SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qq8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_B_ZMRB466_2
(NEURAMINIDASE)		 3qq8 TRANSITIONAL
ENDOPLASMIC
RETICULUM ATPASE
(Homo
sapiens) 		3 / 3 ASP A  29
ARG A  83
ILE A  32
 None
 0.76A 1a4gB-3qq8A:
undetectable		 1a4gB-3qq8A:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_1
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 3qq8 TRANSITIONAL
ENDOPLASMIC
RETICULUM ATPASE
(Homo
sapiens) 		3 / 3 SER A  73
ASP A  79
ASP A  47
 None
 0.69A 2plwA-3qq8A:
undetectable		 2plwA-3qq8A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3REM_A_SALA301_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 3qq8 TRANSITIONAL
ENDOPLASMIC
RETICULUM ATPASE
(Homo
sapiens) 		4 / 8 VAL A  39
ARG A  89
VAL A  94
ILE A 100
 None
 1.01A 3remA-3qq8A:
undetectable		 3remA-3qq8A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3REM_A_SALA301_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 3qq8 TRANSITIONAL
ENDOPLASMIC
RETICULUM ATPASE
(Homo
sapiens) 		4 / 8 VAL A  68
VAL A 176
TYR A 173
ILE A 146
 None
 1.06A 3remA-3qq8A:
undetectable		 3remA-3qq8A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3REM_B_SALB301_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 3qq8 TRANSITIONAL
ENDOPLASMIC
RETICULUM ATPASE
(Homo
sapiens) 		4 / 8 VAL A  39
ARG A  89
VAL A  94
ILE A 100
 None
 1.02A 3remB-3qq8A:
undetectable		 3remB-3qq8A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3qq8 TRANSITIONAL
ENDOPLASMIC
RETICULUM ATPASE
(Homo
sapiens) 		5 / 11 SER A  40
LEU A  41
ILE A  70
VAL A  57
VAL A  88
 None
 1.06A 3w67A-3qq8A:
undetectable		 3w67A-3qq8A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PST_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 3qq8 TRANSITIONAL
ENDOPLASMIC
RETICULUM ATPASE
(Homo
sapiens) 		3 / 3 ILE A  70
ASP A  35
ARG A  53
 None
 0.81A 4pstA-3qq8A:
undetectable		 4pstA-3qq8A:
24.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_ACTA502_0
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 3qq8 TRANSITIONAL
ENDOPLASMIC
RETICULUM ATPASE
(Homo
sapiens) 		4 / 4 LYS A  62
ARG A  93
GLY A  61
ASP A  98
 None
 1.21A 4ryaA-3qq8A:
0.0		 4ryaA-3qq8A:
17.54