A 1errA-3qp8A:
undetectable		 1errA-3qp8A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1301_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 3qp8 CVIR TRANSCRIPTIONAL
REGULATOR
(Chromobacterium
violaceum) 		4 / 6 LEU A  40
PHE A  43
ALA A  42
LEU A  76
 None
 1.01A 1ukbA-3qp8A:
undetectable		 1ukbA-3qp8A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_1
(ESTROGEN RECEPTOR)		 3qp8 CVIR TRANSCRIPTIONAL
REGULATOR
(Chromobacterium
violaceum) 		5 / 12 THR A 175
ALA A 143
LEU A 104
ILE A 185
LEU A  58
 None
 1.08A 2jfaA-3qp8A:
undetectable		 2jfaA-3qp8A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA608_1
(CHITINASE A)		 3qp8 CVIR TRANSCRIPTIONAL
REGULATOR
(Chromobacterium
violaceum) 		4 / 6 ASN A 148
SER A 145
ALA A 144
HIS A 179
 None
 1.21A 3aruA-3qp8A:
undetectable		 3aruA-3qp8A:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUK_A_RBFA201_1
(BLUE-LIGHT
PHOTORECEPTOR)		 3qp8 CVIR TRANSCRIPTIONAL
REGULATOR
(Chromobacterium
violaceum) 		5 / 12 VAL A 109
ARG A 101
GLN A  68
LEU A 104
ILE A 153
 None
 1.18A 4kukA-3qp8A:
2.5		 4kukA-3qp8A:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_B_FLPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3qp8 CVIR TRANSCRIPTIONAL
REGULATOR
(Chromobacterium
violaceum) 		5 / 12 LEU A  63
LEU A  60
GLY A 105
ALA A 143
SER A 142
 None
 1.12A 5jvzB-3qp8A:
undetectable		 5jvzB-3qp8A:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		 3qp8 CVIR TRANSCRIPTIONAL
REGULATOR
(Chromobacterium
violaceum) 		5 / 12 ILE A  47
LEU A  48
LEU A 178
THR A 175
LEU A 154
 None
 1.22A 5tiwA-3qp8A:
undetectable		 5tiwA-3qp8A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CK2_C_IPHC101_0
(INSULIN A CHAIN
INSULIN B CHAIN)		 3qp8 CVIR TRANSCRIPTIONAL
REGULATOR
(Chromobacterium
violaceum) 		4 / 4 ILE A  47
LEU A  40
HIS A 177
ALA A 181
 None
 0.94A 6ck2C-3qp8A:
undetectable
6ck2D-3qp8A:
undetectable		 6ck2C-3qp8A:
5.98
6ck2D-3qp8A:
12.41