SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qqy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DYR_A_TOPA407_1
(DIHYDROFOLATE
REDUCTASE)
3qqy RIBOSOMAL PROTEIN
3/HOMING
ENDONUCLEASE-LIKE
PROTEIN FUSION

(Ophiostoma
novo-ulmi)
5 / 11 ILE A 216
LEU A 171
ILE A 202
PHE A 237
ILE A 249
None
1.00A 1dyrA-3qqyA:
undetectable
1dyrA-3qqyA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_Q_TRPQ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3qqy RIBOSOMAL PROTEIN
3/HOMING
ENDONUCLEASE-LIKE
PROTEIN FUSION

(Ophiostoma
novo-ulmi)
5 / 10 GLY A 127
HIS A 122
ILE A 125
THR A  41
SER A  35
None
1.20A 1utdQ-3qqyA:
undetectable
1utdR-3qqyA:
undetectable
1utdQ-3qqyA:
14.86
1utdR-3qqyA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZ1_A_HLTA2001_1
(FERRITIN LIGHT CHAIN)
3qqy RIBOSOMAL PROTEIN
3/HOMING
ENDONUCLEASE-LIKE
PROTEIN FUSION

(Ophiostoma
novo-ulmi)
4 / 4 LEU A 215
SER A 214
TYR A 218
LEU A 219
None
1.31A 1xz1A-3qqyA:
undetectable
1xz1A-3qqyA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZ3_A_ICFA201_1
(FERRITIN LIGHT CHAIN)
3qqy RIBOSOMAL PROTEIN
3/HOMING
ENDONUCLEASE-LIKE
PROTEIN FUSION

(Ophiostoma
novo-ulmi)
4 / 4 LEU A 215
SER A 214
TYR A 218
LEU A 219
None
1.30A 1xz3A-3qqyA:
undetectable
1xz3A-3qqyA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_A_RABA602_2
(ADENOSYLHOMOCYSTEINA
SE)
3qqy RIBOSOMAL PROTEIN
3/HOMING
ENDONUCLEASE-LIKE
PROTEIN FUSION

(Ophiostoma
novo-ulmi)
4 / 5 GLN A 102
THR A 101
GLU A 178
THR A 203
None
None
MG  A 304 (-4.0A)
None
1.40A 3glqA-3qqyA:
undetectable
3glqA-3qqyA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_A_9PLA501_1
(CYTOCHROME P450 2A6)
3qqy RIBOSOMAL PROTEIN
3/HOMING
ENDONUCLEASE-LIKE
PROTEIN FUSION

(Ophiostoma
novo-ulmi)
5 / 11 VAL A 252
PHE A 253
PHE A 237
GLY A 220
LEU A 171
None
0.99A 3t3rA-3qqyA:
undetectable
3t3rA-3qqyA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)
3qqy RIBOSOMAL PROTEIN
3/HOMING
ENDONUCLEASE-LIKE
PROTEIN FUSION

(Ophiostoma
novo-ulmi)
3 / 3 ASP A  53
ASN A  59
PHE A 303
None
0.74A 5jglB-3qqyA:
undetectable
5jglB-3qqyA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_1
(REGULATORY PROTEIN
TETR)
3qqy RIBOSOMAL PROTEIN
3/HOMING
ENDONUCLEASE-LIKE
PROTEIN FUSION

(Ophiostoma
novo-ulmi)
4 / 8 GLN A  46
GLY A  44
TRP A  64
ASP A  86
None
1.06A 5vlmD-3qqyA:
undetectable
5vlmD-3qqyA:
21.50