SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qs2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RQW_I_ACHI323_0 (ELIC PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI)	3qs2	FIMBRILLIN MATB HOMOLOG (Escherichia coli)	4 / 8	ILE A 138 TYR A 151 LEU A 154 PHE A 42	None	0.97A	3rqwI-3qs2A: undetectable 3rqwJ-3qs2A: undetectable	3rqwI-3qs2A: 20.12 3rqwJ-3qs2A: 20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MM8_A_RFXA603_1 (TRANSPORTER)	3qs2	FIMBRILLIN MATB HOMOLOG (Escherichia coli)	5 / 12	VAL A 148 ALA A 147 GLY A 144 ASP A 150 THR A 153	IOD A 205 ( 4.0A) None None None None	1.22A	4mm8A-3qs2A: undetectable	4mm8A-3qs2A: 16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5D75_A_FK5A301_1 (PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP3)	3qs2	FIMBRILLIN MATB HOMOLOG (Escherichia coli)	5 / 11	TYR A 89 ASP A 131 VAL A 109 ILE A 103 ALA A 129	None	1.05A	5d75A-3qs2A: undetectable	5d75A-3qs2A: 16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VLM_H_CVIH301_1 (REGULATORY PROTEIN TETR)	3qs2	FIMBRILLIN MATB HOMOLOG (Escherichia coli)	4 / 8	GLN A 34 GLY A 41 ILE A 137 TRP A 159	None	1.01A	5vlmH-3qs2A: undetectable	5vlmH-3qs2A: 18.14

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3RQW_I_ACHI323_0","ELIC PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI","3qs2","FIMBRILLIN MATB HOMOLOG","Escherichia coli",4,"ILE A 138;TYR A 151;LEU A 154;PHE A  42","None","0.97A","3rqwI-3qs2A:undetectable;3rqwJ-3qs2A:undetectable","3rqwI-3qs2A:20.12;3rqwJ-3qs2A:20.12"],["4MM8_A_RFXA603_1","TRANSPORTER","3qs2","FIMBRILLIN MATB HOMOLOG","Escherichia coli",5,"VAL A 148;ALA A 147;GLY A 144;ASP A 150;THR A 153","IOD A 205 ( 4.0A);None;None;None;None","1.22A","4mm8A-3qs2A:undetectable","4mm8A-3qs2A:16.31"],["5D75_A_FK5A301_1","PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP3","3qs2","FIMBRILLIN MATB HOMOLOG","Escherichia coli",5,"TYR A  89;ASP A 131;VAL A 109;ILE A 103;ALA A 129","None","1.05A","5d75A-3qs2A:undetectable","5d75A-3qs2A:16.92"],["5VLM_H_CVIH301_1","REGULATORY PROTEIN TETR","3qs2","FIMBRILLIN MATB HOMOLOG","Escherichia coli",4,"GLN A  34;GLY A  41;ILE A 137;TRP A 159","None","1.01A","5vlmH-3qs2A:undetectable","5vlmH-3qs2A:18.14"]]