SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qqi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_B_CCSB47_0
(GLUTATHIONE
S-TRANSFERASE)		 3qqi HEMAGGLUTININ
(Influenza
A
virus) 		4 / 7 LEU A 194
THR A 155
LEU A 251
GLY A 249
 None
EPE  A3380 ( 3.7A)
None
None
 0.81A 1gtiB-3qqiA:
undetectable		 1gtiB-3qqiA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 3qqi HEMAGGLUTININ
(Influenza
A
virus) 		5 / 10 LEU A  61
ILE A 267
SER A 265
SER A  85
GLY A 266
 None
 1.29A 3ijxB-3qqiA:
undetectable
3ijxD-3qqiA:
undetectable		 3ijxB-3qqiA:
19.00
3ijxD-3qqiA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 3qqi HEMAGGLUTININ
(Influenza
A
virus) 		5 / 10 LEU A  61
ILE A 267
SER A 265
SER A  85
GLY A 266
 None
 1.32A 3ik6B-3qqiA:
undetectable
3ik6E-3qqiA:
undetectable		 3ik6B-3qqiA:
19.00
3ik6E-3qqiA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_B_HFZB800_1
(GLUTAMATE RECEPTOR 2)		 3qqi HEMAGGLUTININ
(Influenza
A
virus) 		5 / 10 LEU A  61
ILE A 267
SER A 265
SER A  85
GLY A 266
 None
 1.26A 3iluB-3qqiA:
undetectable
3iluE-3qqiA:
undetectable		 3iluB-3qqiA:
19.00
3iluE-3qqiA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_E_HFZE800_1
(GLUTAMATE RECEPTOR 2)		 3qqi HEMAGGLUTININ
(Influenza
A
virus) 		5 / 11 ILE A 267
SER A 265
SER A  85
GLY A 266
LEU A  61
 None
 1.30A 3iluB-3qqiA:
undetectable
3iluE-3qqiA:
undetectable		 3iluB-3qqiA:
19.00
3iluE-3qqiA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3qqi HEMAGGLUTININ
(Influenza
A
virus) 		4 / 8 ILE A 120
LEU A 121
VAL A 204
GLY A 205
 None
 0.86A 3w1wA-3qqiA:
undetectable		 3w1wA-3qqiA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_A_SALA601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3qqi HEMAGGLUTININ
(Influenza
A
virus) 		4 / 7 LEU A 194
TYR A 195
ILE A 252
GLY A 134
 None
None
None
EPE  A3380 (-3.4A)
 0.77A 4eq4A-3qqiA:
undetectable		 4eq4A-3qqiA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3qqi HEMAGGLUTININ
(Influenza
A
virus) 		4 / 7 LEU A 194
TYR A 195
ILE A 252
GLY A 134
 None
None
None
EPE  A3380 (-3.4A)
 0.78A 4eqlA-3qqiA:
undetectable		 4eqlA-3qqiA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_B_SALB602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3qqi HEMAGGLUTININ
(Influenza
A
virus) 		4 / 7 LEU A 194
TYR A 195
ILE A 252
GLY A 134
 None
None
None
EPE  A3380 (-3.4A)
 0.78A 4eqlB-3qqiA:
undetectable		 4eqlB-3qqiA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HOJ_A_ACTA303_0
(REGF PROTEIN)		 3qqi HEMAGGLUTININ
(Influenza
A
virus) 		4 / 5 VAL A 115
ARG A 263
GLU A 174
LEU A 236
 None
 1.25A 4hojA-3qqiA:
undetectable		 4hojA-3qqiA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3qqi HEMAGGLUTININ
(Influenza
A
virus) 		4 / 6 LEU A 194
TYR A 195
ILE A 252
GLY A 134
 None
None
None
EPE  A3380 (-3.4A)
 0.82A 4l39A-3qqiA:
undetectable		 4l39A-3qqiA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3qqi HEMAGGLUTININ
(Influenza
A
virus) 		4 / 7 LEU A 194
TYR A 195
ILE A 252
GLY A 134
 None
None
None
EPE  A3380 (-3.4A)
 0.81A 4l39B-3qqiA:
undetectable		 4l39B-3qqiA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_F_MFXF2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3qqi HEMAGGLUTININ
(Influenza
A
virus) 		4 / 6 ARG A  78
ASP A  77
ARG A 149
GLY A  72
 None
 1.05A 5cdqA-3qqiA:
undetectable
5cdqC-3qqiA:
undetectable
5cdqD-3qqiA:
undetectable		 5cdqA-3qqiA:
18.67
5cdqC-3qqiA:
18.67
5cdqD-3qqiA:
20.68