SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qqm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QVT_A_PRLA311_0 (TRANSCRIPTIONAL REGULATOR QACR)	3qqm	MLR3007 PROTEIN (Mesorhizobium loti)	4 / 8	GLU A 150 GLU A 138 THR A 105 ILE A 148	LLP A 117 ( 3.4A) EDO A 275 (-3.6A) None None	1.02A	1qvtA-3qqmA: undetectable	1qvtA-3qqmA: 17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZLQ_A_ACTA1502_0 (NICKEL-BINDING PERIPLASMIC PROTEIN)	3qqm	MLR3007 PROTEIN (Mesorhizobium loti)	4 / 5	TRP A 98 GLY A 208 ASN A 209 GLY A 213	None None IOD A 234 (-4.1A) IOD A 225 ( 3.9A)	1.17A	1zlqA-3qqmA: undetectable	1zlqA-3qqmA: 20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VL2_B_BEZB1162_0 (PEROXIREDOXIN-5)	3qqm	MLR3007 PROTEIN (Mesorhizobium loti)	4 / 7	GLY A 10 LEU A 46 PHE A 48 THR A 118	None CL A 250 (-4.3A) None EDO A 270 (-2.7A)	1.03A	2vl2B-3qqmA: undetectable	2vl2B-3qqmA: 23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SMT_A_ACTA1001_0 (HISTONE-LYSINE N-METHYLTRANSFERASE SETD3)	3qqm	MLR3007 PROTEIN (Mesorhizobium loti)	4 / 5	LEU A 46 GLY A 47 PHE A 48 PHE A 15	CL A 250 (-4.3A) None None None	1.08A	3smtA-3qqmA: undetectable	3smtA-3qqmA: 20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VYW_C_SAMC401_0 (MNMC2)	3qqm	MLR3007 PROTEIN (Mesorhizobium loti)	5 / 12	TYR A 196 GLY A 151 GLY A 208 ASN A 155 ALA A 127	None None None LLP A 117 ( 3.7A) None	1.13A	3vywC-3qqmA: undetectable	3vywC-3qqmA: 20.20

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1QVT_A_PRLA311_0","TRANSCRIPTIONAL REGULATOR QACR","3qqm","MLR3007 PROTEIN","Mesorhizobium loti",4,"GLU A 150;GLU A 138;THR A 105;ILE A 148","LLP A 117 ( 3.4A);EDO A 275 (-3.6A);None;None","1.02A","1qvtA-3qqmA:undetectable","1qvtA-3qqmA:17.39"],["1ZLQ_A_ACTA1502_0","NICKEL-BINDING PERIPLASMIC PROTEIN","3qqm","MLR3007 PROTEIN","Mesorhizobium loti",4,"TRP A  98;GLY A 208;ASN A 209;GLY A 213","None;None;IOD A 234 (-4.1A);IOD A 225 ( 3.9A)","1.17A","1zlqA-3qqmA:undetectable","1zlqA-3qqmA:20.37"],["2VL2_B_BEZB1162_0","PEROXIREDOXIN-5","3qqm","MLR3007 PROTEIN","Mesorhizobium loti",4,"GLY A  10;LEU A  46;PHE A  48;THR A 118","None; CL A 250 (-4.3A);None;EDO A 270 (-2.7A)","1.03A","2vl2B-3qqmA:undetectable","2vl2B-3qqmA:23.73"],["3SMT_A_ACTA1001_0","HISTONE-LYSINE N-METHYLTRANSFERASE SETD3","3qqm","MLR3007 PROTEIN","Mesorhizobium loti",4,"LEU A  46;GLY A  47;PHE A  48;PHE A  15"," CL A 250 (-4.3A);None;None;None","1.08A","3smtA-3qqmA:undetectable","3smtA-3qqmA:20.72"],["3VYW_C_SAMC401_0","MNMC2","3qqm","MLR3007 PROTEIN","Mesorhizobium loti",5,"TYR A 196;GLY A 151;GLY A 208;ASN A 155;ALA A 127","None;None;None;LLP A 117 ( 3.7A);None","1.13A","3vywC-3qqmA:undetectable","3vywC-3qqmA:20.20"]]