SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qqr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 3qqr NON-LEGUME
HEMOGLOBIN
(Parasponia
andersonii) 		4 / 7 PHE A  36
PHE A  37
PHE A  51
VAL A  74
 None
None
HEM  A 163 (-3.8A)
HEM  A 163 ( 4.4A)
 0.83A 1lh6A-3qqrA:
19.6		 1lh6A-3qqrA:
41.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 3qqr NON-LEGUME
HEMOGLOBIN
(Parasponia
andersonii) 		4 / 7 PHE A  36
PHE A  37
VAL A  74
HIS A 105
 None
None
HEM  A 163 ( 4.4A)
HEM  A 163 (-3.1A)
 0.80A 1lh6A-3qqrA:
19.6		 1lh6A-3qqrA:
41.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 3qqr NON-LEGUME
HEMOGLOBIN
(Parasponia
andersonii) 		4 / 7 PHE A  37
PHE A  51
VAL A  74
HIS A 105
 None
HEM  A 163 (-3.8A)
HEM  A 163 ( 4.4A)
HEM  A 163 (-3.1A)
 0.79A 1lh6A-3qqrA:
19.6		 1lh6A-3qqrA:
41.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_2
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3qqr NON-LEGUME
HEMOGLOBIN
(Parasponia
andersonii) 		3 / 3 ASN A  28
ILE A 126
MET A 133
 None
 0.65A 2h42C-3qqrA:
undetectable		 2h42C-3qqrA:
19.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 3qqr NON-LEGUME
HEMOGLOBIN
(Parasponia
andersonii) 		4 / 5 PHE A  36
PHE A  37
PHE A  51
VAL A  74
 None
None
HEM  A 163 (-3.8A)
HEM  A 163 ( 4.4A)
 0.82A 2lh6A-3qqrA:
19.6		 2lh6A-3qqrA:
41.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		 3qqr NON-LEGUME
HEMOGLOBIN
(Parasponia
andersonii) 		5 / 12 MET A 157
ILE A 153
LEU A 149
PHE A 115
THR A  73
 None
None
HEM  A 163 (-4.1A)
HEM  A 163 ( 4.3A)
HEM  A 163 (-4.0A)
 0.99A 5bykA-3qqrA:
undetectable		 5bykA-3qqrA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		 3qqr NON-LEGUME
HEMOGLOBIN
(Parasponia
andersonii) 		5 / 12 MET A 157
ILE A 153
LEU A 149
PHE A 115
THR A  73
 None
None
HEM  A 163 (-4.1A)
HEM  A 163 ( 4.3A)
HEM  A 163 (-4.0A)
 0.99A 6b52A-3qqrA:
undetectable		 6b52A-3qqrA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		 3qqr NON-LEGUME
HEMOGLOBIN
(Parasponia
andersonii) 		5 / 12 MET A 157
ILE A 153
LEU A 149
PHE A 115
THR A  73
 None
None
HEM  A 163 (-4.1A)
HEM  A 163 ( 4.3A)
HEM  A 163 (-4.0A)
 0.95A 6b54A-3qqrA:
undetectable		 6b54A-3qqrA:
19.69