SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qpt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KI7_A_ID2A1_0
(THYMIDINE KINASE)		 3qpt TRANSCRIPTIONAL
REGULATOR SLYA
(Salmonella
enterica) 		5 / 12 GLU A  71
ILE A  90
ILE A  40
ALA A  96
ARG A  78
 None
 1.47A 1ki7A-3qptA:
undetectable		 1ki7A-3qptA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYO_A_LNLA1216_1
(LIPOPROTEIN LPPX)		 3qpt TRANSCRIPTIONAL
REGULATOR SLYA
(Salmonella
enterica) 		4 / 5 LEU A  12
ILE A  15
LEU A  19
ARG A  23
 None
 0.92A 2byoA-3qptA:
undetectable		 2byoA-3qptA:
24.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_A_ADNA1_1
(YTAA PROTEIN)		 3qpt TRANSCRIPTIONAL
REGULATOR SLYA
(Salmonella
enterica) 		4 / 7 ILE A 130
ILE A 118
LEU A 115
ILE A 123
 None
 0.84A 2q83A-3qptA:
undetectable		 2q83A-3qptA:
21.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DEU_A_SALA301_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 3qpt TRANSCRIPTIONAL
REGULATOR SLYA
(Salmonella
enterica) 		5 / 6 TRP A  16
ARG A  17
ILE A  20
TRP A  34
VAL A  35
 None
 0.88A 3deuA-3qptA:
17.3		 3deuA-3qptA:
94.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DEU_A_SALA301_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 3qpt TRANSCRIPTIONAL
REGULATOR SLYA
(Salmonella
enterica) 		5 / 6 TRP A  16
ILE A  20
TRP A  34
VAL A  35
HIS A  38
 None
 0.71A 3deuA-3qptA:
17.3		 3deuA-3qptA:
94.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DEU_A_SALA305_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 3qpt TRANSCRIPTIONAL
REGULATOR SLYA
(Salmonella
enterica) 		4 / 7 THR A  32
VAL A  35
THR A  36
THR A  66
 None
 0.38A 3deuA-3qptA:
17.3		 3deuA-3qptA:
94.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DEU_A_SALA305_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 3qpt TRANSCRIPTIONAL
REGULATOR SLYA
(Salmonella
enterica) 		5 / 7 VAL A  35
THR A  36
ILE A  56
ILE A  58
SER A  62
 None
 0.90A 3deuA-3qptA:
17.3		 3deuA-3qptA:
94.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DEU_A_SALA305_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 3qpt TRANSCRIPTIONAL
REGULATOR SLYA
(Salmonella
enterica) 		5 / 7 VAL A  35
THR A  36
ILE A  56
SER A  62
THR A  66
 None
 0.99A 3deuA-3qptA:
17.3		 3deuA-3qptA:
94.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DEU_B_SALB302_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 3qpt TRANSCRIPTIONAL
REGULATOR SLYA
(Salmonella
enterica) 		4 / 5 TRP A  16
ARG A  17
ILE A  20
VAL A  35
 None
 0.82A 3deuB-3qptA:
17.4		 3deuB-3qptA:
94.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DEU_B_SALB302_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 3qpt TRANSCRIPTIONAL
REGULATOR SLYA
(Salmonella
enterica) 		4 / 5 TRP A  16
ILE A  20
VAL A  35
HIS A  38
 None
 0.57A 3deuB-3qptA:
17.4		 3deuB-3qptA:
94.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DEU_B_SALB306_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 3qpt TRANSCRIPTIONAL
REGULATOR SLYA
(Salmonella
enterica) 		5 / 6 THR A  32
THR A  36
SER A  62
LEU A  63
THR A  66
 None
 0.71A 3deuB-3qptA:
17.4		 3deuB-3qptA:
94.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DEU_B_SALB306_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 3qpt TRANSCRIPTIONAL
REGULATOR SLYA
(Salmonella
enterica) 		5 / 6 THR A  36
ILE A  58
SER A  62
LEU A  63
THR A  66
 None
 0.73A 3deuB-3qptA:
17.4		 3deuB-3qptA:
94.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q1E_C_T44C128_1
(5-HYDROXYISOURATE
HYDROLASE)		 3qpt TRANSCRIPTIONAL
REGULATOR SLYA
(Salmonella
enterica) 		4 / 6 LEU A  24
LEU A  27
LEU A  70
LEU A  75
 None
 0.98A 3q1eA-3qptA:
undetectable
3q1eC-3qptA:
undetectable		 3q1eA-3qptA:
20.67
3q1eC-3qptA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q1E_C_T44C128_1
(5-HYDROXYISOURATE
HYDROLASE)		 3qpt TRANSCRIPTIONAL
REGULATOR SLYA
(Salmonella
enterica) 		4 / 6 LEU A  70
LEU A  75
LEU A  24
LEU A  27
 None
 1.06A 3q1eA-3qptA:
undetectable
3q1eC-3qptA:
undetectable		 3q1eA-3qptA:
20.67
3q1eC-3qptA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3qpt TRANSCRIPTIONAL
REGULATOR SLYA
(Salmonella
enterica) 		4 / 8 HIS A 108
GLU A 113
ILE A  20
TRP A  16
 None
 1.34A 4cx7A-3qptA:
undetectable
4cx7B-3qptA:
undetectable		 4cx7A-3qptA:
16.28
4cx7B-3qptA:
16.28