SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qpi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)		 3qpi CHLORITE DISMUTASE
(Nitrobacter
winogradskyi) 		4 / 7 HIS A 131
LEU A 129
TYR A  61
ILE A  90
 None
HEM  A1001 ( 4.6A)
HEM  A1001 (-4.5A)
HEM  A1001 ( 4.0A)
 1.02A 1tuvA-3qpiA:
4.6		 1tuvA-3qpiA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_A_URFA999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 3qpi CHLORITE DISMUTASE
(Nitrobacter
winogradskyi) 		4 / 5 ALA A 124
TYR A 121
ILE A 125
ASP A 157
 None
None
HEM  A1001 ( 4.3A)
None
 1.11A 1upfA-3qpiA:
undetectable		 1upfA-3qpiA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_C_URFC999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 3qpi CHLORITE DISMUTASE
(Nitrobacter
winogradskyi) 		4 / 5 ALA A 124
TYR A 121
ILE A 125
ASP A 157
 None
None
HEM  A1001 ( 4.3A)
None
 0.98A 1upfC-3qpiA:
undetectable		 1upfC-3qpiA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3qpi CHLORITE DISMUTASE
(Nitrobacter
winogradskyi) 		4 / 8 PHE A 145
ILE A  88
PHE A 155
GLY A 160
 HEM  A1001 (-3.9A)
HEM  A1001 ( 4.0A)
None
None
 0.83A 2qx4A-3qpiA:
undetectable
2qx4B-3qpiA:
undetectable		 2qx4A-3qpiA:
21.43
2qx4B-3qpiA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VPP_A_GEOA1210_1
(DEOXYNUCLEOSIDE
KINASE)		 3qpi CHLORITE DISMUTASE
(Nitrobacter
winogradskyi) 		5 / 12 ILE A  88
ARG A 178
ALA A 152
PHE A 155
GLU A 174
 HEM  A1001 ( 4.0A)
None
None
None
None
 1.33A 2vppA-3qpiA:
undetectable		 2vppA-3qpiA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VPP_B_GEOB1207_1
(DEOXYNUCLEOSIDE
KINASE)		 3qpi CHLORITE DISMUTASE
(Nitrobacter
winogradskyi) 		5 / 12 ILE A  88
ARG A 178
ALA A 152
PHE A 155
GLU A 174
 HEM  A1001 ( 4.0A)
None
None
None
None
 1.31A 2vppB-3qpiA:
undetectable		 2vppB-3qpiA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3qpi CHLORITE DISMUTASE
(Nitrobacter
winogradskyi) 		5 / 12 PHE A 155
SER A 118
HIS A 114
LEU A  70
LEU A 162
 None
HEM  A1001 (-4.1A)
HEM  A1001 (-3.3A)
HEM  A1001 (-4.9A)
HEM  A1001 (-4.9A)
 1.41A 3adsA-3qpiA:
undetectable		 3adsA-3qpiA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3qpi CHLORITE DISMUTASE
(Nitrobacter
winogradskyi) 		3 / 3 LEU A  52
TRP A  14
TYR A 130
 None
 0.91A 3aicF-3qpiA:
undetectable		 3aicF-3qpiA:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3qpi CHLORITE DISMUTASE
(Nitrobacter
winogradskyi) 		3 / 3 LEU A  52
TRP A  14
TYR A 130
 None
 0.85A 3aicG-3qpiA:
undetectable		 3aicG-3qpiA:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3qpi CHLORITE DISMUTASE
(Nitrobacter
winogradskyi) 		3 / 3 LEU A  52
TRP A  14
TYR A 130
 None
 0.85A 3aicH-3qpiA:
undetectable		 3aicH-3qpiA:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VM4_A_IZPA1_1
(FATTY ACID
ALPHA-HYDROXYLASE)		 3qpi CHLORITE DISMUTASE
(Nitrobacter
winogradskyi) 		4 / 5 LEU A  17
ARG A  84
PRO A 149
ALA A 152
 None
 1.12A 3vm4A-3qpiA:
undetectable		 3vm4A-3qpiA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2D_F_LFXF102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 3qpi CHLORITE DISMUTASE
(Nitrobacter
winogradskyi) 		3 / 4 ARG A  53
GLY A  54
GLU A 137
 None
 0.67A 4z2dB-3qpiA:
undetectable
4z2dC-3qpiA:
undetectable		 4z2dB-3qpiA:
18.04
4z2dC-3qpiA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M50_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 3qpi CHLORITE DISMUTASE
(Nitrobacter
winogradskyi) 		5 / 12 ASP A 176
GLU A 174
LEU A 122
ARG A 163
GLY A 160
 None
None
HEM  A1001 ( 4.7A)
None
None
 1.24A 5m50E-3qpiA:
undetectable		 5m50E-3qpiA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_F_BEZF201_0
(NS3 PROTEASE)		 3qpi CHLORITE DISMUTASE
(Nitrobacter
winogradskyi) 		4 / 5 HIS A 114
ALA A 117
SER A 118
TYR A 121
 HEM  A1001 (-3.3A)
None
HEM  A1001 (-4.1A)
None
 1.30A 5yodF-3qpiA:
undetectable		 5yodF-3qpiA:
23.83