SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qr3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDT_A_VIAA1000_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3qr3 ENDOGLUCANASE EG-II
(Trichoderma
reesei) 		5 / 12 TYR A  28
ALA A  10
LEU A  88
MET A  47
GLN A  46
 None
 1.19A 1udtA-3qr3A:
undetectable		 1udtA-3qr3A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_A_NBVA1503_1
(GLUCOSYLCERAMIDASE)		 3qr3 ENDOGLUCANASE EG-II
(Trichoderma
reesei) 		6 / 12 ASN A 147
GLU A 148
HIS A 218
TYR A 220
GLU A 259
TRP A 292
 None
SO4  A 346 ( 4.1A)
None
SO4  A 346 (-4.6A)
SO4  A 346 (-3.6A)
SO4  A 346 (-3.3A)
 0.74A 2v3dA-3qr3A:
5.4		 2v3dA-3qr3A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_B_NBVB1504_1
(GLUCOSYLCERAMIDASE)		 3qr3 ENDOGLUCANASE EG-II
(Trichoderma
reesei) 		5 / 11 ASN A 147
GLU A 148
TYR A 220
GLU A 259
TRP A 292
 None
SO4  A 346 ( 4.1A)
SO4  A 346 (-4.6A)
SO4  A 346 (-3.6A)
SO4  A 346 (-3.3A)
 0.82A 2v3dB-3qr3A:
18.5		 2v3dB-3qr3A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB4_0
(FERROCHELATASE)		 3qr3 ENDOGLUCANASE EG-II
(Trichoderma
reesei) 		4 / 6 MET A  47
ARG A  60
PRO A 307
GLY A 293
 None
 1.38A 3aqiB-3qr3A:
undetectable		 3aqiB-3qr3A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3qr3 ENDOGLUCANASE EG-II
(Trichoderma
reesei) 		5 / 12 GLY A  91
VAL A 141
GLY A  45
PHE A  50
ALA A 294
 None
 0.87A 3sudD-3qr3A:
undetectable		 3sudD-3qr3A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3qr3 ENDOGLUCANASE EG-II
(Trichoderma
reesei) 		5 / 12 GLY A  91
VAL A 141
GLY A  45
PHE A  50
ALA A 294
 None
 0.86A 3sueC-3qr3A:
undetectable		 3sueC-3qr3A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3qr3 ENDOGLUCANASE EG-II
(Trichoderma
reesei) 		5 / 12 GLY A  91
VAL A 141
GLY A  45
PHE A  50
ALA A 294
 None
 0.89A 3sufD-3qr3A:
undetectable		 3sufD-3qr3A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUG_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3qr3 ENDOGLUCANASE EG-II
(Trichoderma
reesei) 		5 / 12 GLY A  91
VAL A 141
GLY A  45
PHE A  50
ALA A 294
 None
 0.91A 3sugA-3qr3A:
undetectable		 3sugA-3qr3A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_A_SASA806_1
(SEPIAPTERIN
REDUCTASE)		 3qr3 ENDOGLUCANASE EG-II
(Trichoderma
reesei) 		5 / 12 LEU A  31
PHE A  12
TYR A  28
GLN A  46
ASP A 102
 None
 1.50A 4j7xA-3qr3A:
undetectable		 4j7xA-3qr3A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_F_SASF805_1
(SEPIAPTERIN
REDUCTASE)		 3qr3 ENDOGLUCANASE EG-II
(Trichoderma
reesei) 		5 / 12 LEU A  31
PHE A  12
TYR A  28
GLN A  46
ASP A 102
 None
 1.49A 4j7xF-3qr3A:
undetectable		 4j7xF-3qr3A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_J_SASJ804_1
(SEPIAPTERIN
REDUCTASE)		 3qr3 ENDOGLUCANASE EG-II
(Trichoderma
reesei) 		5 / 12 LEU A  31
PHE A  12
TYR A  28
GLN A  46
ASP A 102
 None
 1.48A 4j7xJ-3qr3A:
undetectable		 4j7xJ-3qr3A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOU_A_C04A207_1
(UNCHARACTERIZED
PROTEIN)		 3qr3 ENDOGLUCANASE EG-II
(Trichoderma
reesei) 		3 / 3 GLY A 295
GLU A 305
THR A 304
 None
 0.59A 4kouA-3qr3A:
0.4		 4kouA-3qr3A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCU_B_SAMB603_0
(CYSTATHIONINE
BETA-SYNTHASE)		 3qr3 ENDOGLUCANASE EG-II
(Trichoderma
reesei) 		5 / 9 ASP A 102
LEU A 213
ASP A 216
VAL A 161
ILE A 103
 None
 1.44A 4pcuA-3qr3A:
1.5
4pcuB-3qr3A:
undetectable		 4pcuA-3qr3A:
19.89
4pcuB-3qr3A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_A_ML1A302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3qr3 ENDOGLUCANASE EG-II
(Trichoderma
reesei) 		4 / 8 ILE A 214
PHE A 241
GLY A 288
ILE A  58
 None
 0.97A 4qogA-3qr3A:
undetectable
4qogB-3qr3A:
undetectable		 4qogA-3qr3A:
20.06
4qogB-3qr3A:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_C_P06C801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3qr3 ENDOGLUCANASE EG-II
(Trichoderma
reesei) 		4 / 7 VAL A 290
PHE A  59
ILE A   9
ASN A 105
 None
 0.93A 5hieC-3qr3A:
undetectable		 5hieC-3qr3A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_C_SALC201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 3qr3 ENDOGLUCANASE EG-II
(Trichoderma
reesei) 		4 / 7 VAL A 161
VAL A 152
PRO A 149
GLY A 182
 None
 0.91A 5x80C-3qr3A:
undetectable
5x80D-3qr3A:
undetectable		 5x80C-3qr3A:
17.47
5x80D-3qr3A:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA606_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 3qr3 ENDOGLUCANASE EG-II
(Trichoderma
reesei) 		4 / 5 GLU A 148
ASP A 102
HIS A 104
THR A 258
 SO4  A 346 ( 4.1A)
None
None
None
 1.30A 6b58A-3qr3A:
undetectable		 6b58A-3qr3A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_0
(NS3 PROTEASE)		 3qr3 ENDOGLUCANASE EG-II
(Trichoderma
reesei) 		5 / 12 GLY A  91
VAL A 141
GLY A  45
PHE A  50
ALA A 294
 None
 0.74A 6c2mD-3qr3A:
undetectable		 6c2mD-3qr3A:
12.84