SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qqz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4001_1
(SERUM ALBUMIN)
3qqz PUTATIVE
UNCHARACTERIZED
PROTEIN YJIK

(Escherichia
coli)
5 / 9 LEU A 240
LEU A 280
VAL A 297
GLY A 296
ALA A 246
None
1.01A 1e7aA-3qqzA:
undetectable
1e7aA-3qqzA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_B_ESTB354_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)
3qqz PUTATIVE
UNCHARACTERIZED
PROTEIN YJIK

(Escherichia
coli)
4 / 8 SER A 244
VAL A 243
LEU A 240
VAL A 274
None
1.09A 1fduB-3qqzA:
undetectable
1fduB-3qqzA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)
3qqz PUTATIVE
UNCHARACTERIZED
PROTEIN YJIK

(Escherichia
coli)
5 / 12 ILE A 143
ALA A 195
GLY A 296
GLY A 245
LEU A 100
None
None
None
CA  A 327 ( 4.9A)
None
1.01A 1rjdA-3qqzA:
undetectable
1rjdA-3qqzA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)
3qqz PUTATIVE
UNCHARACTERIZED
PROTEIN YJIK

(Escherichia
coli)
5 / 12 ILE A 143
ALA A 195
GLY A 296
GLY A 245
LEU A 100
None
None
None
CA  A 327 ( 4.9A)
None
0.99A 1rjdB-3qqzA:
undetectable
1rjdB-3qqzA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)
3qqz PUTATIVE
UNCHARACTERIZED
PROTEIN YJIK

(Escherichia
coli)
5 / 12 ILE A 143
ALA A 195
GLY A 296
GLY A 245
LEU A 100
None
None
None
CA  A 327 ( 4.9A)
None
0.99A 1rjdC-3qqzA:
undetectable
1rjdC-3qqzA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
3qqz PUTATIVE
UNCHARACTERIZED
PROTEIN YJIK

(Escherichia
coli)
4 / 7 LEU A 234
GLN A 235
PHE A 238
LEU A 255
None
1.00A 1v55P-3qqzA:
undetectable
1v55W-3qqzA:
undetectable
1v55P-3qqzA:
22.58
1v55W-3qqzA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
3qqz PUTATIVE
UNCHARACTERIZED
PROTEIN YJIK

(Escherichia
coli)
4 / 7 LEU A 234
GLN A 235
PHE A 238
LEU A 255
None
0.91A 2dysC-3qqzA:
undetectable
2dysJ-3qqzA:
undetectable
2dysC-3qqzA:
22.58
2dysJ-3qqzA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
3qqz PUTATIVE
UNCHARACTERIZED
PROTEIN YJIK

(Escherichia
coli)
4 / 7 LEU A 234
GLN A 235
PHE A 238
LEU A 255
None
0.99A 2eijP-3qqzA:
undetectable
2eijW-3qqzA:
undetectable
2eijP-3qqzA:
22.58
2eijW-3qqzA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
3qqz PUTATIVE
UNCHARACTERIZED
PROTEIN YJIK

(Escherichia
coli)
4 / 5 ARG A 130
MET A 122
THR A 108
LEU A 109
None
1.23A 2eimJ-3qqzA:
undetectable
2eimJ-3qqzA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
3qqz PUTATIVE
UNCHARACTERIZED
PROTEIN YJIK

(Escherichia
coli)
4 / 5 ARG A 130
MET A 122
THR A 108
LEU A 109
None
1.27A 2eimW-3qqzA:
undetectable
2eimW-3qqzA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1001_0
(ALDEHYDE
DEHYDROGENASE A)
3qqz PUTATIVE
UNCHARACTERIZED
PROTEIN YJIK

(Escherichia
coli)
4 / 7 LEU A 287
PHE A  78
PHE A 317
ILE A 291
None
0.88A 2opxA-3qqzA:
undetectable
2opxA-3qqzA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3qqz PUTATIVE
UNCHARACTERIZED
PROTEIN YJIK

(Escherichia
coli)
4 / 7 LEU A 234
GLN A 235
PHE A 238
LEU A 255
None
0.94A 2zxwC-3qqzA:
undetectable
2zxwJ-3qqzA:
undetectable
2zxwC-3qqzA:
22.58
2zxwJ-3qqzA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
3qqz PUTATIVE
UNCHARACTERIZED
PROTEIN YJIK

(Escherichia
coli)
4 / 5 ILE A  97
ARG A 130
MET A 122
THR A 108
None
1.33A 3abkN-3qqzA:
undetectable
3abkW-3qqzA:
undetectable
3abkN-3qqzA:
18.34
3abkW-3qqzA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3qqz PUTATIVE
UNCHARACTERIZED
PROTEIN YJIK

(Escherichia
coli)
4 / 6 LEU A 234
GLN A 235
PHE A 238
LEU A 255
None
1.00A 3ag1C-3qqzA:
undetectable
3ag1J-3qqzA:
undetectable
3ag1C-3qqzA:
22.58
3ag1J-3qqzA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)
3qqz PUTATIVE
UNCHARACTERIZED
PROTEIN YJIK

(Escherichia
coli)
4 / 5 ARG A 130
MET A 122
THR A 108
LEU A 109
None
1.21A 3ag1J-3qqzA:
undetectable
3ag1J-3qqzA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)
3qqz PUTATIVE
UNCHARACTERIZED
PROTEIN YJIK

(Escherichia
coli)
4 / 5 ARG A 130
MET A 122
THR A 108
LEU A 109
None
1.27A 3ag2J-3qqzA:
undetectable
3ag2J-3qqzA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)
3qqz PUTATIVE
UNCHARACTERIZED
PROTEIN YJIK

(Escherichia
coli)
4 / 5 ARG A 130
MET A 122
THR A 108
LEU A 109
None
1.19A 3ag4J-3qqzA:
undetectable
3ag4J-3qqzA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_A_DX4A270_0
(PTERIDINE REDUCTASE
1)
3qqz PUTATIVE
UNCHARACTERIZED
PROTEIN YJIK

(Escherichia
coli)
4 / 6 ARG A 130
SER A 103
ASP A 148
PRO A 168
None
1.30A 3jqaA-3qqzA:
undetectable
3jqaA-3qqzA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_C_DX4C270_0
(PTERIDINE REDUCTASE
1)
3qqz PUTATIVE
UNCHARACTERIZED
PROTEIN YJIK

(Escherichia
coli)
4 / 6 ARG A 130
SER A 103
ASP A 148
PRO A 168
None
1.28A 3jqaC-3qqzA:
undetectable
3jqaC-3qqzA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_D_DX4D270_0
(PTERIDINE REDUCTASE
1)
3qqz PUTATIVE
UNCHARACTERIZED
PROTEIN YJIK

(Escherichia
coli)
4 / 6 ARG A 130
SER A 103
ASP A 148
PRO A 168
None
1.29A 3jqaD-3qqzA:
undetectable
3jqaD-3qqzA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KKZ_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN Q5LES9)
3qqz PUTATIVE
UNCHARACTERIZED
PROTEIN YJIK

(Escherichia
coli)
5 / 12 GLY A 296
GLY A 245
LEU A 100
LEU A 256
ALA A 294
None
CA  A 327 ( 4.9A)
None
None
None
1.13A 3kkzA-3qqzA:
undetectable
3kkzA-3qqzA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3qqz PUTATIVE
UNCHARACTERIZED
PROTEIN YJIK

(Escherichia
coli)
4 / 7 LEU A 234
GLN A 235
PHE A 238
LEU A 255
None
0.91A 3x2qC-3qqzA:
undetectable
3x2qJ-3qqzA:
undetectable
3x2qC-3qqzA:
22.58
3x2qJ-3qqzA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3qqz PUTATIVE
UNCHARACTERIZED
PROTEIN YJIK

(Escherichia
coli)
4 / 7 LEU A 234
GLN A 235
PHE A 238
LEU A 255
None
0.88A 3x2qP-3qqzA:
undetectable
3x2qW-3qqzA:
undetectable
3x2qP-3qqzA:
22.58
3x2qW-3qqzA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_B_T1CB392_1
(TETX2 PROTEIN)
3qqz PUTATIVE
UNCHARACTERIZED
PROTEIN YJIK

(Escherichia
coli)
5 / 11 PHE A 314
ASN A 312
GLY A  87
GLY A 296
GLU A 247
None
None
None
None
CA  A 324 (-3.1A)
1.43A 4a6nB-3qqzA:
undetectable
4a6nB-3qqzA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_A_ADNA401_1
(APH(2'')-ID)
3qqz PUTATIVE
UNCHARACTERIZED
PROTEIN YJIK

(Escherichia
coli)
5 / 11 GLY A 219
ILE A 178
PRO A 181
ILE A 180
ILE A 228
None
1.04A 4dt8A-3qqzA:
undetectable
4dt8A-3qqzA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_B_ADNB401_1
(APH(2'')-ID)
3qqz PUTATIVE
UNCHARACTERIZED
PROTEIN YJIK

(Escherichia
coli)
5 / 10 GLY A 219
ILE A 178
PRO A 181
ILE A 180
ILE A 228
None
1.06A 4dt8B-3qqzA:
undetectable
4dt8B-3qqzA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)
3qqz PUTATIVE
UNCHARACTERIZED
PROTEIN YJIK

(Escherichia
coli)
4 / 7 ASN A 114
GLU A 310
GLU A 141
GLU A 192
None
CA  A 325 ( 4.9A)
CA  A 325 ( 2.4A)
CA  A 326 (-2.2A)
1.37A 4mj8C-3qqzA:
undetectable
4mj8C-3qqzA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_H_SPMH202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)
3qqz PUTATIVE
UNCHARACTERIZED
PROTEIN YJIK

(Escherichia
coli)
4 / 6 ASN A 114
GLU A 310
GLU A 141
GLU A 192
None
CA  A 325 ( 4.9A)
CA  A 325 ( 2.4A)
CA  A 326 (-2.2A)
1.25A 4r87H-3qqzA:
undetectable
4r87H-3qqzA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIN_H_QI9H1226_0
(FAB 314.3)
3qqz PUTATIVE
UNCHARACTERIZED
PROTEIN YJIK

(Escherichia
coli)
5 / 12 TRP A 204
SER A 197
PHE A 206
GLY A 272
LEU A 270
None
1.14A 4uinH-3qqzA:
undetectable
4uinL-3qqzA:
undetectable
4uinH-3qqzA:
22.89
4uinL-3qqzA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3qqz PUTATIVE
UNCHARACTERIZED
PROTEIN YJIK

(Escherichia
coli)
4 / 5 ARG A 130
MET A 122
THR A 108
LEU A 109
None
1.35A 5w97J-3qqzA:
undetectable
5w97J-3qqzA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3qqz PUTATIVE
UNCHARACTERIZED
PROTEIN YJIK

(Escherichia
coli)
4 / 5 ARG A 130
MET A 122
THR A 108
LEU A 109
None
1.19A 5wauJ-3qqzA:
undetectable
5wauJ-3qqzA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3qqz PUTATIVE
UNCHARACTERIZED
PROTEIN YJIK

(Escherichia
coli)
4 / 5 ARG A 130
MET A 122
THR A 108
LEU A 109
None
1.31A 5x1bW-3qqzA:
undetectable
5x1bW-3qqzA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3qqz PUTATIVE
UNCHARACTERIZED
PROTEIN YJIK

(Escherichia
coli)
4 / 5 ARG A 130
MET A 122
THR A 108
LEU A 109
None
1.23A 5x1fW-3qqzA:
undetectable
5x1fW-3qqzA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3qqz PUTATIVE
UNCHARACTERIZED
PROTEIN YJIK

(Escherichia
coli)
4 / 7 LEU A 234
GLN A 235
PHE A 238
LEU A 255
None
0.94A 5z85C-3qqzA:
undetectable
5z85J-3qqzA:
undetectable
5z85C-3qqzA:
22.58
5z85J-3qqzA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3qqz PUTATIVE
UNCHARACTERIZED
PROTEIN YJIK

(Escherichia
coli)
4 / 7 LEU A 234
GLN A 235
PHE A 238
LEU A 255
None
0.92A 5zcoC-3qqzA:
undetectable
5zcoJ-3qqzA:
undetectable
5zcoC-3qqzA:
22.58
5zcoJ-3qqzA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3qqz PUTATIVE
UNCHARACTERIZED
PROTEIN YJIK

(Escherichia
coli)
4 / 7 LEU A 234
GLN A 235
PHE A 238
LEU A 255
None
0.95A 5zcqP-3qqzA:
undetectable
5zcqW-3qqzA:
undetectable
5zcqP-3qqzA:
22.58
5zcqW-3qqzA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_2
(SIALIDASE)
3qqz PUTATIVE
UNCHARACTERIZED
PROTEIN YJIK

(Escherichia
coli)
4 / 6 ASN A 290
LEU A 287
SER A 284
PHE A 317
None
1.21A 6ekuA-3qqzA:
8.9
6ekuA-3qqzA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3qqz PUTATIVE
UNCHARACTERIZED
PROTEIN YJIK

(Escherichia
coli)
4 / 5 ARG A 130
MET A 122
THR A 108
LEU A 109
None
1.23A 6nknJ-3qqzA:
undetectable
6nknJ-3qqzA:
12.24