SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qpq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2INE_A_PACA317_0
(ALDOSE REDUCTASE)		 3qpq C1068 HEAVY CHAIN
(Homo
sapiens;
Mus
musculus) 		4 / 5 TRP H  33
VAL H  99
HIS H  35
TRP H  47
 None
 1.42A 2ineA-3qpqH:
undetectable		 2ineA-3qpqH:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ISF_A_PACA317_0
(ALDOSE REDUCTASE)		 3qpq C1068 HEAVY CHAIN
(Homo
sapiens;
Mus
musculus) 		4 / 5 TRP H  33
VAL H  99
HIS H  35
TRP H  47
 None
 1.40A 2isfA-3qpqH:
undetectable		 2isfA-3qpqH:
20.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M7K_H_ACTH302_0
(10H10 HEAVY CHAIN)		 3qpq C1068 HEAVY CHAIN
(Homo
sapiens;
Mus
musculus) 		4 / 5 VAL H   2
TYR H  27
ARG H  98
TYR H 108
 PCA  H   1 ( 3.4A)
None
None
None
 0.25A 4m7kH-3qpqH:
23.4		 4m7kH-3qpqH:
80.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_1
(CYTOCHROME P450 1A1)		 3qpq C1068 HEAVY CHAIN
(Homo
sapiens;
Mus
musculus) 		4 / 7 GLY H   8
ALA H   9
VAL H  18
LEU H  20
 None
 0.80A 6dwnB-3qpqH:
undetectable		 6dwnB-3qpqH:
16.97