SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qr5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_A_TRPA602_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3qr5 CARDIAC CA2+ RELEASE
CHANNEL
(Mus
musculus) 		4 / 8 ILE A 119
LEU A 181
ILE A 182
HIS A 163
 None
 0.81A 2azxA-3qr5A:
undetectable		 2azxA-3qr5A:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3qr5 CARDIAC CA2+ RELEASE
CHANNEL
(Mus
musculus) 		4 / 5 GLN A  33
THR A  27
THR A 210
HIS A 193
 None
 1.13A 2zj0A-3qr5A:
undetectable		 2zj0A-3qr5A:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_B_2FAB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3qr5 CARDIAC CA2+ RELEASE
CHANNEL
(Mus
musculus) 		4 / 5 GLN A  33
THR A  27
THR A 210
HIS A 193
 None
 1.19A 2zj0B-3qr5A:
undetectable		 2zj0B-3qr5A:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_C_2FAC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3qr5 CARDIAC CA2+ RELEASE
CHANNEL
(Mus
musculus) 		4 / 5 GLN A  33
THR A  27
THR A 210
HIS A 193
 None
 1.11A 2zj0C-3qr5A:
undetectable		 2zj0C-3qr5A:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_A_ADNA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3qr5 CARDIAC CA2+ RELEASE
CHANNEL
(Mus
musculus) 		4 / 5 GLN A  33
THR A  27
THR A 210
HIS A 193
 None
 1.10A 3ce6A-3qr5A:
undetectable		 3ce6A-3qr5A:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_B_ADNB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3qr5 CARDIAC CA2+ RELEASE
CHANNEL
(Mus
musculus) 		4 / 5 GLN A  33
THR A  27
THR A 210
HIS A 193
 None
 1.09A 3ce6B-3qr5A:
undetectable		 3ce6B-3qr5A:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3qr5 CARDIAC CA2+ RELEASE
CHANNEL
(Mus
musculus) 		4 / 5 GLN A  33
THR A  27
THR A 210
HIS A 193
 None
 1.08A 3ce6C-3qr5A:
undetectable		 3ce6C-3qr5A:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_A_ADNA438_2
(ADENOSYLHOMOCYSTEINA
SE)		 3qr5 CARDIAC CA2+ RELEASE
CHANNEL
(Mus
musculus) 		4 / 4 GLN A  33
THR A  27
THR A 210
HIS A 193
 None
 1.12A 3g1uA-3qr5A:
undetectable		 3g1uA-3qr5A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_C_ADNC438_2
(ADENOSYLHOMOCYSTEINA
SE)		 3qr5 CARDIAC CA2+ RELEASE
CHANNEL
(Mus
musculus) 		4 / 5 GLN A  33
THR A  27
THR A 210
HIS A 193
 None
 1.15A 3g1uC-3qr5A:
undetectable		 3g1uC-3qr5A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_A_RABA602_2
(ADENOSYLHOMOCYSTEINA
SE)		 3qr5 CARDIAC CA2+ RELEASE
CHANNEL
(Mus
musculus) 		4 / 5 GLN A  33
THR A  27
THR A 210
HIS A 193
 None
 1.07A 3glqA-3qr5A:
undetectable		 3glqA-3qr5A:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_B_RABB602_2
(ADENOSYLHOMOCYSTEINA
SE)		 3qr5 CARDIAC CA2+ RELEASE
CHANNEL
(Mus
musculus) 		4 / 5 GLN A  33
THR A  27
THR A 210
HIS A 193
 None
 1.08A 3glqB-3qr5A:
undetectable		 3glqB-3qr5A:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_A_ADNA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3qr5 CARDIAC CA2+ RELEASE
CHANNEL
(Mus
musculus) 		4 / 5 GLN A  33
THR A  27
THR A 210
HIS A 193
 None
 1.09A 3n58A-3qr5A:
undetectable		 3n58A-3qr5A:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_G_IPHG101_0
(INSULIN)		 3qr5 CARDIAC CA2+ RELEASE
CHANNEL
(Mus
musculus) 		5 / 11 LEU A  49
CYH A  47
LEU A  37
HIS A 193
LEU A 192
 None
 1.14A 4p65B-3qr5A:
undetectable
4p65D-3qr5A:
undetectable
4p65G-3qr5A:
undetectable
4p65H-3qr5A:
undetectable		 4p65B-3qr5A:
13.61
4p65D-3qr5A:
13.61
4p65G-3qr5A:
8.81
4p65H-3qr5A:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPU_C_IPHC101_0
(INSULIN, CHAIN A
INSULIN, CHAIN B)		 3qr5 CARDIAC CA2+ RELEASE
CHANNEL
(Mus
musculus) 		4 / 6 CYH A  47
LEU A  37
HIS A 193
LEU A 192
 None
 0.76A 5hpuC-3qr5A:
undetectable
5hpuD-3qr5A:
undetectable		 5hpuC-3qr5A:
8.81
5hpuD-3qr5A:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WWS_A_SAMA501_0
(PUTATIVE
METHYLTRANSFERASE
NSUN6)		 3qr5 CARDIAC CA2+ RELEASE
CHANNEL
(Mus
musculus) 		5 / 12 ALA A 206
ASP A 204
GLY A 148
LEU A  37
LEU A 130
 None
 1.17A 5wwsA-3qr5A:
undetectable		 5wwsA-3qr5A:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3qr5 CARDIAC CA2+ RELEASE
CHANNEL
(Mus
musculus) 		4 / 5 GLN A  33
THR A  27
THR A 210
HIS A 193
 None
 1.13A 6aphA-3qr5A:
undetectable		 6aphA-3qr5A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_A_ADNA505_2
(-)		 3qr5 CARDIAC CA2+ RELEASE
CHANNEL
(Mus
musculus) 		4 / 4 GLN A  33
THR A  27
THR A 210
HIS A 193
 None
 1.11A 6f3nA-3qr5A:
undetectable		 6f3nA-3qr5A:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_C_ADNC505_2
(-)		 3qr5 CARDIAC CA2+ RELEASE
CHANNEL
(Mus
musculus) 		4 / 4 GLN A  33
THR A  27
THR A 210
HIS A 193
 None
 1.12A 6f3nC-3qr5A:
undetectable		 6f3nC-3qr5A:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_D_ADND506_2
(-)		 3qr5 CARDIAC CA2+ RELEASE
CHANNEL
(Mus
musculus) 		4 / 4 GLN A  33
THR A  27
THR A 210
HIS A 193
 None
 1.11A 6f3nD-3qr5A:
undetectable		 6f3nD-3qr5A:
18.38