SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qr1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_A_NOVA400_2
(DNA GYRASE SUBUNIT B)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		3 / 3 ASN A 126
PHE A  28
VAL A 129
 None
 0.76A 1kijA-3qr1A:
undetectable		 1kijA-3qr1A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW3_A_SAMA500_0
(HISTONE
METHYLTRANSFERASE
DOT1L)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		5 / 12 GLU A 136
ASP A  26
GLY A  25
VAL A 129
PHE A  28
 None
 1.29A 1nw3A-3qr1A:
undetectable		 1nw3A-3qr1A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_B_ADNB1502_1
(CLASS B ACID
PHOSPHATASE)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		4 / 7 PHE A 305
GLU A 282
TYR A 283
LEU A 279
 None
 1.10A 1rmtB-3qr1A:
undetectable		 1rmtB-3qr1A:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTF_A_2TNA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		4 / 5 LEU A 101
ILE A  99
SER A  96
GLY A  95
 None
 0.91A 2otfA-3qr1A:
undetectable		 2otfA-3qr1A:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		3 / 3 LEU A 456
PRO A 457
LEU A 329
 None
 0.39A 2po7B-3qr1A:
3.4		 2po7B-3qr1A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1104_0
(FERROCHELATASE)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		3 / 3 LEU A 456
PRO A 457
LEU A 329
 None
 0.49A 2qd5B-3qr1A:
3.2		 2qd5B-3qr1A:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_2
(PROGESTERONE
RECEPTOR)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		4 / 7 LEU A 313
ASN A 312
GLU A 310
TYR A 616
 None
 1.21A 2w8yA-3qr1A:
undetectable		 2w8yA-3qr1A:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_A_SAMA300_0
(PUTATIVE RRNA
METHYLASE)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		5 / 12 GLY A 744
ASP A 256
ILE A 741
GLY A 740
HIS A 260
 None
 1.13A 3eeyA-3qr1A:
undetectable		 3eeyA-3qr1A:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_B_SAMB300_0
(PUTATIVE RRNA
METHYLASE)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		5 / 12 GLY A 744
ASP A 256
ILE A 741
GLY A 740
HIS A 260
 None
 1.12A 3eeyB-3qr1A:
2.2		 3eeyB-3qr1A:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_0
(PUTATIVE RRNA
METHYLASE)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		5 / 12 GLY A 744
ASP A 256
ILE A 741
GLY A 740
HIS A 260
 None
 1.14A 3eeyC-3qr1A:
undetectable		 3eeyC-3qr1A:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_0
(PUTATIVE RRNA
METHYLASE)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		5 / 12 GLY A 744
ASP A 256
ILE A 741
GLY A 740
HIS A 260
 None
 1.15A 3eeyD-3qr1A:
undetectable		 3eeyD-3qr1A:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_0
(PUTATIVE RRNA
METHYLASE)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		5 / 12 GLY A 744
ASP A 256
ILE A 741
GLY A 740
HIS A 260
 None
 1.14A 3eeyE-3qr1A:
undetectable		 3eeyE-3qr1A:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_F_SAMF300_0
(PUTATIVE RRNA
METHYLASE)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		5 / 12 GLY A 744
ASP A 256
ILE A 741
GLY A 740
HIS A 260
 None
 1.13A 3eeyF-3qr1A:
2.8		 3eeyF-3qr1A:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_H_SAMH300_0
(PUTATIVE RRNA
METHYLASE)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		5 / 12 GLY A 744
ASP A 256
ILE A 741
GLY A 740
HIS A 260
 None
 1.13A 3eeyH-3qr1A:
undetectable		 3eeyH-3qr1A:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_I_SAMI300_0
(PUTATIVE RRNA
METHYLASE)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		5 / 12 GLY A 744
ASP A 256
ILE A 741
GLY A 740
HIS A 260
 None
 1.14A 3eeyI-3qr1A:
undetectable		 3eeyI-3qr1A:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_J_SAMJ300_0
(PUTATIVE RRNA
METHYLASE)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		5 / 12 GLY A 744
ASP A 256
ILE A 741
GLY A 740
HIS A 260
 None
 1.13A 3eeyJ-3qr1A:
undetectable		 3eeyJ-3qr1A:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		3 / 3 LEU A 456
PRO A 457
LEU A 329
 None
 0.44A 3hcrA-3qr1A:
3.6		 3hcrA-3qr1A:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_0
(YAEB-LIKE PROTEIN
RPA0152)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		3 / 3 LYS A 326
ARG A 463
LYS A  11
 None
 1.15A 3okxA-3qr1A:
undetectable		 3okxA-3qr1A:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_1
(YAEB-LIKE PROTEIN
RPA0152)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		5 / 12 LEU A  29
GLY A  91
THR A  92
CYH A 105
LEU A 122
 None
 1.24A 3okxB-3qr1A:
undetectable		 3okxB-3qr1A:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UGR_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		4 / 7 TYR A 283
ASN A 150
TYR A 745
PRO A 749
 None
 1.17A 3ugrA-3qr1A:
undetectable		 3ugrA-3qr1A:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		3 / 3 LEU A 456
PRO A 457
LEU A 329
 None
 0.48A 3w1wB-3qr1A:
2.7		 3w1wB-3qr1A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_B_P1BB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		5 / 12 TRP A 133
LEU A  43
LEU A  65
ILE A  73
ILE A 120
 None
 1.38A 4a79B-3qr1A:
undetectable		 4a79B-3qr1A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		4 / 8 SER A 543
ARG A 570
GLU A 546
ILE A 571
 None
 0.95A 4d33A-3qr1A:
undetectable		 4d33A-3qr1A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		4 / 7 SER A 543
ARG A 570
GLU A 546
ILE A 571
 None
 1.02A 4d33B-3qr1A:
undetectable		 4d33B-3qr1A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		4 / 8 SER A 543
ARG A 570
GLU A 546
ILE A 571
 None
 1.06A 4d39A-3qr1A:
undetectable		 4d39A-3qr1A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		4 / 7 SER A 543
ARG A 570
GLU A 546
ILE A 571
 None
 0.98A 4d39B-3qr1A:
undetectable		 4d39B-3qr1A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F3T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		4 / 6 LEU A 303
TYR A 304
LEU A 223
TYR A 222
 None
 0.77A 4f3tA-3qr1A:
2.6		 4f3tA-3qr1A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_A_ACTA502_0
(RNA-DEPENDENT RNA
POLYMERASE)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		4 / 5 LYS A 157
LEU A 158
GLU A 154
LEU A 760
 None
 1.30A 4k4yA-3qr1A:
undetectable		 4k4yA-3qr1A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_E_ACTE503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		4 / 4 LYS A 157
LEU A 158
GLU A 154
LEU A 760
 None
 1.31A 4k4yE-3qr1A:
undetectable		 4k4yE-3qr1A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_I_ACTI503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		4 / 5 LYS A 157
LEU A 158
GLU A 154
LEU A 760
 None
 1.35A 4k4yI-3qr1A:
undetectable		 4k4yI-3qr1A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_A_20JA602_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		4 / 7 VAL A 719
ILE A 721
ILE A 748
ALA A 765
 None
 0.82A 4lv9A-3qr1A:
3.4		 4lv9A-3qr1A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA304_1
(TYROSINASE)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		4 / 5 ASN A 339
HIS A 338
GLU A 417
THR A 503
 CA  A1000 (-2.5A)
CA  A1000 ( 4.8A)
CA  A1000 (-3.1A)
None
 1.47A 4p6sA-3qr1A:
undetectable		 4p6sA-3qr1A:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RJD_B_TFPB204_1
(CALMODULIN)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		4 / 8 LEU A 369
GLU A 368
GLU A 507
ALA A 508
 None
CA  A1000 (-3.1A)
None
None
 0.80A 4rjdA-3qr1A:
7.9
4rjdB-3qr1A:
7.4		 4rjdA-3qr1A:
6.17
4rjdB-3qr1A:
6.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_1
(BETA-LACTOGLOBULIN)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		3 / 3 LYS A 469
ILE A 413
ILE A 334
 None
 0.66A 4y0qA-3qr1A:
undetectable		 4y0qA-3qr1A:
11.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YOA_A_017A100_1
(HIV-1 PROTEASE)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		4 / 6 ASP A 645
PRO A 679
THR A 680
VAL A 712
 None
 1.07A 4yoaA-3qr1A:
undetectable		 4yoaA-3qr1A:
8.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		4 / 7 LEU A 303
TYR A 304
LEU A 223
TYR A 222
 None
 0.81A 4z4fA-3qr1A:
undetectable		 4z4fA-3qr1A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J6H_A_NCAA402_0
(H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, Q10 ALPHA
CHAIN)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		3 / 3 PRO A 749
ARG A 751
GLU A 154
 None
 0.93A 5j6hA-3qr1A:
undetectable		 5j6hA-3qr1A:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		3 / 3 LYS A 665
ASP A 664
ARG A 188
 None
 1.02A 5jwaA-3qr1A:
undetectable
5jwaH-3qr1A:
undetectable		 5jwaA-3qr1A:
21.03
5jwaH-3qr1A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KI6_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		4 / 5 LEU A 303
TYR A 304
LEU A 223
TYR A 222
 None
 0.83A 5ki6A-3qr1A:
undetectable		 5ki6A-3qr1A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_A_PFLA412_1
(PROTON-GATED ION
CHANNEL)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		5 / 10 TYR A 701
ILE A 721
ILE A 722
TYR A 670
THR A 689
 None
 1.38A 5mzrA-3qr1A:
undetectable		 5mzrA-3qr1A:
7.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		4 / 7 LEU A 303
TYR A 304
LEU A 223
TYR A 222
 None
 0.84A 5t7bA-3qr1A:
2.4		 5t7bA-3qr1A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA405_0
(THIOREDOXIN
REDUCTASE)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		3 / 3 GLY A 437
LEU A 440
HIS A 433
 None
 0.66A 5u63A-3qr1A:
undetectable		 5u63A-3qr1A:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_B_ACTB405_0
(THIOREDOXIN
REDUCTASE)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		3 / 3 GLY A 437
LEU A 440
HIS A 433
 None
 0.67A 5u63B-3qr1A:
undetectable		 5u63B-3qr1A:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_2
(CYTOCHROME P450 3A5)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		4 / 5 ARG A 756
PHE A 614
LEU A 611
LEU A 319
 None
 1.36A 5veuH-3qr1A:
undetectable		 5veuH-3qr1A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		4 / 6 VAL A 605
ASN A 724
ILE A 722
GLU A 672
 None
 1.17A 6h7uA-3qr1A:
undetectable		 6h7uA-3qr1A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)
(Doryteuthis
pealeii) 		4 / 8 VAL A 605
ASN A 724
ILE A 722
GLU A 672
 None
 0.96A 6hzpA-3qr1A:
undetectable		 6hzpA-3qr1A:
20.53