SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qqw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXD_A_DR7A102_1
(POL PROTEIN)		 3qqw PUTATIVE CITRATE
LYASE
(Cupriavidus
pinatubonensis) 		5 / 11 ILE A  74
LEU A 111
ALA A 136
ILE A 129
VAL A 104
 None
 1.11A 2fxdA-3qqwA:
undetectable		 2fxdA-3qqwA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL201_1
(PROTEIN S100-A4)		 3qqw PUTATIVE CITRATE
LYASE
(Cupriavidus
pinatubonensis) 		4 / 7 GLY A 182
MET A 210
PHE A 246
PHE A 248
 None
 1.00A 3ko0L-3qqwA:
undetectable
3ko0N-3qqwA:
undetectable		 3ko0L-3qqwA:
15.50
3ko0N-3qqwA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3qqw PUTATIVE CITRATE
LYASE
(Cupriavidus
pinatubonensis) 		3 / 3 TYR A 113
ASP A 173
ASP A 178
 None
 0.81A 3ou6B-3qqwA:
undetectable		 3ou6B-3qqwA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_B_MXMB606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3qqw PUTATIVE CITRATE
LYASE
(Cupriavidus
pinatubonensis) 		5 / 12 ILE A 151
VAL A 160
LEU A 157
ALA A 212
LEU A 172
 None
 1.02A 4m11B-3qqwA:
undetectable		 4m11B-3qqwA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_1
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 3qqw PUTATIVE CITRATE
LYASE
(Cupriavidus
pinatubonensis) 		3 / 3 ASP A  90
GLU A 127
SER A 181
 None
 0.71A 5bw4B-3qqwA:
undetectable		 5bw4B-3qqwA:
24.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNR_A_6J3A201_0
(TRANSTHYRETIN)		 3qqw PUTATIVE CITRATE
LYASE
(Cupriavidus
pinatubonensis) 		4 / 4 LYS A 207
LEU A 203
ALA A 206
LEU A 202
 None
 1.31A 6gnrA-3qqwA:
undetectable		 6gnrA-3qqwA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNR_B_6J3B201_0
(TRANSTHYRETIN)		 3qqw PUTATIVE CITRATE
LYASE
(Cupriavidus
pinatubonensis) 		4 / 4 LYS A 207
LEU A 203
ALA A 206
LEU A 202
 None
 1.30A 6gnrB-3qqwA:
undetectable		 6gnrB-3qqwA:
17.43